Date published: 2025-9-7

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NMU-23 抗体 (A-5): sc-398600

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说明书
  • NMU-23 抗体 A-5 是小鼠单克隆 IgG1 (kappa轻链),NMU-23抗体,规格为200 µg/ml
  • 免疫原氨基酸序列32-107位于mouse物种的NMU-23的内部区域内
  • NMU-23 抗体 (A-5) 推荐用于 WB, IP, IF 和 ELISA,检测mouse 和rat 来源的 NMU-23
  • 抗NMU-23抗体(A-5)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取NMU-23 (A-5): sc-398600免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是NMU-23 Antibody (A-5) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与NMU-23 Antibody (A-5) 打包提供(请参阅下面的订购信息)。

    快捷链接

    関連項目

    NMU-23抗体(A-5)是一种IgG1κ小鼠单克隆NMU-23抗体(也称为NMU-23抗体),可通过WB、IP、IF和ELISA检测小鼠和大鼠来源的NMU-23蛋白。NMU-23抗体(A-5)既有非偶联抗NMU-23抗体形式,也有多种偶联形式的抗NMU-23抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。神经调节素U(NMU)是一种神经肽,对平滑肌具有强收缩活性,最初在猪脊髓中发现。NMU广泛分布于胃肠道和神经系统,在十二指肠和空肠中表达水平最高,在脊髓、下丘脑和胃中表达水平较低。NMU的受体为FM-3/NMU1R,在外周组织中显著表达,以及FM-4/NMU2R,在大脑的特定区域表达。174个氨基酸的大鼠NMU前体编码一个以上的生物活性肽,该生物活性肽在NMU前体的C末端附近包含23个残基的NMU肽(NMU-23)。NMU具有一个疏水信号肽和多个成对的双碱性氨基酸,这些氨基酸作为酶解信号,释放NMU和其他肽。NMU-23和其他NMU肽具有相似的功能,但在长度和活性上有所不同,这些都具有组织和物种特异性。在大鼠中,NMU-23刺激胃环行肌收缩,并参与摄食的中枢控制。NMU的外周活动包括刺激平滑肌、升高血压、改变肠道离子转运、控制局部血流和调节肾上腺皮质功能。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    NMU-23 抗体 (A-5) 参考文献:

    1. 神经生长素 U 受体的鉴定及其在摄食中的作用  |  Howard, AD., et al. 2000. Nature. 406: 70-4. PMID: 10894543
    2. 编码大鼠神经介素 U 前体的互补 DNA 的特征。  |  Lo, G., et al. 1992. Mol Endocrinol. 6: 1538-44. PMID: 1448109
    3. 体外神经生长因子 U 对大鼠胃的运动效应  |  Benito-Orfila, MA., et al. 1991. Eur J Pharmacol. 193: 329-33. PMID: 2055247
    4. 神经生长因子 U 在清醒大鼠体内的区域血液动力学效应。  |  Gardiner, SM., et al. 1990. Am J Physiol. 258: R32-8. PMID: 2301645
    5. 7B2, 神经生长因子 B 和神经生长因子 U 在大鼠, 小鼠和人类垂体特定细胞类型, 大鼠下丘脑以及 30 种人类垂体和垂体外肿瘤中的定位。  |  Steel, JH., et al. 1988. Endocrinology. 122: 270-82. PMID: 3335208
    6. 神经生长因子 U--大鼠体内分布研究  |  Domin, J., et al. 1987. Peptides. 8: 779-84. PMID: 3432125
    7. 克隆编码人类神经生长素 U(NmU)前体的 cDNA 并确定其特征:NmU 在人类胃肠道中的表达。  |  Austin, C., et al. 1995. J Mol Endocrinol. 14: 157-69. PMID: 7619205
    8. 大鼠胃肠道中神经生长素 U 的分布和表达发育模式  |  Austin, C., et al. 1994. J Mol Endocrinol. 12: 257-63. PMID: 7916966

    订购信息

    产品名称产品编号规格价格数量收藏夹

    NMU-23 抗体 (A-5)

    sc-398600
    200 µg/ml
    RMB2377.00

    NMU-23 (A-5): m-IgG Fc BP-HRP 套装

    sc-530865
    200 µg Ab; 10 µg BP
    RMB2662.00

    NMU-23 (A-5): m-IgGκ BP-HRP 套装

    sc-524414
    200 µg Ab, 40 µg BP
    RMB2662.00

    NMU-23 (A-5): m-IgG1 BP-HRP 套装

    sc-544288
    200 µg Ab; 20 µg BP
    RMB2662.00

    NMU-23 抗体 (A-5) AC

    sc-398600 AC
    500 µg/ml, 25% agarose
    RMB3129.00

    NMU-23 抗体 (A-5) HRP

    sc-398600 HRP
    200 µg/ml
    RMB2377.00

    NMU-23 抗体 (A-5) FITC

    sc-398600 FITC
    200 µg/ml
    RMB2482.00

    NMU-23 抗体 (A-5) PE

    sc-398600 PE
    200 µg/ml
    RMB2580.00

    NMU-23 抗体 (A-5) Alexa Fluor® 488

    sc-398600 AF488
    200 µg/ml
    RMB2685.00

    NMU-23 抗体 (A-5) Alexa Fluor® 546

    sc-398600 AF546
    200 µg/ml
    RMB2685.00

    NMU-23 抗体 (A-5) Alexa Fluor® 594

    sc-398600 AF594
    200 µg/ml
    RMB2685.00

    NMU-23 抗体 (A-5) Alexa Fluor® 647

    sc-398600 AF647
    200 µg/ml
    RMB2685.00

    NMU-23 抗体 (A-5) Alexa Fluor® 680

    sc-398600 AF680
    200 µg/ml
    RMB2685.00

    NMU-23 抗体 (A-5) Alexa Fluor® 790

    sc-398600 AF790
    200 µg/ml
    RMB2685.00

    Can this antibody stain paraffin sections of intestinal tissue

    Asked by: Izzie
    Thank you for your question. We have not yet tested NMU-23 Antibody (A-5): sc-398600 on IHC. As a result, IHC is not currently a recommended application for this antibody. 感谢您的提问。目前sc-398600还没有做IHC实验的验证,因此,目前不推荐IHC这个实验应用。
    Answered by: Yanru Tao
    Date published: 2025-08-08

    Does this antibody work for IFC staining in mouse pancreas ? any references ? Thanks !

    Asked by: TT DONG
    Thank you for your question. Anti-NMU-23 Antibody (A-5) is recommended for detection of NMU-23 of mouse and rat origin by WB, IP, IF and ELISA. It is not recommended for histological stainings.
    Answered by: Tech Support Europe
    Date published: 2022-08-03

    Hello, may I ask if this antibody works in human cells? Thanks!

    Asked by: jojo1234
    Thank you for your question. We have only validated this antibody for mouse and rat . Sequence analysis shows very low to no homology between the epitope sequence of the antibody and the target in human. If you have additional questions, please contact Technical Support at 1800-457-3801 option 2, by emailing [email protected] or by live chat on our website at www.scbt.com so we may further assist you.
    Answered by: Blake J
    Date published: 2021-07-07

    Is these antibody mouse-anti-mouse or Rabbit-anti-mouse ? One Nature paper "The neuropeptide neuromedin U stimulates innate lymphoid cells and " The following antibodies were used: rabbit anti-NMU (Santa Cruz), ...Is it Rabbit anti NMU????

    Asked by: bxh1111
    Thank you for your question. Anti-NMU-23 Antibody (A-5) is a mouse monoclonal IgG1 that NMU-23 of mouse and rat origin by WB, IP, IF and ELISA. It is not (and never has been) a rabbit antibody.
    Answered by: Tech Support Europe
    Date published: 2025-06-10

    what is the secondary antibody for the Nmu23? (Host source for the antibody)

    Asked by: lhz1206
    Thank you for your question. NMU-23 Antibody (A-5): sc-398600 is a mouse monoclonal IgG1 kappa antibody. It can be detected with any of our kappa-specific secondary binding proteins, which can be found under this link: https://www.scbt.com/browse/support-products-Mouse-IgG-Binding-Proteins/_/N-130b1ry
    Answered by: Technical Support Europe
    Date published: 2021-04-23

    I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with NMU-23 (A-5): sc-398600?

    Asked by: jerojero
    We recommend using one of our our exclusive Mouse IgG Binding Proteins conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
    Answered by: Technical Support
    Date published: 2017-02-27
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    Rated 5 out of 5 by from Produced positive Western blot data of NMUProduced positive Western blot data of NMU-23 expression in rat small intestine and mouse small intestine tissue extracts. -SCBT QC
    Date published: 2013-10-09
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    NMU-23 抗体 (A-5) is rated 5.0 out of 5 by 1.
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