NKp44 抗体 (3.43): sc-53598
- NKp44抗体(3.43)是小鼠单克隆IgG1 (kappa轻链)，规格为200 µg/ml
- 免疫human物种的NKp44
- 推荐用于 human 来源的NKp44 FCM检测
- 还可偶联藻红蛋白 以及 FITC 用于IF, IHC(P) 和 FCM
- m-IgG Fc BP-HRP、 1 BP-HRP">m-IgG1 BP-HRP和m-IgGκ BP-HRP是NKp44 Antibody (3.43). 的首选辅助检测试剂。这些试剂现与NKp44 Antibody (3.43) 打包提供（请参阅下面的订购信息）。
Natural killer (NK) cells direct cytotoxicity against tumor or virally infected cells. NK cell-mediated cytotoxicity is stimulated by several activating receptors associated with the signaling adapter DNAX activation 12/killer cell-activating receptor-associated protein (DAP12). NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis. NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level. A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load. This implicates NKp44 as a therapeutic agent that may aid in the progress towards a vaccine for HIV-1 infection.
订购信息
| 产品名称 | 产品编号 | 规格 | 价格 | 数量 | 收藏夹 | |
NKp44 抗体 (3.43) | sc-53598 | 200 µg/ml | RMB2377.00 | |||
NKp44 (3.43): m-IgG Fc BP-HRP 套装 | sc-536993 | 200 µg Ab; 10 µg BP | RMB2662.00 | |||
NKp44 (3.43): m-IgGκ BP-HRP 套装 | sc-534173 | 200 µg Ab; 40 µg BP | RMB2662.00 | |||
NKp44 (3.43): m-IgG1 BP-HRP 套装 | sc-544945 | 200 µg Ab; 20 µg BP | RMB2662.00 | |||
NKp44 抗体 (3.43) FITC | sc-53598 FITC | 200 µg/ml | RMB2482.00 | |||
NKp44 抗体 (3.43) PE | sc-53598 PE | 200 µg/ml | RMB2580.00 |