Date published: 2025-9-8
访问圣克鲁斯动物健康

021-6093-6350

SCBT Portrait Logo
Seach Input
联系我们
登陆账户
快速订购
购物车 (0)
NF-H Antibody (2D2) - Western Blotting - Image 372863
NF-H 抗体 (2D2): sc-20014. 人大脑皮层组织提取物中 NF-H 表达的 Western 印迹分析.
NF-H 抗体 (2D2): sc-20014. 人大脑皮层组织提取物中 NF-H 表达的 Western 印迹分析.

NF-H 抗体 (2D2): sc-20014

4.3(4)
寫評論提問

说明书
  • NF-H抗体(2D2)是小鼠单克隆IgM κ, 在2篇文献中引用，规格为200 µg/ml
  • 针对从human脑中纯化的神经丝
  • 推荐用于 mouse, rat 和 human 来源的NF-H WB, IP 和 IF检测
  • 目前，我们还没有完成NF-H 抗体 (2D2)的首选二抗检测试剂的鉴定。这项工作正在进行中。

快捷链接

相关产品
描述
基因信息
说明书与实验方案
研究信息

関連項目

此外 NF 抗体 包括 NF-H, NF-L和NF-M

神经丝蛋白H（NF-H）是神经丝重多肽的简称，属于中间丝蛋白家族的一员，是神经元细胞骨架的主要组成部分。神经丝是动态的结构；它们包含大量蛋白激酶的磷酸化位点，包括蛋白激酶A、蛋白激酶C、细胞周期蛋白依赖性激酶5、细胞外信号调节激酶、糖原合成酶激酶-3以及应激激活的蛋白激酶γ。除了控制轴突口径的作用外，神经丝还可能影响其他细胞骨架元素，如微管和肌动蛋白丝。在神经退行性疾病中，经常可以观察到神经丝磷酸化或代谢的变化，这些疾病包括肌萎缩侧索硬化症（ALS）、帕金森病和阿尔茨海默病。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

NF-H 抗体 (2D2) 参考文献:

  1. 唐氏综合征和阿尔茨海默氏病患者的脑神经丝蛋白NF-L、NF-M和NF-H。  |  Bajo, M., et al. 2001. Amino Acids. 21: 293-301. PMID: 11764410
  2. 高磷酸化神经丝NF-H是轴突损伤的血清生物标志物。  |  Shaw, G., et al. 2005. Biochem Biophys Res Commun. 336: 1268-77. PMID: 16176808
  3. 高磷酸化神经丝NF-H可预测儿童脑损伤后的死亡率。  |  Zurek, J., et al. 2011. Brain Inj. 25: 221-6. PMID: 21219092
  4. NF-H 和 NF-M 亚基的 C 端结构域通过阻止静止神经丝网络的周转来维持轴突神经丝的含量。  |  Rao, MV., et al. 2012. PLoS One. 7: e44320. PMID: 23028520
  5. 在急性压迫性脊髓病症状恶化患者的脑脊液中，神经丝亚基NF-H的磷酸化水平升高。  |  Takahashi, H., et al. 2014. J Clin Neurosci. 21: 2175-8. PMID: 25065845
  6. 发育中大鼠内耳中神经丝三聚体蛋白亚型NF-L、NF-M和NF-H的表达。  |  Nishizaki, K. and Anniko, M. 1995. ORL J Otorhinolaryngol Relat Spec. 57: 177-81. PMID: 7478449
  7. 增加神经丝亚基NF-M的表达会减少轴突NF-H，抑制径向生长，并导致运动神经元中的神经丝积聚。  |  Wong, PC., et al. 1995. J Cell Biol. 130: 1413-22. PMID: 7559762
  8. 神经丝蛋白（NF-H）中的神经元细胞周期蛋白依赖性激酶-5磷酸化位点被蛋白磷酸酶2A去磷酸化。  |  Veeranna,., et al. 1995. J Neurochem. 64: 2681-90. PMID: 7760048
  9. 神经丝亚基NF-H通过选择性减慢神经丝运输来调节轴突直径。  |  Marszalek, JR., et al. 1996. J Cell Biol. 135: 711-24. PMID: 8909545
  10. 运动神经轴突的神经丝依赖性径向生长和神经丝的轴突组织不需要神经丝重亚基（NF-H）或其磷酸化。  |  Rao, MV., et al. 1998. J Cell Biol. 143: 171-81. PMID: 9763429

订购信息

产品名称产品编号规格价格数量收藏夹

NF-H 抗体 (2D2)

sc-20014
200 µg/ml
RMB2377.00

I see that the sc-20014 has a concentration of 200 µg/ml and is priced at $316ea. But, how many ml are in "1 each"?

Asked by: Pammy
Thank you for your question. The volume is 1ml.
Answered by: BlakeJ
Date published: 2025-04-04

Are there any issues with using sc-20014: NF-H (2D2) mouse monoclonal primary antibody on mouse samples?

Asked by: Randy McDonald
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent,we recommend using a directly conjugated primary antibody. Please contact our special orders department for pricing and availability of sc-20014 conjugates.
Answered by: Technical Support
Date published: 2017-03-07
  • y_2025, m_8, d_30, h_9CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_20014, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 103ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Great reactiveI am going to try one Hope it works But I am not sure which one is better NF-L or NF-M?
Date published: 2019-02-07
Rated 4 out of 5 by from Strong band in WB in rat brain tissue extractStrong band in WB in rat brain tissue extract. -SCBT QC
Date published: 2015-03-05
Rated 4 out of 5 by from Positive signal in WB in human transfectedPositive signal in WB in human transfected 293T whole cell lysates. -SCBT QC
Date published: 2015-02-13
Rated 4 out of 5 by from Robust signal in WB in human transfectedRobust signal in WB in human transfected 293T whole cell lysates. -SCBT QC
Date published: 2013-02-25
  • y_2025, m_8, d_30, h_9
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_4
  • loc_zh_CN, sid_20014, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 7ms
  • REVIEWS, PRODUCT
NF-H 抗体 (2D2) is rated 4.3 out of 5 by 4.
  • y_2025, m_8, d_30, h_9
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_4
  • loc_zh_CN, sid_20014, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 106ms
  • REVIEWS, PRODUCT
021-6093-6350
访问 Santa Cruz Animal Health|访问 San Juan Ranch
Santa Cruz Biotechnology, Inc. 是生物医学研究市场产品开发的世界领导者。请拨打0086-021-60936350联系我们。
版权所有© 2007-2025 Santa Cruz Biotechnology, Inc. 保留所有权利。”Santa Cruz Biotechnology” 和Santa Cruz Biotechnology, Inc.的商标，”Santa Cruz Animal Health”, “San Juan Ranch”, “Supplement of Champions”, San Juan Ranch的商标，”UltraCruz”, “ChemCruz”, “ImmunoCruz”, “ExactaCruz”, 和 “EZ Touch”是Santa Cruz Biotechnology, Inc.的注册商标。所有商标均为其各自所有者的财产。