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Neutrophil Marker 抗体 (NIMP-R14): sc-59338

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说明书
  • Neutrophil Marker 抗体 NIMP-R14 是大鼠单克隆 IgG2bNeutrophil Marker抗体, 在98篇文献中引用,规格为100 µg/ml
  • 针对纯化的BALB/c mouse来源中性粒细胞
  • 推荐用于 mouse 来源的neutrophils IF, IHC(P) 和 FCM检测
  • 关于如何获取Neutrophil Marker (NIMP-R14): sc-59338免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前,我们还没有完成Neutrophil Marker 抗体 (NIMP-R14)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

中性粒细胞标记抗体(NIMP-R14)是一种IgG2b大鼠单克隆中性粒细胞标记抗体(也称为中性粒细胞标记抗体、嗜异性粒细胞标记抗体或髓样细胞分化中性粉红细胞标记抗体),可通过IF、IHC(P)和FCM检测小鼠来源的中性粒细胞标记蛋白。中性粒细胞标记抗体(NIMP-R14)可作为非偶联抗中性粒细胞标记抗体。中性粒细胞也称为中性粒细胞粒细胞,是最丰富的白细胞类型。作为哺乳动物免疫系统的组成部分,中性粒细胞负责防御细菌感染和其他微小炎症。中性粒细胞对细菌感染迅速作出反应,通常是免疫系统的第一反应。内皮肥大细胞和巨噬细胞表达大量细胞因子,立即吸引大量游走的中性粒细胞聚集在感染部位。单个中性粒细胞只能通过执行一个主要的吞噬事件来生存,利用其所有的能量储备进行强有力的"呼吸爆发"。此外,中性粒细胞在三种不同类型的颗粒中释放多种蛋白质:特异性颗粒、嗜天青颗粒和第三级颗粒。中性粒细胞的抗菌产品也可以破坏宿主组织。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Neutrophil Marker 抗体 (NIMP-R14) 参考文献:

  1. 与生病的笼友同居:对去甲肾上腺素代谢和中性粒细胞活性的影响  |  Alves, GJ., et al. 2006. Neurosci Res. 56: 172-9. PMID: 16971013
  2. 多发性骨髓瘤患者在接受大剂量化疗和自体造血干细胞移植后,服用 pegfilgrastim 后 G-CSF 血浆水平的持续升高可加快中性粒细胞的重建。  |  Fenk, R., et al. 2006. Exp Hematol. 34: 1296-302. PMID: 16982322
  3. 流感诱导的中性粒细胞功能障碍和中性粒细胞依赖性机制都会增加继发性肺炎链球菌感染的易感性。  |  McNamee, LA. and Harmsen, AG. 2006. Infect Immun. 74: 6707-21. PMID: 16982840
  4. CD69 在急性中性粒细胞介导的炎症中的作用。  |  Lamana, A., et al. 2006. Eur J Immunol. 36: 2632-8. PMID: 16983725
  5. Rho GTPase Rac1 对中性粒细胞迁移到肺部至关重要。  |  Filippi, MD., et al. 2007. Blood. 109: 1257-64. PMID: 16990606
  6. 肿瘤坏死因子-α对抗蛋白酶-3 或抗骨髓过氧化物酶抗体诱导的人中性粒细胞 NADPH- 氧化酶活性的引诱作用。  |  Reumaux, D., et al. 2006. J Leukoc Biol. 80: 1424-33. PMID: 16997860
  7. 脓毒症期间 C5a 对中性粒细胞凋亡的体内调控。  |  Guo, RF., et al. 2006. J Leukoc Biol. 80: 1575-83. PMID: 16997861

订购信息

产品名称产品编号规格价格数量收藏夹

Neutrophil Marker 抗体 (NIMP-R14)

sc-59338
100 µg/ml
RMB2377.00

Can this reagent be used for detection of neutrophils of rat ?

Asked by: frost504
Thank you for your question. This antibody is not currently recommended for detection of neutrophils in rat.
Answered by: Technical Support
Date published: 2019-06-16

Can anyone please provide the antigen retrieval (buffer) protocol for this antibody for IHC(P) staining? Neutrophil Marker (NIMP-R14): sc-59338

Asked by: Kishore_P
Thank you for your question. We recommend using sodium citrate buffer (pH 6.0) with heat treatment for antigen retrieval with this antibody, NIMP-R14. A link to our recommended protocol for IHC(P) is provided below for your reference. https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2018-04-17

What is the total volume provided of Neutrophil Marker Antibody (NIMP-R14): sc-59338?

Asked by: jenni
Thank you for your question. Neutrophil Marker Antibody (NIMP-R14): sc-59338 is provided as 100 µg in 1 ml total volume.
Answered by: Technical Support 12
Date published: 2017-01-09
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Rated 5 out of 5 by from Neutrophil marker antibodyIt really works well at IF staining for mouse lung tissues.
Date published: 2018-03-06
Rated 5 out of 5 by from Works greatUsed for IHC on paraffin sections of mouse cornea and it gave good staining with Nova Red dye and ABC kit.
Date published: 2017-02-01
Rated 5 out of 5 by from Great for mouse detectionA great antibody for detecting neutrophils in mouse samples and works great for immunostaining. It has been published with 10 times.
Date published: 2017-01-16
Rated 5 out of 5 by from Positive IHC data gathered with mice lungsPositive IHC data gathered with mice lungs -SCBT Publication Review
Date published: 2015-03-01
Rated 5 out of 5 by from Produced publishable IHCP data with mouseProduced publishable IHCP data with mouse brain and tongue - SCBT Publication Review
Date published: 2013-02-23
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Neutrophil Marker 抗体 (NIMP-R14) is rated 5.0 out of 5 by 5.
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