Date published: 2025-9-8

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neuropilin-2 抗体 (C-9): sc-13117

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说明书
  • neuropilin-2 抗体 C-9 是小鼠单克隆 IgG2b κ,neuropilin-2抗体, 在59篇文献中引用,规格为200 µg/ml
  • 免疫human物种的neuropilin-2的氨基酸560-858
  • neuropilin-2 抗体 (C-9) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 neuropilin-2
  • 抗neuropilin-2抗体(C-9)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取neuropilin-2 (C-9): sc-13117免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG2b BP-HRPm-IgGκ BP-HRP 是 neuropilin-2 抗体 (C-9) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与neuropilin-2 抗体 (C-9) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

神经丝蛋白-2抗体(C-9)是一种小鼠单克隆IgG2b kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)、免疫组织化学和酶联免疫吸附测定(ELISA)检测小鼠、大鼠和人类来源的神经丝蛋白-2。 酶联免疫吸附试验(ELISA)。神经丝蛋白-2抗体(C-9)有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和多种Alexa Fluor®结合物。神经丝蛋白-2是一种I型跨膜受体,在轴突生长和引导中起着至关重要的作用,是III类趋化因子和血管内皮生长因子(VEGF)的高亲和力受体。神经丝蛋白-2在调节生理途径(如血管生成和神经发育)方面尤为重要。已知神经丝蛋白-2会经历多唾液酸化,这是一种翻译后修饰,可增强与配体的相互作用并影响细胞信号传导的功能。神经丝蛋白-2在树突状细胞上的表达以及在静脉和淋巴内皮中的存在凸显了其在免疫反应和血管生物学中的重要性。相比之下,神经丝蛋白-1主要在动脉内皮中表达,表明这些蛋白质在血管系统中的功能存在差异。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

neuropilin-2 抗体 (C-9) 参考文献:

  1. 神经肽在生理和病理血管生成中的作用  |  Staton, CA., et al. 2007. J Pathol. 212: 237-48. PMID: 17503412
  2. [血管内皮生长因子受体在皮肤病中的表达研究进展]。  |  Yang, XH., et al. 2007. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 29: 279-82. PMID: 17536285
  3. 聚ialylated neuropilin-2 在人类树突状细胞表面表达并调节树突状细胞与 T 淋巴细胞的相互作用。  |  Curreli, S., et al. 2007. J Biol Chem. 282: 30346-56. PMID: 17699524
  4. 神经丝蛋白-2在免疫系统中的作用。  |  Schellenburg, S., et al. 2017. Mol Immunol. 90: 239-244. PMID: 28843905
  5. 抑制血管内皮生长因子与神经丝蛋白-2的结合可增强三阴性乳腺癌的化疗敏感性并抑制其转移。  |  Xu, Z., et al. 2023. Sci Transl Med. 15: eadf1128. PMID: 37134152
  6. 小鼠半aphorin D/collapsin是一个多样化基因家族的成员,可创建抑制轴突延伸的结构域。  |  Püschel, AW., et al. 1995. Neuron. 14: 941-8. PMID: 7748561
  7. Semaphorin III 可作为一种选择性趋光剂,对脊髓中的感觉投射进行模式化。  |  Messersmith, EK., et al. 1995. Neuron. 14: 949-59. PMID: 7748562
  8. 轴突导向:排斥生长锥的有力证据  |  Dodd, J. and Schuchardt, A. 1995. Cell. 81: 471-4. PMID: 7758101
  9. semaphorin基因编码一系列跨膜和分泌型生长锥导向分子。  |  Kolodkin, AL., et al. 1993. Cell. 75: 1389-99. PMID: 8269517
  10. 引导分子 semaphorin III 表达于脊髓和外周区域,这些区域被不断生长的感觉轴突所避开。  |  Wright, DE., et al. 1995. J Comp Neurol. 361: 321-33. PMID: 8543665
  11. Neuropilin 是轴突趋化素 Semaphorin III 的受体。  |  He, Z. and Tessier-Lavigne, M. 1997. Cell. 90: 739-51. PMID: 9288753
  12. Neuropilin 是一种 semaphorin III 受体。  |  Kolodkin, AL., et al. 1997. Cell. 90: 753-62. PMID: 9288754

订购信息

产品名称产品编号规格价格数量收藏夹

neuropilin-2 抗体 (C-9)

sc-13117
200 µg/ml
RMB2377.00

neuropilin-2 (C-9): m-IgG Fc BP-HRP 套装

sc-528261
200 µg Ab; 10 µg BP
RMB2662.00

neuropilin-2 (C-9): m-IgGκ BP-HRP 套装

sc-520594
200 µg Ab, 40 µg BP
RMB2662.00

neuropilin-2 (C-9): m-IgG2b BP-HRP 套装

sc-550015
200 µg Ab; 10 µg BP
RMB2662.00

neuropilin-2 抗体 (C-9) AC

sc-13117 AC
500 µg/ml, 25% agarose
RMB3129.00

neuropilin-2 抗体 (C-9) HRP

sc-13117 HRP
200 µg/ml
RMB2377.00

neuropilin-2 抗体 (C-9) FITC

sc-13117 FITC
200 µg/ml
RMB2482.00

neuropilin-2 抗体 (C-9) PE

sc-13117 PE
200 µg/ml
RMB2580.00

neuropilin-2 抗体 (C-9) Alexa Fluor® 488

sc-13117 AF488
200 µg/ml
RMB2685.00

neuropilin-2 抗体 (C-9) Alexa Fluor® 546

sc-13117 AF546
200 µg/ml
RMB2685.00

neuropilin-2 抗体 (C-9) Alexa Fluor® 594

sc-13117 AF594
200 µg/ml
RMB2685.00

neuropilin-2 抗体 (C-9) Alexa Fluor® 647

sc-13117 AF647
200 µg/ml
RMB2685.00

neuropilin-2 抗体 (C-9) Alexa Fluor® 680

sc-13117 AF680
200 µg/ml
RMB2685.00

neuropilin-2 抗体 (C-9) Alexa Fluor® 790

sc-13117 AF790
200 µg/ml
RMB2685.00

What is your recommended secondary for this mouse monoclonal antibody?

Asked by: Anna99
We recommend using our Mouse IgG kappa Binding Protein HRP, sc-516102. This is a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support 12
Date published: 2017-01-09
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Rated 5 out of 5 by from バックグラウンドも少なく、使いやすい抗体でした細胞上での発現確認(ウエスタンブロット)のため、本製品サンプルをオーダーしました。実際に使ってみたところ、目的のバンドをしっかりと検出出来ました。
Date published: 2020-05-31
Rated 4 out of 5 by from Works GreatTried the NRP2 antibody for looking at expression in HUVEC cells using western blot. Validated the bands with knockdown using siRNA.
Date published: 2017-12-13
Rated 4 out of 5 by from Quite goodSharp but several bands visible on WB in human neural stem cells
Date published: 2017-11-28
Rated 5 out of 5 by from Very good antibody IHCVery specific in IHC on paraffin sections from human fetal brain
Date published: 2017-06-14
Rated 5 out of 5 by from that is okNeurofilm proteins are type I transmembrane receptors that are involved in aspects of axonal growth and guidance and have been shown to be high affinity receptors for class III brain signaling proteins and vascular endothelial growth factors.
Date published: 2017-02-08
Rated 1 out of 5 by from Not working for IF in NRP2b overexpression HEKsThis antibody is not specific in immunofluorescence staining of HEK cells overexpressing flag-tagged NRP2b based on co-staining with anti-flag antibody. It also stains very differently from R&D antibody which works much better for my experiments. Fortunately, I got this antibody as a sample.
Date published: 2017-01-14
Rated 5 out of 5 by from Excellent productVery nice product for both western blot and IHC applications
Date published: 2017-01-06
Rated 5 out of 5 by from Strong DataGood cytoplasmic signal in human epidermal tissue in IHC(P)
Date published: 2016-12-23
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neuropilin-2 抗体 (C-9) is rated 4.3 out of 5 by 18.
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