Date published: 2025-9-8

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Neuritin 抗体 (B-9): sc-365538

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说明书
  • Neuritin 抗体 B-9 是小鼠单克隆 IgM κ,Neuritin抗体, 在4篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的Neuritin的N-terminus的氨基酸42-67之间
  • 推荐用于 mouse, rat 和 human 来源的Neuritin WB, IP, IF 和 ELISA检测; 也和以下物种反应,包括: 和 equine, canine, bovine and porcine
  • 关于如何获取Neuritin (B-9): sc-365538免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前,我们还没有完成Neuritin 抗体 (B-9)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

Neuritin抗体(B-9)是一种IgMκ小鼠单克隆Neuritin抗体(也称为Neuritin抗体),能够通过Western Blot(WB)、免疫沉淀(IP)、免疫荧光(IF)和酶联免疫吸附测定(ELISA)等方法检测小鼠、大鼠和人类来源的Neuritin蛋白。Neuritin抗体(B-9)以非偶联型抗Neuritin抗体形式供应。神经营养因子能够调节神经元在发育过程中的自然死亡。神经营养因子的原型是神经生长因子(NGF)。NGF是一种可溶性肽,能够促进交感神经节的生存和神经突起的生长。目前已经发现了三种结构上同源的其他神经营养因子,包括脑源性神经营养因子(BDNF)、神经营养因子-3(NT-3)和神经营养因子-4(NT-4,也被称为NT-5)。Neuritin是一种糖基磷脂酰肌醇锚定蛋白,由神经活动和BDNF及NT-3诱导产生。Neuritin在细胞外调节神经突起的生长,并在发育和成年神经系统中存在,表明它参与神经元的可塑性。除了BDNF能够诱导Neuritin外,研究表明,视觉皮层的光刺激也能同时诱导Neuritin和BDNF的产生。Neuritin似乎位于BDNF下游,可能介导BDNF的一些作用。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Neuritin 抗体 (B-9) 参考文献:

  1. 脊髓损伤后的神经元可塑性:鉴定驱动神经元突起生长的基因簇。  |  Di Giovanni, S., et al. 2005. FASEB J. 19: 153-4. PMID: 15522907
  2. 雄激素诱导的神经元外生是由运动神经元中的神经营养素介导的。  |  Marron, TU., et al. 2005. J Neurochem. 92: 10-20. PMID: 15606892
  3. CPG15在体内促进协调运动神经元轴突生长和神经肌肉突触发生。  |  Javaherian, A. and Cline, HT. 2005. Neuron. 45: 505-12. PMID: 15721237
  4. 神经营养因子的变化。  |  Thoenen, H. 1991. Trends Neurosci. 14: 165-70. PMID: 1713715
  5. 神经系统发育过程中的细胞死亡  |  Oppenheim, RW. 1991. Annu Rev Neurosci. 14: 453-501. PMID: 2031577
  6. 神经营养因子神经营养素的功能和相关信号传导途径。  |  Yao, JJ., et al. 2018. Acta Pharmacol Sin. 39: 1414-1420. PMID: 29595190
  7. 滤泡调节性 T 细胞产生神经肽来调节 B 细胞。  |  Gonzalez-Figueroa, P., et al. 2021. Cell. 184: 1775-1789.e19. PMID: 33711260
  8. 神经营养素抑制星形胶质细胞增生以改善糖尿病认知功能障碍  |  Zhang, Z., et al. 2021. J Mol Endocrinol. 66: 259-272. PMID: 33729996
  9. 与 CTP 融合可提高重组神经肽的稳定性。  |  Meng, P., et al. 2023. Protein Expr Purif. 212: 106344. PMID: 37567400
  10. 神经营养素在小鼠神经元发育中的作用  |  Klein, R. 1994. FASEB J. 8: 738-44. PMID: 8050673
  11. 脊椎动物进化过程中神经营养因子的保存。  |  Götz, R. and Schartl, M. 1994. Comp Biochem Physiol Pharmacol Toxicol Endocrinol. 108: 1-10. PMID: 8061955
  12. 神经营养素:一种由神经活动和神经营养素诱导的基因,可促进神经元的生成。  |  Naeve, GS., et al. 1997. Proc Natl Acad Sci U S A. 94: 2648-53. PMID: 9122250

订购信息

产品名称产品编号规格价格数量收藏夹

Neuritin 抗体 (B-9)

sc-365538
200 µg/ml
RMB2377.00

Neuritin (B-9) 中和勝肽

sc-365538 P
100 µg/0.5 ml
RMB511.00

Is there any validation for its use in ELISA? Thank you.

Asked by: PCGF
Thank you for your question. Based on our tests with this antibody, we recommend Anti-Neuritin Antibody (B-9): sc-365538 for detection of Neuritin of mouse, rat and human origin by WB, IP, IF and ELISA.
Answered by: Tech Support Europe
Date published: 2022-09-19

What application is the blocking peptide sc-365538 P appropriate for?

Asked by: DefinitelyNotMatt
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2020-07-30
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Rated 5 out of 5 by from easy got resultI use milk 5% as blocking agent for room temperature incubated for 1 hour(s) ,antibody diluted at 1:800,RT incubated1hour, goat anti mouse HRP secondary used from Jackson company, use ECL system for detection.I got the target band very easy by one time.
Date published: 2017-06-24
Rated 5 out of 5 by from SensitiveUsually we use it detect the Neuritin in rat, we use the dilution 1:1000 , Can get the desired results.
Date published: 2017-05-07
Rated 5 out of 5 by from happy result.We've used this product and obtained strong bands for WB, 1:800 for WB.
Date published: 2017-02-11
Rated 5 out of 5 by from Wide ReactivityRaised against a well conserved epitope, reactive with a wide variety of species including equine, bovine and porcine.
Date published: 2017-01-27
Rated 5 out of 5 by from Produced nice Western blot data of NeuritinProduced nice Western blot data of Neuritin expression in Daudi whole cell lysate. -SCBT QC
Date published: 2014-05-30
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Neuritin抗体 (B-9) is rated 5.0 out of 5 by 5.
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