Date published: 2025-9-8

021-6093-6350

SCBT Portrait Logo
Seach Input

NAT-10 抗体 (C-10): sc-271141

5.0(1)
寫評論提問

说明书
  • NAT-10抗体(C-10)是小鼠单克隆IgG1 (kappa轻链),规格为200 µg/ml
  • 针对NAT-10的内部区域human起源的肽图
  • 推荐用于 mouse, rat 和 human 来源的NAT-10 WB, IP, IF, IHC(P) 和 ELISA检测
  • 1 BP-HRP">m-IgG1 BP-HRP是NAT-10 Antibody (C-10) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂。该试剂现与NAT-10 Antibody (C-10) 打包提供(请参阅下面的订购信息)。

    快捷链接

    関連項目

    NAT-10(N-乙酰转移酶10)是一种属于UPF0202家族的核蛋白。它具有一个N-乙酰转移酶结构域,可能起到组蛋白乙酰转移酶的作用。 NAT10主要功能是调节端粒酶的活性。它在DNA损伤反应中上调,可能参与遗传毒性抗性和DNA修复。 NAT-10对刺激端粒酶产生的TERT启动子区域具有很高的结合潜力。这些功能表明人类端粒酶复合物具有多种功能,而不是特定的职责。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    NAT-10 抗体 (C-10) 参考文献:

    1. NAT10介导的mRNA N4-乙酰胞苷修饰促进膀胱癌进展。  |  Wang, G., et al. 2022. Clin Transl Med. 12: e738. PMID: 35522942
    2. 乙酰转移酶NAT10通过KIF23 mRNA的ac4C乙酰化调节Wnt/β-catenin信号通路,从而促进结直肠癌进展。  |  Jin, C., et al. 2022. J Exp Clin Cancer Res. 41: 345. PMID: 36522719
    3. NAT10的赖氨酸2-羟基异丁酰化以ac4C依赖的方式促进癌症转移。  |  Liao, L., et al. 2023. Cell Res. 33: 355-371. PMID: 36882514
    4. NAT10通过增强膀胱癌中与ac4C相关的DNA修复来驱动顺铂耐药性。  |  Xie, R., et al. 2023. Cancer Res. 83: 1666-1683. PMID: 36939377
    5. NAT10通过巨噬细胞中的NOX2-ROS-NF-κB通路调节LPS诱导的炎症反应。  |  Zhang, Z., et al. 2023. Biochim Biophys Acta Mol Cell Res. 1870: 119521. PMID: 37307924
    6. NAT10介导的ac4C tRNA修饰促进癌症中EGFR mRNA的翻译和吉非替尼抗性。  |  Wei, W., et al. 2023. Cell Rep. 42: 112810. PMID: 37463108
    7. NAT10介导的N4-乙酰胞苷mRNA修饰调节人类胚胎干细胞的自我更新。  |  Liu, R., et al. 2023. Nucleic Acids Res. 51: 8514-8531. PMID: 37497776
    8. NAT10/ac4C/FOXP1通过重新编程宫颈癌的糖酵解代谢促进恶性进展并促进免疫抑制。  |  Chen, X., et al. 2023. Adv Sci (Weinh). 10: e2302705. PMID: 37818745
    9. NAT10通过ac4C介导的转录调控参与心脏重塑。  |  Shi, J., et al. 2023. Circ Res. 133: 989-1002. PMID: 37955115
    10. NAT10相分离调节YTHDF1剪接以促进胃癌进展。  |  Liu, S., et al. 2024. Cancer Res. 84: 3207-3222. PMID: 39024555

    订购信息

    产品名称产品编号规格价格数量收藏夹

    NAT-10 抗体 (C-10)

    sc-271141
    200 µg/ml
    RMB2377.00

    NAT-10 (C-10): m-IgG1 BP-HRP 套装

    sc-542678
    200 µg Ab; 20 µg BP
    RMB2662.00

    NAT-10 (C-10) 中和勝肽

    sc-271141 P
    100 µg/0.5 ml
    RMB511.00

    What application is the blocking peptide sc-271141 P appropriate for?

    Asked by: Dr Ninau Qelp
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-25
    • y_2025, m_8, d_30, h_9CST
    • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasquestionsanswers, tq_1
    • loc_zh_CN, sid_271141, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getContent, 149ms
    • QUESTIONS, PRODUCT
    Rated 5 out of 5 by from Beautiful immunoperoxidase nuclear and nucleolarBeautiful immunoperoxidase nuclear and nucleolar staining in formalin fixed, paraffin-embedded human esophagus tissue. -SCBT QC
    Date published: 2015-05-15
    • y_2025, m_8, d_30, h_9
    • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasreviews, tv_0, tr_1
    • loc_zh_CN, sid_271141, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getReviews, 13ms
    • REVIEWS, PRODUCT
    NAT-10 抗体 (C-10) is rated 5.0 out of 5 by 1.
    • y_2025, m_8, d_30, h_9
    • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasreviews, tv_0, tr_1
    • loc_zh_CN, sid_271141, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getAggregateRating, 102ms
    • REVIEWS, PRODUCT