Naphazoline Nitrate (CAS 5144-52-5)

物理状态 :

Solid

溶解度 :

Soluble in water (slightly), and alcohol. Insoluble in ether.

保存 :

Store at room temperature

熔点 :

168-170° C (lit.)

沸点 :

440.5° C at 760 mmHg (Predicted)

折射率 :

n²⁰_D 1.64 (Predicted)

IC50 :

Adrenergic receptor α-2: IC₅₀ = 1.1 pM (human); Adrenergic receptor α-2: IC₅₀ = 4.8 nM (rat); Adrenergic receptor α-1: EC₅₀50 = 12 nM (rat); Adrenergic receptor α-1: IC₅₀ = 410 nM (rat); Plasmodium falciparum: IC₅₀ = 10 µM

Ki 数据 :

Adrenergic receptor α-2: K_i= 5.7 nM (rat); Nischarin: K_i= 121.6 nM (human); Displacement of [125I]PIC from human α2 adrenoceptors expressed in CHO cells: K_i= 147.1 nM

德国水公害等级 :

3

RTECS :

NJ4376000

PubChem CID :

MDL 号码 :

MFCD00014316

EC号码 :

225-915-4

Beilstein 注册 :

3779329

SMILES :

C1CN=C(N1)CC2=CC=CC3=CC=CC=C32.[N+](=O)(O)[O-]