N-Desmethyl Escitalopram (CAS 144025-14-9)

TEST CONDITIONS

HPLC Conditions: The product was examined by analytical HPLC using a diode array detector. Column: Chromolith performance C18 4.6 mm X 100 mm; Flow rate: 1 ml/min; Solvents: water (0.1% TFA) and acetonitrile; Gradient: 5% to 100% acetonitrile over 20 min, return to 95% water over 10 minutes. The chromatogram used for purity and homogeneity assessment was the summed absorbance between 220 nm and 270 nm. Purity was determined as the area percent of the major peak after integration of any impurities judged to be authentic by the analyst. 1H-NMR conditions: Proton magnetic resonance spectra were run in deuterio-DMSO at 300 MHz. The NMR indicates the presence of 2.6 wt% residual tetrahydrofuran that was not removed after drying at room temperature under vacuum for 4 hours.Exp. Date: 1/9/2024