Date published: 2025-9-7

021-6093-6350

SCBT Portrait Logo
Seach Input

Munc13-4 抗体 (C-12): sc-271301

5.0(1)
寫評論提問

说明书
  • Munc13-4抗体(C-12)是小鼠单克隆IgG2a (kappa轻链),规格为200 µg/ml
  • 免疫原氨基酸序列136-285位于human物种的Munc13-4的N-terminus附近
  • 推荐用于 human 来源的Munc13-4 WB, IP, IF 和 ELISA检测
  • m-IgG Fc BP-HRP2a BP-HRP">m-IgG2a BP-HRPm-IgGκ BP-HRP是Munc13-4 Antibody (C-12) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Munc13-4 Antibody (C-12) 打包提供(请参阅下面的订购信息)。

    快捷链接

    関連項目

    Munc13-4是Munc13家族的一员,与Munc13-1是同源物。Munc13-4缺乏其他Munc13家族成员中存在的C1结构域和N端延伸。它是一种外周膜、GTP-Rab 27a结合蛋白。Munc13-4具有普遍的组织分布,然而,与相关蛋白质Munc13-1、-2和-3不同的是,Munc13-4主要在神经系统外表达。在肺的粘液杯状细胞和肺泡II型细胞,以及细胞毒性T淋巴细胞和肥大细胞中,已经观察到Munc13-4的高表达水平。Munc13-4定位于分泌型溶酶体。Munc13-4的过度表达增强了肥大细胞分泌型溶酶体的脱粒,这表明它正向调节分泌型溶酶体融合和外排。Munc13-4的突变会导致家族性噬血细胞性淋巴组织细胞增多症亚型3。

    仅限研究使用。不适用于诊断和治疗用途。

    订购信息

    产品名称产品编号规格价格数量收藏夹

    Munc13-4 抗体 (C-12)

    sc-271301
    200 µg/ml
    RMB2377.00

    Munc13-4 (C-12): m-IgG Fc BP-HRP 套装

    sc-537605
    200 µg Ab; 10 µg BP
    RMB2662.00

    Munc13-4 (C-12): m-IgGκ BP-HRP 套装

    sc-534920
    200 µg Ab; 40 µg BP
    RMB2662.00

    Munc13-4 (C-12): m-IgG2a BP-HRP 套装

    sc-548064
    200 µg Ab; 10 µg BP
    RMB2662.00

    What is the differences between this two products? Munc13-4 Antibody (C-12): sc-271301 and Munc13-4 Antibody (C-2): sc-271300? Which one should I choose for detection of UNC13D in NK cells??

    Asked by: Verna233
    Thank you for your question. The IgG2a Munc13-4 Antibody (C-12): sc-271301 was raised against amino acids 136-285 mapping near the N-terminus of Munc13-4 of human origin and is recommended for detection of Munc13-4 of human origin by WB, IP, IF and ELISA. The IgG1 Munc13-4 Antibody (C-2) was raised against the same amino acid sequence, but is also recommended for detection of Munc13-4 of human origin by IHC(P). They differ in their respective isotypes and recommeded applications and are otherwise quite similar. Either antibody is suitable for detection of human Munc13-4.
    Answered by: Tech Support Europe
    Date published: 2019-11-11

    What is the recommended starting dilution for Western blot for Munc13-4 (C-12): sc-271301 monoclonal antibody?

    Asked by: jerojero
    Thank you for your question. The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, can be found in the “datasheet” link at the top of the product page, for which I have provided the link: https://datasheets.scbt.com/sc-271301.pdf If you have any further questions or concerns, please contact our Technical Service department by calling 800-457-3801 option 2, emailing [email protected], or using the Live Chat function on our website.
    Answered by: Technical Support
    Date published: 2017-03-01
    • y_2025, m_9, d_7, h_4CST
    • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasquestionsanswers, tq_2
    • loc_zh_CN, sid_271301, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getContent, 103ms
    • QUESTIONS, PRODUCT
    Rated 5 out of 5 by from Good Western blot data of Munc13Good Western blot data of Munc13-4 expression in non-transfected and human Munc13-4 transfected 293T whole cell lysates. -SCBT QC
    Date published: 2014-10-17
    • y_2025, m_9, d_7, h_4
    • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasreviews, tv_0, tr_1
    • loc_zh_CN, sid_271301, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getReviews, 12ms
    • REVIEWS, PRODUCT
    Munc13-4 抗体 (C-12) is rated 5.0 out of 5 by 1.
    • y_2025, m_9, d_7, h_4
    • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
    • cp_1, bvpage1
    • co_hasreviews, tv_0, tr_1
    • loc_zh_CN, sid_271301, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getAggregateRating, 114ms
    • REVIEWS, PRODUCT