Date published: 2026-10-20

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Mucin 1/MUC1 抗体 (H-6): sc-25274

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说明书
  • Mucin 1/MUC1抗体(H-6)是小鼠单克隆IgG2a κ, 在3篇文献中引用,规格为200 µg/ml
  • 在C-terminus的Mucin 1的human起源
  • 推荐用于 human 来源的Mucin 1 WB, IP, IF, IHC(P) 和 ELISA检测
  • 看 Mucin 1/MUC1 (VU4H5): sc-7313,可查看有标记的 Mucin 1/MUC1 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP、 2a BP-HRP">m-IgG2a BP-HRP和m-IgGκ BP-HRP是Mucin 1/MUC1 Antibody (H-6) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂。这些试剂现与Mucin 1/MUC1 Antibody (H-6) 打包提供(请参阅下面的订购信息)。
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黏蛋白是一类高度糖基化的分泌蛋白,其基本结构由数量可变的串联重复序列(VNTRs)编码而成,其中Mucin 1为60个碱基对,Mucin 2为69个碱基对,Mucin 3为51个碱基对。重复数量具有高度多态性,并因等位基因不同而不同。Mucin 1蛋白除了分泌形式外,还以I型膜蛋白的形式表达。Mucin 1在乳腺癌等上皮肿瘤中异常表达。Mucin 2覆盖肠道和气道的上皮,与结肠肿瘤有关。Mucin 3是各种粘液凝胶的主要成分,在正常细胞和肿瘤细胞中广泛表达。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Mucin 1/MUC1 抗体 (H-6) 参考文献:

  1. 粘蛋白-1是柯萨奇病毒B3诱导的胰腺炎炎症的必需物质  |  Liu, X., et al. 2019. Sci Rep. 9: 10656. PMID: 31337812
  2. 抑制T细胞免疫球蛋白和粘蛋白-1(TIM-1)可防止脑缺血再灌注损伤。  |  Zheng, Y., et al. 2019. Cell Commun Signal. 17: 103. PMID: 31438964
  3. 基于Mucin-1共轭聚酰胺胺的纳米颗粒在图像引导下向乳腺癌患者递送吉非替尼  |  Nabi, PN., et al. 2021. Int J Biol Macromol. 174: 185-197. PMID: 33516855
  4. 粘蛋白1调节头颈部癌细胞的缺氧反应。  |  Utispan, K. and Koontongkaew, S. 2021. J Pharmacol Sci. 147: 331-339. PMID: 34663515
  5. Mucin 1通过GSK3β/Keap1-Nrf2-GPX4通路抑制铁蛋白沉积并使维生素E敏感以缓解败血症诱发的急性肺损伤  |  Wang, YM., et al. 2022. Oxid Med Cell Longev. 2022: 2405943. PMID: 35910848
  6. 未经治疗的中国患者血清半乳糖凝集素-3和粘蛋白-1(CA15-3)与肾功能的关系。  |  Huang, QF., et al. 2023. Am J Hypertens. 36: 176-182. PMID: 36226892
  7. 表达 PD-1-CD28 开关受体的抗粘蛋白 1 嵌合抗原受体 T 细胞对胆管癌细胞的细胞毒性活性。  |  Supimon, K., et al. 2023. Cytotherapy. 25: 148-161. PMID: 36396553
  8. 粘蛋白1表达与淋巴结转移、微转移和食管鳞状细胞癌患者预后不良的相关性。  |  Yang, F., et al. 2023. Arch Med Sci. 19: 638-644. PMID: 37313197
  9. 探查乳腺癌细胞外囊泡中异常糖基化的黏蛋白1。  |  Saroj, S., et al. 2023. ACS Appl Bio Mater. 6: 4944-4951. PMID: 37824707
  10. Mucin-1靶向嵌合抗原受体T细胞能有效安全地控制免疫功能正常宿主的实体瘤  |  Zhou, R., et al. 2024. J Immunother. 47: 77-88. PMID: 38270462

订购信息

产品名称产品编号规格价格数量收藏夹

Mucin 1/MUC1 抗体 (H-6)

sc-25274
200 µg/ml
CNY2422.00

Mucin 1/MUC1 (H-6): m-IgG Fc BP-HRP 套装

sc-536698
200 µg Ab; 10 µg BP
CNY2715.00

Mucin 1/MUC1 (H-6): m-IgGκ BP-HRP 套装

sc-533858
200 µg Ab; 40 µg BP
CNY2715.00

Mucin 1/MUC1 (H-6): m-IgG2a BP-HRP 套装

sc-547849
200 µg Ab; 10 µg BP
CNY2715.00

I am using Mucin 1 (H-6): sc-25274 monoclonal antibody to stain paraffin embedded tissue. Do you recommend antigen retrieval when using this antibody?

Asked by: jenniferc
We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by JT from WB: Single clean band in DU 145 whole cell lysateWB: Single clean band in DU 145 whole cell lysate. -SCBT QC
Date published: 2015-04-14
Rated 5 out of 5 by MS from IF publication with human mesenchymal/stromalIF publication with human mesenchymal/stromal cells
Date published: 2015-03-02
Rated 5 out of 5 by SS from Worked well for Western with human peripheralWorked well for Western with human peripheral blood samples. -SCBT QC
Date published: 2015-01-29
Rated 5 out of 5 by CJ from Great IHC data with paraffinGreat IHC data with paraffin-embedded human upper stomach tissue. -SCBT QC
Date published: 2014-01-30
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Mucin 1/MUC1 抗体 (H-6) is rated 5.0 out of 5 by 4.
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