Date published: 2025-9-7

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Msi1 抗体 (69-Q): sc-135721

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说明书
  • Msi1 抗体 69-Q 是小鼠单克隆 IgG2a κ,Msi1抗体, 在11篇文献中引用,规格为100 µg/ml
  • 针对氨基酸1-87的,代表Msi1的human起源的N-terminal区域
  • 推荐用于 mouse, rat 和 human 来源的Msi1 WB, IP, IF, IHC(P) 和 ELISA检测
  • 关于如何获取Msi1 (69-Q): sc-135721免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG2a BP-HRPm-IgGκ BP-HRP 是 Msi1 抗体 (69-Q) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与Msi1 抗体 (69-Q) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

Msi1抗体(69-Q)是一种IgG2a κ小鼠单克隆Msi1抗体(也称为Msi1抗体),可通过WB、IP、IF、IHC(P)和ELISA检测小鼠、大鼠和人的Msi1蛋白。Msi1抗体(69-Q)为非偶联的抗Msi1抗体。Musashi1(Msi1)是一种在神经祖细胞和神经干细胞中表达的RNA结合蛋白。Msi1是果蝇Musashi的哺乳动物同源物。编码人类Msi1的基因编码一个由362个氨基酸组成的蛋白质。在小鼠胚胎神经祖细胞中,Msi1定位于细胞质中,并在分化过程中被下调。Msi1与NUMB结合,NUMB编码一种膜相关的Notch信号拮抗剂。Msi1似乎在中枢神经系统干细胞群的增殖和维持中发挥作用。除了作为正常人脑中神经祖细胞的标志物外,Msi1还是人类胶质瘤的标志物。在大鼠中,Msi1在睾丸的Sertoli细胞和卵巢的颗粒细胞中表达。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Msi1 抗体 (69-Q) 参考文献:

  1. Musashi1:中枢神经系统祖细胞(包括神经干细胞)的进化保守标记。  |  Kaneko, Y., et al. 2000. Dev Neurosci. 22: 139-53. PMID: 10657706
  2. 神经RNA结合蛋白Musashi1通过与其mRNA相互作用,对哺乳动物numb基因的表达进行翻译调控。  |  Imai, T., et al. 2001. Mol Cell Biol. 21: 3888-900. PMID: 11359897
  3. Musashi1是一种进化保守的神经RNA结合蛋白,是人类胶质瘤细胞的多功能标记物,可确定其细胞起源, 恶性程度和增殖活性。  |  Kanemura, Y., et al. 2001. Differentiation. 68: 141-52. PMID: 11686236
  4. RNA 结合蛋白 Musashi1 从胎儿期到成年期都在大鼠睾丸的睾丸细胞中表达。  |  Saunders, PT., et al. 2002. Biol Reprod. 66: 500-7. PMID: 11804968
  5. RNA结合蛋白Musashi家族:通过靶向干扰和反义消融揭示中枢神经系统干细胞和上皮细胞亚群的作用。  |  Sakakibara, S., et al. 2002. Proc Natl Acad Sci U S A. 99: 15194-9. PMID: 12407178
  6. 人类武藏同源物 1(MSI1)基因编码武藏/Nrp-1 的同源物,这是一种神经 RNA 结合蛋白,可能在中枢神经系统干细胞和神经祖细胞中表达。  |  Good, P., et al. 1998. Genomics. 52: 382-4. PMID: 9790759

订购信息

产品名称产品编号规格价格数量收藏夹

Msi1 抗体 (69-Q)

sc-135721
100 µg/ml
RMB2504.00

Msi1 (69-Q): m-IgG Fc BP-HRP 套装

sc-537370
100 µg Ab; 10 µg BP
RMB2662.00

Msi1 (69-Q): m-IgGκ BP-HRP 套装

sc-534618
100 µg Ab; 40 µg BP
RMB2662.00

Msi1 (69-Q): m-IgG2a BP-HRP 套装

sc-547998
100 µg Ab; 10 µg BP
RMB2662.00

Can sc-135721: Msi1 (69-Q) monoclonal antibody be used to stain 4% paraformaldehyde-fixed, frozen mouse brain tissue sections?

Asked by: Anthea H
Thank you for your question. Yes, this antibody should work with that application, especially when using with a corresponding isotype specific binding protein. A link to our binding proteins is provided below. https://www.scbt.com/browse/mouse-igg-binding-proteins/_/N-130b1ry
Answered by: Santa Cruz TS
Date published: 2021-08-03

Can sc-135721: Msi1 (69-Q) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: jenniferc
Thank you for your question. Yes, sc-135721: Msi1 (69-Q) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-03-24
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Rated 5 out of 5 by from an excellent reagent for p.wax sectionsThis ab is an excellent reagent for p.wax sections. I have not yet been able to find any other anti Mus-1 Ab that gives such good results.
Date published: 2017-02-13
Rated 5 out of 5 by from Great productThe Msi1 Antibody (69-Q): sc-135721 works very well for immunohistochemistry studies with formalin fixed, paraffin-embedded tissue sections, showing nuclear localization. This antibody has also been cited several times for further verification.
Date published: 2017-01-24
Rated 5 out of 5 by from Produced beautiful immunoperoxidase nuclearProduced beautiful immunoperoxidase nuclear staining in formalin-fixed, paraffin-embedded human placenta tissue. -SCBT QC
Date published: 2015-05-05
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Msi1 抗体 (69-Q) is rated 5.0 out of 5 by 4.
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