Date published: 2025-9-7

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MOBP 抗体 (4C2): sc-517016

5.0(1)
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说明书
  • MOBP 抗体 4C2 是小鼠单克隆 IgG1 (kappa轻链),MOBP抗体,规格为100 µg/ml
  • 免疫human物种的代表全长MOBP的氨基酸1-81
  • 推荐用于 mouse, rat 和 human 来源的MOBP WB, IP 和 ELISA检测
  • 目前,我们还没有完成MOBP 抗体 (4C2)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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    関連項目

    MOBP抗体(4C2)是一种小鼠单克隆IgG1κ轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)和酶联免疫吸附测定(ELISA)检测小鼠、大鼠和人源的MOBP蛋白。抗MOBP抗体(4C2)以非结合形式提供。编码MOBP(髓磷脂相关性少突胶质细胞碱性蛋白)的基因位于3p22.2染色体上,是中枢神经系统髓磷脂鞘的重要组成部分。MOBP在髓磷脂的结构完整性中发挥着重要作用,而髓磷脂对于电脉冲沿神经纤维的正确传导至关重要。MOBP有多种剪接变体,包括MOBP-71、MOBP-81A、MOBP-99和MOBP-169,它们含有外显子8b,并专门定位于髓鞘组装部位,有助于髓鞘的形成。相比之下,MOBP-69、MOBP-81B和MOBP-170等变异体缺少外显子8b,保留在少突胶质细胞体中,可能具有调节功能。MOBP在多发性硬化症等脱髓鞘疾病中的参与凸显了其重要性,也凸显了其作为治疗干预靶标的潜力。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    MOBP 抗体 (4C2) 参考文献:

    1. 有证据表明,拟议的新型人类 '神经激肽-4 '受体与人类神经激肽-3受体在药理上相似,但并非源自人类。  |  Sarau, HM., et al. 2000. Mol Pharmacol. 58: 552-9. PMID: 10953048
    2. 健康和发炎人体肠道中的物质 P(神经激肽-1)和神经激肽 A(神经激肽-2)受体基因和蛋白表达。  |  Renzi, D., et al. 2000. Am J Pathol. 157: 1511-22. PMID: 11073811
    3. 物质P(SP)介导骨髓基质中干细胞因子和白细胞介素-1的产生:这些细胞因子在SP受体表达和诱导中的潜在自调节作用。  |  Rameshwar, P. and Gascón, P. 1995. Blood. 86: 482-90. PMID: 7541664
    4. 速激肽对造血的调节作用  |  Rameshwar, P. and Gascón, P. 1997. Acta Haematol. 98: 59-64. PMID: 9286300
    5. 大鼠脊髓中 NK-3 受体的免疫电镜定位。  |  Zerari, F., et al. 1997. Neuroreport. 8: 2661-4. PMID: 9295096

    订购信息

    产品名称产品编号规格价格数量收藏夹

    MOBP 抗体 (4C2)

    sc-517016
    100 µg/ml
    RMB2377.00

    I have tried to use it in 1:200 dilution and I can not see any band. I have tried in a lisate of proteins from cells and also from tissue. What can I do?

    Asked by: adhara
    Thank you for your question. Please contact technical service directly for troubleshooting advice with your experiment. Then we can see what the best solution for you would be. Thanks!
    Answered by: Tech Support Europe
    Date published: 2021-08-16

    For Western Blot, is it recommended to use denatured or non-denatured conditions with MOBP (4C2): sc-517016 antibody?

    Asked by: Cweed
    Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
    Answered by: Technical Support
    Date published: 2017-03-27
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    Rated 5 out of 5 by from Good for Western blotAntibody detects human recombinant MOBP and MOBP transfected lysate by Western blot. -SCBT QC
    Date published: 2023-09-14
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    MOBP 抗体 (4C2) is rated 5.0 out of 5 by 1.
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