Date published: 2025-9-6

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Metallothionein 3 抗体 (1F11): sc-293488

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说明书
  • Metallothionein 3 抗体 1F11 是小鼠单克隆 IgG2b (kappa轻链),Metallothionein 3抗体,规格为100 µg/ml
  • 免疫human物种的代表全长Metallothionein 3的氨基酸1-68
  • 推荐用于 human 来源的Metallothionein 3 WB, IP 和 ELISA检测
  • 关于如何获取Metallothionein 3 (1F11): sc-293488免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgGκ BP-HRP是Metallothionein 3 Antibody (1F11) 适用于 WB 应用。 的首选辅助检测试剂,这些试剂现与Metallothionein 3 Antibody (1F11) 打包提供(请参阅下面的订购信息)。

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    関連項目

    金属硫蛋白3抗体(1F11)是一种小鼠单克隆IgG2b kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)和酶联免疫吸附测定(ELISA)检测人类金属硫蛋白3蛋白。抗金属硫蛋白3抗体(1F11)以非结合形式提供。金属硫蛋白3(Metallothionein 3)也称为MT-3或GIFB(生长抑制因子),是一种68个氨基酸的蛋白质,属于1型家族和金属硫蛋白超家族。金属硫蛋白3在中枢神经系统,特别是大脑中起着至关重要的作用,在星形胶质细胞中表达量很高。金属硫蛋白3对于神经保护至关重要,因为它有助于减轻氧化应激和金属离子毒性,而氧化应激和金属离子毒性是神经退行性疾病的重要因素。值得注意的是,阿尔茨海默氏症患者大脑中的金属硫蛋白3表达减少,这表明其在该疾病的病理生理学中可能起着重要作用。此外,金属硫蛋白以结合重金属而闻名,从而为细胞提供保护,使其免受镉、汞和铜毒性的影响。金属硫蛋白3在心脏、肝脏、肾脏、乳房和睾丸等各种组织中的广泛表达,凸显了金属硫蛋白3在细胞生长、修复和分化中的重要性。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    Metallothionein 3 抗体 (1F11) 参考文献:

    1. 未分化鼻咽癌中的浸润淋巴细胞缺乏金属硫蛋白表达。  |  Jayasurya, A., et al. 2000. Cancer Lett. 155: 99-104. PMID: 10814885
    2. 金属硫蛋白-I/II无效小鼠比野生型小鼠对长期口服或注射无机砷的肝毒性和肾毒性作用更敏感。  |  Liu, J., et al. 2000. Toxicol Sci. 55: 460-7. PMID: 10828279
    3. 金属硫蛋白抑制缺铜小鼠心肌凋亡:心房利钠肽的作用  |  Kang, YJ., et al. 2000. Lab Invest. 80: 745-57. PMID: 10830785
    4. 硫代乙酰胺中毒大鼠肝脏金属硫蛋白的表达  |  Theocharis, SE., et al. 2000. Pathol Res Pract. 196: 313-9. PMID: 10834388
    5. 诱导金属硫蛋白合成并保持长期肾移植大鼠的睾丸功能  |  Cai, L., et al. 2000. Urol Res. 28: 97-103. PMID: 10850631
    6. 乳腺癌组织细胞组分中的金属硫蛋白水平。  |  Floriañczyk, B. and Grzybowska, L. 2000. Acta Oncol. 39: 141-3. PMID: 10859002
    7. 子宫内膜病变中金属硫蛋白的免疫组织化学定位。  |  Ioachim, EE., et al. 2000. J Pathol. 191: 269-73. PMID: 10878548
    8. 一种新型铜特异性金属硫蛋白和两种镉诱导型金属硫蛋白的 cDNAs 克隆和测序。  |  Syring, RA., et al. 2000. Comp Biochem Physiol C Toxicol Pharmacol. 125: 325-32. PMID: 11790353
    9. 金属硫蛋白基因家族中的脑特异性成员 MT-III。  |  Palmiter, RD., et al. 1992. Proc Natl Acad Sci U S A. 89: 6333-7. PMID: 1631128
    10. 阿尔茨海默病大脑中缺乏的生长抑制因子是一种 68 个氨基酸的金属硫蛋白样蛋白。  |  Uchida, Y., et al. 1991. Neuron. 7: 337-47. PMID: 1873033

    订购信息

    产品名称产品编号规格价格数量收藏夹

    Metallothionein 3 抗体 (1F11)

    sc-293488
    100 µg/ml
    RMB2377.00

    Metallothionein 3 (1F11): m-IgG Fc BP-HRP 套装

    sc-537753
    100 µg Ab; 10 µg BP
    RMB2662.00

    Metallothionein 3 (1F11): m-IgGκ BP-HRP 套装

    sc-535120
    100 µg Ab; 40 µg BP
    RMB2662.00

    Could we detect Metallothionein 1a protein using this antibody?

    Asked by: netlink
    Thank you for your question. No, this antibody is specific for Metallothionein 3.
    Answered by: Technical Support
    Date published: 2019-01-25

    For Western Blot, is it recommended to use denatured or non-denatured conditions with Metallothionein 3 (1F11): sc-293488 antibody?

    Asked by: DefinitelyNotMatt
    Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
    Answered by: Technical Support
    Date published: 2017-03-27
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    Rated 5 out of 5 by from Good choice for Western BlotThis antibody detects a strong band at the expected molecular weight in human brain tissue extract -SCBT QC
    Date published: 2023-09-14
    Rated 5 out of 5 by from Highly specific antibody great for ELISAThis antibody was tested against several structurally related forms of Metallothioneins and found to be highly specific for human MT3, with no cross reactivity toward other MT isoforms for MT1 and MT2.
    Date published: 2020-07-14
    Rated 5 out of 5 by from Great antibodyGreat antibody, with an excellent signal/noise ratio. Suitable for WB and IP.
    Date published: 2019-07-19
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    Metallothionein 3 抗体 (1F11) is rated 5.0 out of 5 by 3.
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