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Mesothelin 抗体 (G-4): sc-166125

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说明书
  • Mesothelin抗体(G-4)是小鼠单克隆IgG2b (kappa轻链),规格为200 µg/ml
  • 免疫原氨基酸序列291-575位于mouse物种的Mesothelin的C-terminus附近
  • 推荐用于 mouse, rat 和 human 来源的Mesothelin WB, IP, IF 和 ELISA检测
  • 看 Mesothelin (K1): sc-33672,可查看有标记的 Mesothelin 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 2b BP-HRP">m-IgG2b BP-HRPm-IgGκ BP-HRP是Mesothelin Antibody (G-4) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Mesothelin Antibody (G-4) 打包提供(请参阅下面的订购信息)。

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    関連項目

    间皮素是一种与糖磷脂酰肌醇相连的细胞表面分子,在体腔的间皮细胞层和许多肿瘤细胞中表达。间皮素是人体卵巢癌和间皮瘤表面的肿瘤抗原。间皮素的免疫反应性在卵巢癌(浆液性乳头状、子宫内膜样和未分化)和胰腺癌中较高,而在子宫内膜腺癌、肺癌和胃/食管癌中较少见。在成年小鼠组织中,间皮素转录本存在于肺、心、脾、肝、肾和睾丸中。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    Mesothelin 抗体 (G-4) 参考文献:

    1. 将间皮素作为嵌合抗原受体修饰 T 细胞抗癌疗法的靶细胞。  |  O'Hara, M., et al. 2016. Immunotherapy. 8: 449-60. PMID: 26973126
    2. 间皮素在胃肠癌中的表达对临床的影响。  |  Einama, T., et al. 2016. World J Gastrointest Pathophysiol. 7: 218-22. PMID: 27190694
    3. 包膜生长因子和间皮素:肝内胆管癌恶性进展的潜在预测因子  |  Mandrekar, P. and Cardinale, V. 2018. Hepatol Commun. 2: 481-483. PMID: 29761164
    4. 针对卵巢癌的间皮素。  |  Ghafoor, A., et al. 2018. Oncotarget. 9: 36050-36051. PMID: 30546824
    5. 针对急性髓性白血病间皮素的免疫疗法。  |  Wang, Q. and Gong, R. 2022. J Leukoc Biol. 112: 813-821. PMID: 35946307
    6. 中皮素在胆汁淤积性肝损伤中激活门静脉成纤维细胞的作用  |  Nishio, T., et al. 2022. Biology (Basel). 11: PMID: 36358290
    7. ZFP36干扰不足以增强间皮素靶向人类CAR-T细胞的功能。  |  Mai, D., et al. 2024. Sci Rep. 14: 3113. PMID: 38326511
    8. 间皮素-黏蛋白-16/CA125相互作用的结构阐释。  |  Rupert, PB., et al. 2024. Structure. 32: 1049-1054.e2. PMID: 38703776
    9. 针对结直肠癌的抗内皮素 CAR-NK 免疫疗法的再利用。  |  Torchiaro, E., et al. 2024. J Transl Med. 22: 1100. PMID: 39627822

    订购信息

    产品名称产品编号规格价格数量收藏夹

    Mesothelin 抗体 (G-4)

    sc-166125
    200 µg/ml
    RMB2377.00

    Mesothelin (G-4): m-IgGκ BP-HRP 套装

    sc-534715
    200 µg Ab; 40 µg BP
    RMB2662.00

    Mesothelin (G-4): m-IgG2b BP-HRP 套装

    sc-549288
    200 µg Ab; 10 µg BP
    RMB2662.00

    Are there any issues with using sc-166125: Mesothelin (G-4) mouse monoclonal primary antibody on mouse samples?

    Asked by: AbPolly
    Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent,we recommend using a directly conjugated primary antibody. Please contact our special orders department for pricing and availability of sc-166125 conjugates.
    Answered by: Technical Support
    Date published: 2017-03-07
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    Rated 5 out of 5 by from Nice Western blot data of Mesothelin expressionNice Western blot data of Mesothelin expression in non-transfected and mouse Mesothelin transfected 293T whole cell lysates. -SCBT QC
    Date published: 2014-07-01
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    Mesothelin 抗体 (G-4) is rated 5.0 out of 5 by 1.
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