Date published: 2025-9-8

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Mesothelin 抗体 (G-1): sc-271540

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说明书
  • Mesothelin抗体(G-1)是小鼠单克隆IgG1 κ, 在4篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列295-574位于human物种的Mesothelin的C-terminus附近
  • Mesothelin 抗体 (G-1) 推荐用于WB, IP, IF, IHC(P) 和 ELISA,检测human 来源的 Mesothelin
  • 抗Mesothelin抗体(G-1)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Mesothelin (G-1): sc-271540免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgG1 BP-HRP 是 Mesothelin 抗体 (G-1) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与Mesothelin 抗体 (G-1) 组合成套装提供。 (请参阅下面的订购信息)。

快捷链接

関連項目

间皮素抗体(G-1)是一种IgG1κ型小鼠单克隆抗体,通过WB、IP、IF、IHC(P)和ELISA检测来自人类的间皮素。间皮素抗体(G-1)既可以是非偶联的抗间皮素抗体形式,也可以是多种偶联形式的抗间皮素抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。间皮素是一种与糖磷脂酰肌醇相连的细胞表面分子,在体腔的间皮细胞层和许多肿瘤细胞中表达。间皮素是人体卵巢癌和间皮瘤表面的肿瘤抗原。间皮素的免疫反应性在卵巢癌(浆液性乳头状、子宫内膜样和未分化)和胰腺癌中较高,而在子宫内膜腺癌、肺癌和胃/食管癌中较少见。在成年小鼠组织中,间皮素转录本存在于肺、心、脾、肝、肾和睾丸中。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Mesothelin 抗体 (G-1) 参考文献:

  1. 用于诊断恶性胸膜间皮瘤的血清间皮素:个体患者数据荟萃分析。  |  Hollevoet, K., et al. 2012. J Clin Oncol. 30: 1541-9. PMID: 22412141
  2. 阿马妥昔单抗和针对间皮素的新型药物治疗实体瘤。  |  Baldo, P. and Cecco, S. 2017. Onco Targets Ther. 10: 5337-5353. PMID: 29184420
  3. 间皮素对卵巢癌肿瘤微环境的影响  |  Hilliard, TS. 2018. Cancers (Basel). 10: PMID: 30134520
  4. 作为宫颈癌治疗靶点的间皮素。  |  Jöhrens, K., et al. 2019. Arch Gynecol Obstet. 299: 211-216. PMID: 30324544
  5. 门静脉成纤维细胞中间皮素信号在胆汁淤积性肝纤维化发病机制中的作用。  |  Fuji, H., et al. 2021. Front Mol Biosci. 8: 790032. PMID: 34966784
  6. 间皮素表达在浆液性卵巢癌中的作用:对诊断、预后和治疗目标的影响  |  Giordano, G., et al. 2022. Cancers (Basel). 14: PMID: 35565412
  7. 抗间皮素免疫毒素可诱导间皮瘤根除、抗肿瘤免疫和三级淋巴结构的发育。  |  Liu, W., et al. 2022. Proc Natl Acad Sci U S A. 119: e2214928119. PMID: 36409889
  8. 间皮素表达重塑了免疫基质肿瘤微环境,可预测恶性胸膜间皮瘤患者的死亡风险。  |  Qualiotto, AN., et al. 2023. Front Immunol. 14: 1268927. PMID: 37901248
  9. 用于癌症治疗的新型抗外皮生长因子纳米抗体和具有假单胞菌毒素催化域的重组免疫毒素。  |  Nguyen, MQ., et al. 2023. Mol Cells. 46: 764-777. PMID: 38052492
  10. 突破传统间皮素靶向 CAR-T 细胞疗法治疗恶性间皮瘤的治疗荒漠:未来一瞥。  |  Wang, Y., et al. 2024. Pharmacol Res. 204: 107220. PMID: 38768670

订购信息

产品名称产品编号规格价格数量收藏夹

Mesothelin 抗体 (G-1)

sc-271540
200 µg/ml
RMB2377.00

Mesothelin (G-1): m-IgG Fc BP-HRP 套装

sc-527253
200 µg Ab; 10 µg BP
RMB2662.00

Mesothelin (G-1): m-IgG1 BP-HRP 套装

sc-532626
200 µg Ab; 20 µg BP
RMB2662.00

Mesothelin 抗体 (G-1) AC

sc-271540 AC
500 µg/ml, 25% agarose
RMB3129.00

Mesothelin 抗体 (G-1) HRP

sc-271540 HRP
200 µg/ml
RMB2377.00

Mesothelin 抗体 (G-1) FITC

sc-271540 FITC
200 µg/ml
RMB2482.00

Mesothelin 抗体 (G-1) PE

sc-271540 PE
200 µg/ml
RMB2580.00

Mesothelin 抗体 (G-1) Alexa Fluor® 488

sc-271540 AF488
200 µg/ml
RMB2685.00

Mesothelin 抗体 (G-1) Alexa Fluor® 546

sc-271540 AF546
200 µg/ml
RMB2685.00

Mesothelin 抗体 (G-1) Alexa Fluor® 594

sc-271540 AF594
200 µg/ml
RMB2685.00

Mesothelin 抗体 (G-1) Alexa Fluor® 647

sc-271540 AF647
200 µg/ml
RMB2685.00

Mesothelin 抗体 (G-1) Alexa Fluor® 680

sc-271540 AF680
200 µg/ml
RMB2685.00

Mesothelin 抗体 (G-1) Alexa Fluor® 790

sc-271540 AF790
200 µg/ml
RMB2685.00

I am using Mesothelin (G-1): sc-271540 monoclonal antibody to stain paraffin embedded tissue. Do you recommend antigen retrieval when using this antibody?

Asked by: Germaine
We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-24
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Rated 1 out of 5 by from not happy with itreceived anti-mesothelin antibody as a sample, tried in IF to visualize human mesothelin in cancer cells that are known for the expression of one, did not observr any staining...
Date published: 2018-04-15
Rated 5 out of 5 by from Excellent immunoperoxidase cytoplasmic stainingExcellent immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human tonsil tissue. -SCBT QC
Date published: 2015-05-17
Rated 5 out of 5 by from Satisfactory Western Blot data of MesothelinSatisfactory Western Blot data of Mesothelin expression in non-transfected and human Mesothelin transfected 293T whole cell lysates. -SCBT QC
Date published: 2013-10-29
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Mesothelin 抗体 (G-1) is rated 3.7 out of 5 by 3.
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