Date published: 2025-9-8

021-6093-6350

SCBT Portrait Logo
Seach Input

Mesothelin 抗体 (C-3): sc-166124

5.0(2)
寫評論提問

说明书
  • Mesothelin抗体(C-3)是小鼠单克隆IgG2b κ, 在1篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列291-575位于mouse物种的Mesothelin的C-terminus附近
  • 抗-Mesothelin 抗体 (C-3) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 Mesothelin
  • 抗Mesothelin抗体(C-3)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Mesothelin (C-3): sc-166124免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP2b BP-HRP">m-IgG2b BP-HRPm-IgGκ BP-HRP是Mesothelin Antibody (C-3) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Mesothelin Antibody (C-3) 打包提供(请参阅下面的订购信息)。

快捷链接

関連項目

间皮素抗体(C-3)是一种IgG2bκ型小鼠单克隆间皮素抗体,通过WB、IP、IF和ELISA检测来自小鼠、大鼠和人类的间皮素。间皮素抗体(C-3)既可以是非偶联的抗间皮素抗体形式,也可以是多种偶联形式的抗间皮素抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。间皮素是一种与糖磷脂酰肌醇相连的细胞表面分子,在体腔的间皮细胞层和许多肿瘤细胞中表达。间皮素是人体卵巢癌和间皮瘤表面的肿瘤抗原。间皮素的免疫反应性在卵巢癌(浆液性乳头状、子宫内膜样和未分化)和胰腺癌中较高,而在子宫内膜腺癌、肺癌和胃/食管癌中较少见。在成年小鼠组织中,间皮素转录本存在于肺、心、脾、肝、肾和睾丸中。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Mesothelin 抗体 (C-3) 参考文献:

  1. 间皮素靶向癌症免疫疗法。  |  Hassan, R. and Ho, M. 2008. Eur J Cancer. 44: 46-53. PMID: 17945478
  2. Mesothelin 和 osteopontin。  |  Pantazopoulos, I., et al. 2013. Eur Respir J. 42: 557-8. PMID: 23904556
  3. 发现间皮素并将其作为免疫疗法的靶点。  |  Pastan, I. and Hassan, R. 2014. Cancer Res. 74: 2907-12. PMID: 24824231
  4. 作为靶向治疗生物标志物的间皮素。  |  Lv, J. and Li, P. 2019. Biomark Res. 7: 18. PMID: 31463062
  5. 用于实体瘤的间皮素靶向重组免疫毒素。  |  Hagerty, BL., et al. 2020. Biomolecules. 10: PMID: 32605175
  6. 一种针对间皮素的三特异性杀伤因子能将 NK 细胞靶向肺癌。  |  Kennedy, PR., et al. 2023. Front Immunol. 14: 1060905. PMID: 36911670
  7. 中皮素的生物学和临床意义:现有文献综述。  |  Hagerty, BL. and Takabe, K. 2023. World J Oncol. 14: 340-349. PMID: 37869242
  8. 通过靶向并膜表位,克服了因与脱落的间皮素结合而导致的肿瘤对抗间皮素CAR-T细胞的耐药性。  |  Liu, XF., et al. 2024. Proc Natl Acad Sci U S A. 121: e2317283121. PMID: 38227666
  9. Mesothelin 通过激活 MET 促进非小细胞肺癌的脑转移。  |  Xia, S., et al. 2024. J Exp Clin Cancer Res. 43: 103. PMID: 38570866
  10. 表达肿瘤靶向免疫细胞因子IL-12的间皮素CAR-T细胞可产生持久疗效和较少副作用。  |  Zhu, Y., et al. 2024. Pharmacol Res. 203: 107186. PMID: 38641176

订购信息

产品名称产品编号规格价格数量收藏夹

Mesothelin 抗体 (C-3)

sc-166124
200 µg/ml
RMB2377.00

Mesothelin (C-3): m-IgG Fc BP-HRP 套装

sc-528912
200 µg Ab; 10 µg BP
RMB2662.00

Mesothelin (C-3): m-IgGκ BP-HRP 套装

sc-521517
200 µg Ab, 40 µg BP
RMB2662.00

Mesothelin (C-3): m-IgG2b BP-HRP 套装

sc-550071
200 µg Ab; 10 µg BP
RMB2662.00

Mesothelin 抗体 (C-3) AC

sc-166124 AC
500 µg/ml, 25% agarose
RMB3129.00

Mesothelin 抗体 (C-3) HRP

sc-166124 HRP
200 µg/ml
RMB2377.00

Mesothelin 抗体 (C-3) FITC

sc-166124 FITC
200 µg/ml
RMB2482.00

Mesothelin 抗体 (C-3) PE

sc-166124 PE
200 µg/ml
RMB2580.00

Mesothelin 抗体 (C-3) Alexa Fluor® 488

sc-166124 AF488
200 µg/ml
RMB2685.00

Mesothelin 抗体 (C-3) Alexa Fluor® 546

sc-166124 AF546
200 µg/ml
RMB2685.00

Mesothelin 抗体 (C-3) Alexa Fluor® 594

sc-166124 AF594
200 µg/ml
RMB2685.00

Mesothelin 抗体 (C-3) Alexa Fluor® 647

sc-166124 AF647
200 µg/ml
RMB2685.00

Mesothelin 抗体 (C-3) Alexa Fluor® 680

sc-166124 AF680
200 µg/ml
RMB2685.00

Mesothelin 抗体 (C-3) Alexa Fluor® 790

sc-166124 AF790
200 µg/ml
RMB2685.00

The Antibody (sc-166124) is supplied at 200 µg/mL. How much volume is supplied?

Asked by: Adrie
Thank you for your inquiry. The volume is 1ml. Each vial contains 200 µg IgG2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin. For more questions, please call us toll-free at (800) 457-3801 option 2, e-mail <[email protected]>, or use the live chat on our website.
Answered by: Technical Support 15
Date published: 2017-12-15

I need to use an antibody to detect the protein in samples of bovine origin. Do you know if sc-166124: Mesothelin (C-3) mouse monoclonal antibody will work?

Asked by: Trav11
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support
Date published: 2017-03-06
  • y_2025, m_9, d_6, h_5CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_166124, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 116ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Great for Western blotSpecific and strong, this antibody is a great choice if you need a monoclonal antibody against Mesothelin.
Date published: 2017-02-02
Rated 5 out of 5 by from Good Western blot data of Mesothelin expressionGood Western blot data of Mesothelin expression in non-transfected and mouse Mesothelin transfected 293T whole cell lysates. -SCBT QC
Date published: 2014-07-26
  • y_2025, m_9, d_6, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_2
  • loc_zh_CN, sid_166124, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 17ms
  • REVIEWS, PRODUCT
Mesothelin 抗体 (C-3) is rated 5.0 out of 5 by 2.
  • y_2025, m_9, d_6, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_2
  • loc_zh_CN, sid_166124, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 119ms
  • REVIEWS, PRODUCT