Date published: 2025-9-8

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Mesothelin 抗体 (B-3): sc-166203

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说明书
  • Mesothelin抗体(B-3)是小鼠单克隆IgG1 κ, 在2篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列291-575位于mouse物种的Mesothelin的C-terminus附近
  • 推荐用于 mouse 来源的Mesothelin WB, IP, IF 和 ELISA检测
  • 看 Mesothelin (K1): sc-33672,可查看有标记的 Mesothelin 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是Mesothelin Antibody (B-3) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Mesothelin Antibody (B-3) 打包提供(请参阅下面的订购信息)。

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関連項目

间皮素是一种与糖磷脂酰肌醇相连的细胞表面分子,在体腔的间皮细胞层和许多肿瘤细胞中表达。间皮素是人体卵巢癌和间皮瘤表面的肿瘤抗原。间皮素的免疫反应性在卵巢癌(浆液性乳头状、子宫内膜样和未分化)和胰腺癌中较高,而在子宫内膜腺癌、肺癌和胃/食管癌中较少见。在成年小鼠组织中,间皮素转录本存在于肺、心、脾、肝、肾和睾丸中。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Mesothelin 抗体 (B-3) 参考文献:

  1. 正在进行临床试验和临床前开发的间皮素靶向药物。  |  Kelly, RJ., et al. 2012. Mol Cancer Ther. 11: 517-25. PMID: 22351743
  2. 间皮素在肿瘤进展和靶向治疗中的作用。  |  Tang, Z., et al. 2013. Anticancer Agents Med Chem. 13: 276-80. PMID: 22721387
  3. 作为卵巢癌生物标志物的间皮素:一项荟萃分析。  |  Madeira, K., et al. 2016. An Acad Bras Cienc. 88: 923-32. PMID: 27254448
  4. 新型间皮素抗体-药物共轭物:治疗卵巢癌的现有证据和未来作用。  |  Mauricio, D., et al. 2021. Expert Opin Biol Ther. 21: 1087-1096. PMID: 33356644
  5. 癌症抗原 Mesothelin 及其与治疗性抗体复合物的结构。  |  Zhan, J., et al. 2023. Cancer Res Commun. 3: 175-191. PMID: 36968141
  6. 基于纳米抗体的间皮素表达恶性肿瘤快速成像与阻断治疗抗体兼容。  |  Benloucif, A., et al. 2023. Front Immunol. 14: 1200652. PMID: 37388728
  7. 间皮素靶向 CAR-T 疗法联合伊立替康治疗实体癌。  |  Zhu, Y., et al. 2023. J Cancer Res Clin Oncol. 149: 15027-15038. PMID: 37612388
  8. 间皮素抗原密度影响抗间皮素嵌合抗原受体T细胞的细胞毒性。  |  Chu, GJ., et al. 2024. Cytotherapy. 26: 325-333. PMID: 38349311
  9. 受肿瘤间皮素影响的巨噬细胞会削弱宿主对胰腺癌转移的防御能力  |  Alewine, C. 2024. Cancer Res. 84: 513-514. PMID: 38356442
  10. 间皮素和核苷酸特异性 T 细胞联合短肽可有效杀死三阴性乳腺癌细胞。  |  Thongchot, S., et al. 2024. BMC Med. 22: 400. PMID: 39294656

订购信息

产品名称产品编号规格价格数量收藏夹

Mesothelin 抗体 (B-3)

sc-166203
200 µg/ml
RMB2377.00

Mesothelin (B-3): m-IgG Fc BP-HRP 套装

sc-537456
200 µg Ab; 10 µg BP
RMB2662.00

Mesothelin (B-3): m-IgGκ BP-HRP 套装

sc-534728
200 µg Ab; 40 µg BP
RMB2662.00

Mesothelin (B-3): m-IgG1 BP-HRP 套装

sc-545192
200 µg Ab; 20 µg BP
RMB2662.00

What is the recommended starting dilution for Western blot for sc-166203: Mesothelin (B-3) monoclonal antibody?

Asked by: AbPolly
The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, is available in the recommended protocol: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
Answered by: Technical Support
Date published: 2017-03-22
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Rated 5 out of 5 by from Produced positive Western blot data of MesothelinProduced positive Western blot data of Mesothelin expression in non-transfected and mouse Mesothelin transfected 293T whole cell lysates. -SCBT QC
Date published: 2013-07-27
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Mesothelin 抗体 (B-3) is rated 5.0 out of 5 by 1.
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