Date published: 2025-9-7

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MCT11 抗体 (G-4): sc-515145

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说明书
  • MCT11 抗体 G-4 是小鼠单克隆 IgG2a (kappa轻链),MCT11抗体,规格为200 µg/ml
  • 免疫原氨基酸序列263-309位于human物种的MCT11的内部区域内
  • MCT11 抗体 (G-4) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 MCT11
  • 抗MCT11抗体(G-4)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取MCT11 (G-4): sc-515145免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP2a BP-HRP">m-IgG2a BP-HRPm-IgGκ BP-HRP是MCT11 Antibody (G-4) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与MCT11 Antibody (G-4) 打包提供(请参阅下面的订购信息)。

    快捷链接

    関連項目

    MCT11抗体(G-4)是一种小鼠单克隆IgG2a kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和酶联免疫吸附测定(ELISA)检测小鼠、大鼠和人源的MCT11蛋白。MCT11 (G-4) 抗体有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶 (HRP)、藻红蛋白 (PE)、异硫氰酸荧光素 (FITC) 和多种 Alexa Fluor® 结合物。MCT11,也称为SLC16A11,是单羧酸转运体家族的一员,通过促进乳酸和丙酮酸等单羧酸穿过质膜的转运,在细胞代谢中发挥着至关重要的作用。这种转运对于维持细胞能量水平至关重要,尤其是在无氧呼吸过程中,乳酸作为糖酵解的副产物而积累。MCT11的特征在于其10-12个跨膜螺旋结构域,氨基和羧基末端都位于细胞质中,这使得MCT11能够有效地发挥质子连接转运蛋白的功能。通过调节细胞内的乳酸水平,MCT11有助于防止细胞内pH值下降,从而确保糖酵解能够有效地继续进行,这对于ATP的产生和整体细胞功能至关重要。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    MCT11 抗体 (G-4) 参考文献:

    1. 骨骼肌中的乳酸盐转运--单羧酸盐转运体的作用和调节。  |  Juel, C. and Halestrap, AP. 1999. J Physiol. 517 (Pt 3): 633-42. PMID: 10358105
    2. 质子连接单羧酸盐转运体(MCT)家族:结构, 功能和调节。  |  Halestrap, AP. and Price, NT. 1999. Biochem J. 343 Pt 2: 281-99. PMID: 10510291
    3. SLC16 基因家族--从单羧酸盐转运体(MCT)到芳香性氨基酸转运体及其他。  |  Halestrap, AP. and Meredith, D. 2004. Pflugers Arch. 447: 619-28. PMID: 12739169
    4. 单羧酸盐转运体的分子特征, 调节和功能:对药物输送的影响。  |  Enerson, BE. and Drewes, LR. 2003. J Pharm Sci. 92: 1531-44. PMID: 12884241
    5. 中枢神经系统中的单羧酸盐转运体:分布, 调节和功能。  |  Pierre, K. and Pellerin, L. 2005. J Neurochem. 94: 1-14. PMID: 15953344
    6. 单羧酸盐转运体介导的γ-羟丁酸在人肠 Caco-2 细胞中的转运。  |  Lam, WK., et al. 2010. Drug Metab Dispos. 38: 441-7. PMID: 19952290
    7. 小鼠胎盘中单羧酸盐转运体(MCT)家族的细胞表达。  |  Nagai, A., et al. 2010. Placenta. 31: 126-33. PMID: 20022372

    订购信息

    产品名称产品编号规格价格数量收藏夹

    MCT11 抗体 (G-4)

    sc-515145
    200 µg/ml
    RMB2377.00

    MCT11 (G-4): m-IgG Fc BP-HRP 套装

    sc-531298
    200 µg Ab; 10 µg BP
    RMB2662.00

    MCT11 (G-4): m-IgGκ BP-HRP 套装

    sc-524953
    200 µg Ab, 40 µg BP
    RMB2662.00

    MCT11 (G-4): m-IgG2a BP-HRP 套装

    sc-547755
    200 µg Ab; 10 µg BP
    RMB2662.00

    MCT11 抗体 (G-4) AC

    sc-515145 AC
    500 µg/ml, 25% agarose
    RMB3129.00

    MCT11 抗体 (G-4) HRP

    sc-515145 HRP
    200 µg/ml
    RMB2377.00

    MCT11 抗体 (G-4) FITC

    sc-515145 FITC
    200 µg/ml
    RMB2482.00

    MCT11 抗体 (G-4) PE

    sc-515145 PE
    200 µg/ml
    RMB2580.00

    MCT11 抗体 (G-4) Alexa Fluor® 488

    sc-515145 AF488
    200 µg/ml
    RMB2685.00

    MCT11 抗体 (G-4) Alexa Fluor® 546

    sc-515145 AF546
    200 µg/ml
    RMB2685.00

    MCT11 抗体 (G-4) Alexa Fluor® 594

    sc-515145 AF594
    200 µg/ml
    RMB2685.00

    MCT11 抗体 (G-4) Alexa Fluor® 647

    sc-515145 AF647
    200 µg/ml
    RMB2685.00

    MCT11 抗体 (G-4) Alexa Fluor® 680

    sc-515145 AF680
    200 µg/ml
    RMB2685.00

    MCT11 抗体 (G-4) Alexa Fluor® 790

    sc-515145 AF790
    200 µg/ml
    RMB2685.00

    Why don't you have an over expression control on 293 cells or another cell line?

    Asked by: ACMG
    Thank you for your question. We currently have Western blot data showing endogenous expression of MCT11 in human and rat live tissue extracts. We are always updating our website with new data, check back for updates!
    Answered by: Technical Support
    Date published: 2019-01-26

    What is the recommended starting dilution for Western blot for sc-515145: MCT11 (G-4) monoclonal antibody?

    Asked by: DefinitelyNotMatt
    The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, is available in the recommended protocol: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
    Answered by: Technical Support
    Date published: 2017-03-22
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    Rated 5 out of 5 by from Great antibody for Western Blot of MCT11This antibody works consistently in human liver tissue extract. Shown with Cruz Marker molecular weight standards, sc-2035. -SCBT QC
    Date published: 2023-09-14
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    MCT11 抗体 (G-4) is rated 5.0 out of 5 by 1.
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