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MCP-1 抗体 (5): sc-130328

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说明书
  • MCP-1抗体(5)是小鼠单克隆IgG1 κ, 在3篇文献中引用,规格为200 µg/ml
  • 免疫human物种的重组MCP-1
  • 推荐用于 human 来源的MCP-1 WB, IP 和 ELISA检测
  • 看 MCP-1-4/eotaxin (B-2): sc-377082,可查看有标记的 MCP-1 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP和 m-IgG1 BP-HRP是MCP-1 Antibody (5) for WB applications. 的首选辅助检测试剂,这些试剂现与MCP-1 Antibody (5) 打包提供(请参阅下面的订购信息)。
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嗜酸性粒细胞趋化因子和单核细胞趋化蛋白MCP-1–5构成了C-C(或β)趋化因子的一个亚家族,其特点是一组保守的相邻半胱氨酸。MCPs由多种细胞产生,包括T淋巴细胞,这些细胞随后被IL-1、TNFα和IFN-γ等细胞因子激活。体外研究表明,MCP异构体对不同的淋巴细胞亚群表现出趋化作用。MCP-1是一种有效的嗜碱性粒细胞激活剂,但不影响嗜酸性粒细胞。MCP-1水平在感染和炎症期间会增加,而这两者都以白细胞浸润为特征。已经鉴定出两种在羧基末端有所不同的MCP-1受体。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

MCP-1 抗体 (5) 参考文献:

  1. MCP-1基因激活标志着急性肾损伤。  |  Munshi, R., et al. 2011. J Am Soc Nephrol. 22: 165-75. PMID: 21071523
  2. MCP-1/CCR2B依赖环路上调人气道上皮细胞中的MUC5AC和MUC5B  |  Monzon, ME., et al. 2011. Am J Physiol Lung Cell Mol Physiol. 300: L204-15. PMID: 21097527
  3. MCP-1与氧化低密度脂蛋白结合,由人血浆中的脂蛋白(a)携带。  |  Wiesner, P., et al. 2013. J Lipid Res. 54: 1877-83. PMID: 23667177
  4. MCP-1 在酒精诱导的结直肠癌细胞侵袭性中的作用  |  Xu, M., et al. 2016. Mol Carcinog. 55: 1002-11. PMID: 26014148
  5. MCP-1启动子多态性与脓毒症易感性及进展的相关性研究。  |  He, J., et al. 2017. PLoS One. 12: e0176781. PMID: 28472164
  6. MCP-1基因与SLE之间的关联:荟萃分析。  |  Fang, WL., et al. 2020. J Eur Acad Dermatol Venereol. 34: e198-e200. PMID: 31814187
  7. 姜黄素通过阻断ROCK信号抑制溶血磷脂酸介导的MCP-1表达  |  Zhou, Y., et al. 2021. Molecules. 26: PMID: 33923651
  8. 前脂肪细胞中MCP-1的产生减少是通过PPARγ激活和JNK/SIRT1信号传导介导的。  |  Sawamoto, A., et al. 2024. Biochim Biophys Acta Gen Subj. 1869: 130737. PMID: 39672476
  9. CSF-1、MCP-1/JE和RANTES在成功妊娠期间巨噬细胞募集中的相对作用。  |  Wood, GW., et al. 1997. Mol Reprod Dev. 46: 62-9; discussion 69-70. PMID: 8981365
  10. MCP-1在致死性内毒素血症中保护小鼠。  |  Zisman, DA., et al. 1997. J Clin Invest. 99: 2832-6. PMID: 9185504

订购信息

产品名称产品编号规格价格数量收藏夹

MCP-1 抗体 (5)

sc-130328
200 µg/ml
CNY2422.00

MCP-1 (5): m-IgG Fc BP-HRP 套装

sc-539814
200 µg Ab; 10 µg BP
CNY2715.00

MCP-1 (5): m-IgG1 BP-HRP 套装

sc-541726
200 µg Ab; 20 µg BP
CNY2715.00

I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with MCP-1 (5): sc-130328?

Asked by: cjMara
We recommend using one of our our exclusive Mouse IgG Binding Proteins conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support
Date published: 2017-02-27
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Rated 2 out of 5 by JT from Band detected with human recombinant proteinBand detected with human recombinant protein -SCBT QC
Date published: 2015-02-02
Rated 4 out of 5 by Andreas from Using the above mentioned antibody (1:500)Using the above mentioned antibody (1:500), one band was detected for MCP-1 at approximately 12 kDa via Western blot.
Date published: 2014-11-10
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MCP-1 抗体 (5) is rated 3.0 out of 5 by 2.
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