Date published: 2025-9-8

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Mcl-1 抗体 (MCL-401): sc-69839

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说明书
  • Mcl-1 抗体 MCL-401 是小鼠单克隆 IgG1, 在3篇文献中引用,提供 200 µg/ml
  • 针对全长重组蛋白Mcl-1的抗体,来源于human
  • 推荐用于 human 来源的Mcl-1 WB, IP, IF 和 ELISA检测
  • 看 Mcl-1 (22): sc-12756,可查看有标记的 Mcl-1 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前,我们还没有完成Mcl-1 抗体 (MCL-401)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

B细胞慢性淋巴细胞白血病/淋巴瘤2(Bcl-2)能阻止细胞在接受各种刺激后发生死亡,并在生长因子撤除后赋予某些造血细胞系以抗死亡效应。髓系细胞白血病1(Mcl-1)与Bcl-2具有序列同源性,并且与Bcl-2进一步相似,因为它的表达促进了细胞活性。p53和Mcl-1通过介导Bcl-2拮抗剂杀手(Bak)活性对线粒体凋亡产生相反的作用。Mcl-1是早期造血祖细胞稳态所必需的重要且特异的调节因子。糖原合成酶激酶3(GSK3)控制Mcl-1的稳定性,这影响生长因子、PI 3激酶和AKT对细胞凋亡的调控。Mcl-1蛋白缺乏的小鼠显示B淋巴细胞和T淋巴细胞显著减少,这与在IL-7或IL-7R缺乏的小鼠中观察到的效果相似。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

Mcl-1 抗体 (MCL-401)

sc-69839
200 µg/ml
RMB2377.00

What is the recommended starting dilution for Western blot for Mcl-1 (MCL-401): sc-69839 monoclonal antibody?

Asked by: TinTin
Thank you for your question. The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, can be found in the “datasheet” link at the top of the product page, for which I have provided the link: https://datasheets.scbt.com/sc-69839.pdf If you have any further questions or concerns, please contact our Technical Service department by calling 800-457-3801 option 2, emailing [email protected], or using the Live Chat function on our website.
Answered by: Technical Support
Date published: 2017-03-01
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Rated 4 out of 5 by from Strong pull down in IP in human OVCARStrong pull down in IP in human OVCAR-3 cells,A2780 cells. -SCBT Publication Review
Date published: 2015-04-14
Rated 4 out of 5 by from Robust signal in WB in human recombinant MclRobust signal in WB in human recombinant Mcl-1. -SCBT QC
Date published: 2015-02-18
Rated 4 out of 5 by from Good specificity in WB in Ramos and KGood specificity in WB in Ramos and K-562 whole cell lysates. -SCBT QC
Date published: 2015-01-19
Rated 4 out of 5 by from Good publishable data in WB in mouse A2780sGood publishable data in WB in mouse A2780s, IGROV1, OAW42, A2780cp, OVCAR-3 ,SKOV3. -SCBT Publication Review
Date published: 2014-10-11
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Mcl-1 抗体 (MCL-401) is rated 4.0 out of 5 by 4.
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