Date published: 2025-9-8

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Mast Cell Tryptase 抗体 (AA1): sc-59587

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说明书
  • Mast Cell Tryptase抗体(AA1)是小鼠单克隆IgG1 κ, 在30篇文献中引用,规格为200 µg/ml
  • 纯化的human肺组织蛋白酶
  • 抗-Mast Cell Tryptase 抗体 (AA1) 推荐用于 WB, IP, IF 和 IHC(P),检测mouse, rat 和human 来源的 Mast Cell Tryptase distributed in skin, synovium, lung and heart; 也和以下物种反应,包括: 和 feline and canine; 不会与 any other cell type产生交联反应
  • 抗Mast Cell Tryptase抗体(AA1)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 另提供生物素偶联抗体,可用于WB、IHC(P)和ELISA实验
  • 关于如何获取Mast Cell Tryptase (AA1): sc-59587免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgG1 BP-HRP 是 Mast Cell Tryptase 抗体 (AA1) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与Mast Cell Tryptase 抗体 (AA1) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

肥大细胞胰蛋白酶抗体(AA1)是一种小鼠单克隆 IgG1 kappa 轻链抗体,可通过免疫印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和免疫组织化学等应用检测小鼠、大鼠和人类样本中的肥大细胞胰蛋白酶。抗乳腺细胞胰蛋白酶抗体(AA1)有非共轭型和多种共轭型,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和多种 Alexa Fluor® 共轭物。肥大细胞来源于造血组织,通过分泌各种物质在介导炎症和免疫反应方面发挥着至关重要的作用。肥大细胞胰蛋白酶是胰蛋白酶家族的成员,该家族由丝氨酸蛋白酶组成,这些酶以肝素稳定的四聚体形式具有酶活性。这些酶主要在肥大细胞中表达,参与多个生理过程,包括生成血管活性肽和降解细胞外基质。人类胰蛋白酶基因位于染色体 16p13.3,包括四个功能基因:α I、β I、β II 和 γ I,其中 β 胰蛋白酶是肥大细胞中最主要的同工酶。了解肥大细胞胰蛋白酶的结构和功能至关重要,因为这种蛋白质不仅有助于调节免疫反应,还在过敏和哮喘等各种病理情况中发挥着重要作用。利用肥大细胞胰蛋白酶(AA1)单克隆抗体,研究人员可以深入了解肥大细胞生物学和相关疾病的潜在机制。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Mast Cell Tryptase 抗体 (AA1) 参考文献:

  1. 肥大细胞胰蛋白酶及其在组织重塑中的作用  |  Cairns, JA. 1998. Clin Exp Allergy. 28: 1460-3. PMID: 10024215
  2. 肥大细胞胰蛋白酶,一种仍然神秘的酶。  |  Fiorucci, L. and Ascoli, F. 2004. Cell Mol Life Sci. 61: 1278-95. PMID: 15170507
  3. 肥大细胞胰蛋白酶的生物学。一种炎症介质  |  Hallgren, J. and Pejler, G. 2006. FEBS J. 273: 1871-95. PMID: 16640553
  4. 作为过敏性炎症靶细胞的肥大细胞色氨酸酶 beta:一个不断演变的故事。  |  Sommerhoff, CP. and Schaschke, N. 2007. Curr Pharm Des. 13: 313-32. PMID: 17313363
  5. 一种依赖丝胶蛋白多糖的分泌颗粒蛋白酶--肥大细胞胰蛋白酶对组蛋白的蛋白水解修饰。  |  Melo, FR., et al. 2014. J Biol Chem. 289: 7682-90. PMID: 24478313
  6. 大量饮酒者血清中肥大细胞胰蛋白酶的浓度会降低。  |  Beceiro, C., et al. 2015. Alcohol Clin Exp Res. 39: 672-8. PMID: 25833028
  7. 肥大细胞和肥大细胞色氨酸酶通过蛋白酶活化受体 2 增强人肺成纤维细胞的迁移能力  |  Bagher, M., et al. 2018. Cell Commun Signal. 16: 59. PMID: 30219079
  8. 小鼠肥大细胞胰蛋白酶 Mcpt6 在黑色素瘤中的保护作用  |  Grujic, M., et al. 2020. Pigment Cell Melanoma Res. 33: 579-590. PMID: 31894627
  9. 卵巢子宫内膜样囊肿形成过程中的肥大细胞胰蛋白酶和羧肽酶 A3  |  Atiakshin, D., et al. 2023. Int J Mol Sci. 24: PMID: 37047472
  10. 皮肤光损伤时肥大细胞胰蛋白酶和免疫球蛋白 E 的表达增加:对致癌的影响。  |  Korhonen, J., et al. 2024. J Dermatolog Treat. 35: 2307488. PMID: 38291602

订购信息

产品名称产品编号规格价格数量收藏夹

Mast Cell Tryptase 抗体 (AA1)

sc-59587
200 µg/ml
RMB2377.00

Mast Cell Tryptase (AA1): m-IgG Fc BP-HRP 套装

sc-526939
200 µg Ab; 10 µg BP
RMB2662.00

Mast Cell Tryptase (AA1): m-IgG1 BP-HRP 套装

sc-532312
200 µg Ab; 20 µg BP
RMB2662.00

Mast Cell Tryptase 抗体 (AA1) AC

sc-59587 AC
500 µg/ml, 25% agarose
RMB3129.00

Mast Cell Tryptase 抗体 (AA1) HRP

sc-59587 HRP
200 µg/ml
RMB2377.00

Mast Cell Tryptase 抗体 (AA1) FITC

sc-59587 FITC
200 µg/ml
RMB2482.00

Mast Cell Tryptase 抗体 (AA1) PE

sc-59587 PE
200 µg/ml
RMB2580.00

Mast Cell Tryptase 抗体 (AA1) Alexa Fluor® 488

sc-59587 AF488
200 µg/ml
RMB2685.00

Mast Cell Tryptase 抗体 (AA1) Alexa Fluor® 546

sc-59587 AF546
200 µg/ml
RMB2685.00

Mast Cell Tryptase 抗体 (AA1) Alexa Fluor® 594

sc-59587 AF594
200 µg/ml
RMB2685.00

Mast Cell Tryptase 抗体 (AA1) Alexa Fluor® 647

sc-59587 AF647
200 µg/ml
RMB2685.00

Mast Cell Tryptase 抗体 (AA1) Alexa Fluor® 680

sc-59587 AF680
200 µg/ml
RMB2685.00

Mast Cell Tryptase 抗体 (AA1) Alexa Fluor® 790

sc-59587 AF790
200 µg/ml
RMB2685.00

Mast Cell Tryptase 抗体 (AA1) B

sc-59587 B
200 µg/ml
RMB2407.00

What is the optimal concentration for flow testing? Cat #:sc-59587; Batch #:H1419

Asked by: Anonymous
Thank you for your question. It would be helpful if you could call 800-457-3801, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Service
Date published: 2022-05-10

Hello, my name is Mariia, I am a PhD student in Dublin City University. I'm planning to do experiments with sensory neurons and immunocells. Is it possible to receive free samples of 3 SKU antibodies for testing it, as it mention on the web site? Thanks,

Asked by: Mariia Belinskaia
Please contact our Technical Service Department for more information on how to receive free 10 ug samples of some of our monoclonal antibodies.
Answered by: Technical Support
Date published: 2019-02-13

Can this antibody be used to detect Mast Cell Typtase in bovine samples?

Asked by: AbPolly
Thank you for your question. Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support 15
Date published: 2017-01-19
  • y_2025, m_9, d_7, h_4CST
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Rated 4 out of 5 by from Work fineUsed in mice colon and ileum section by IHC. Look fine
Date published: 2017-03-14
Rated 5 out of 5 by from Great productVery strong western blot data; also nice IHC staining
Date published: 2017-02-02
Rated 5 out of 5 by from Excellent!This antibody works great in western blot analysis of human recombinant Tryptase.
Date published: 2017-01-11
Rated 3 out of 5 by from Worked well with transfected lysate by WBWorked well with transfected lysate by WB -SCBT QC
Date published: 2015-04-26
Rated 4 out of 5 by from Published immunoperoxidase staining usingPublished immunoperoxidase staining using paraffin embedded murine brain samples. -SCBT Publication Review
Date published: 2015-04-12
Rated 4 out of 5 by from Robust band present in western blot analysisRobust band present in western blot analysis of human recombinant Tryptase.
Date published: 2015-02-21
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Mast Cell Tryptase 抗体 (AA1) is rated 4.2 out of 5 by 6.
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