Date published: 2025-9-7

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LRP1 抗体 (5A6): sc-57351

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说明书
  • LRP1 抗体 5A6 是小鼠单克隆 IgG2bLRP1抗体, 在12篇文献中引用,规格为100 µg/ml
  • 针对全长天然LRP1的抗体,来自human来源
  • 推荐用于 mouse, rat 和 human 来源的85 kDa cleaved fragment of Low Density LRP1 WB (non-reducing), IF, IHC(P) 和 FCM检测
  • 关于如何获取LRP1 (5A6): sc-57351免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgG2b BP-HRP 是 LRP1 抗体 (5A6) 在 IHC(P) 应用中的首选二抗检测试剂。这些试剂现与LRP1 抗体 (5A6) 组合成套装提供。 (请参阅下面的订购信息)。

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LRP1 抗体(5A6)是一种小鼠单克隆 IgG2b 抗体,设计用于检测低密度脂蛋白受体相关蛋白 1(LRP1),也称为 α2-巨球蛋白受体(α2MR)。LRP1 是一种大型、多功能的内细胞受体,其特点是结构复杂,包括富含半胱氨酸的 A 类重复序列、表皮生长因子(EGF)样重复序列、YWTD 重复序列和一个 O 链接糖结构域。这种复杂的结构使 LRP1 能够与各种配体相互作用,促进脂质代谢、蛋白酶清除和细胞信号传导等重要过程。LRP1 的结构完整性对于维持细胞平衡和吸收超过 15 种不同的配体(包括 α2 巨球蛋白和载脂蛋白 E(apolipoprotein E,apoE))至关重要。LRP1 主要在大脑、肝脏和肺部等关键组织的细胞表面表达,突出了其在神经系统健康、代谢调节和呼吸功能方面的重要性。抗 LRP1 抗体 (5A6) 以全长原生人类 LRP1 为靶标,特异性识别小鼠、大鼠和人类等多个物种的 85 kDa 蛋白裂解片段,可用于免疫印迹 (WB)、免疫荧光 (IF)、免疫组织化学 (IHC) 和流式细胞术 (FCM) 等应用。通过对 LRP1 的结构域进行精确分析,LRP1 (5A6) 抗体支持对其在生理过程中的关键作用以及在阿尔茨海默病等病理情况中的参与情况进行深入研究,阿尔茨海默病的 LRP1 基因位于第 12 号染色体上的一个重要位点。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

LRP1 抗体 (5A6)

sc-57351
100 µg/ml
RMB2377.00

LRP1 (5A6): m-IgG Fc BP-HRP 套装

sc-539054
100 µg Ab; 10 µg BP
RMB2662.00

LRP1 (5A6): m-IgG2b BP-HRP 套装

sc-549729
100 µg Ab; 10 µg BP
RMB2662.00

I did IHC on paraffin section of mouse brain and used mouse liver as a positive control a few days ago.I found no signal even on positive control. I did antigen retrival with EDTA and used a dilution of 1:50, incubated in 4 celcieus overnight.

Asked by: eugene02
Thank you for your question. Please reach out to our technical service team so they can offer troubleshooting advice on your experiment.
Answered by: Technical Support Europe
Date published: 2020-10-23

What is the recommended secondary reagent to be used with this mouse monoclonal primary?

Asked by: jerojero
We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support 8
Date published: 2017-01-09
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Rated 4 out of 5 by from Tested on HFFF by FACSThis antibody was tested on HFFF cells by FACS and gave a satisfactory signal at dilution 1:25
Date published: 2018-11-16
Rated 5 out of 5 by from Reliable Antibody, Great for FlowThis antibody is well-cited for a variety of applications including IP, IF, and even Flow Cytometry. Reliable antibody.
Date published: 2017-01-16
Rated 5 out of 5 by from Superb indirect FCM analysis of Hep G2 cellsSuperb indirect FCM analysis of Hep G2 cells stained with LRP1 . -SCBT QC
Date published: 2014-02-15
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LRP1 抗体 (5A6) is rated 4.7 out of 5 by 3.
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