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Liprin α1 抗体 (A-6): sc-398030

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说明书
  • Liprin alpha 1 抗体 A-6 是小鼠单克隆 IgM (kappa轻链),Liprin α1抗体,规格为200 µg/ml
  • 特异性抗原位于human物种的Liprin α1的内部区域内的氨基酸522-541之间
  • 推荐用于 mouse, rat 和 human 来源的Liprin α1 WB, IP, IF, IHC(P) 和 ELISA检测
  • 关于如何获取Liprin α1 (A-6): sc-398030免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前,我们还没有完成Liprin α1 抗体 (A-6)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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    関連項目

    Liprin α1抗体(A-6)是一种IgM κ小鼠单克隆Liprin α1抗体(也称为Liprin α1抗体),可通过WB、IP、IF、IHC(P)和ELISA检测到小鼠、大鼠和人类来源的Liprin α1蛋白。Liprin α1抗体(A-6)为非偶联抗Liprin α1抗体。Liprins与白细胞共同抗原相关(LAR)家族跨膜蛋白酪氨酸磷酸酶成员相互作用,后者与轴突导向和乳腺发育有关。Liprins是多价蛋白质,可形成复杂的结构,并作为LAR磷酸酶募集和锚定的支架。根据序列相似性和结合特性,liprins分为α和β两类。α和β liprins均通过其N端卷曲螺旋区域形成同源二聚体。Liprin α1是一种普遍表达的蛋白,与肿瘤抑制因子ING4相互作用,调节细胞迁移,并可能阻止转移。Liprin α1经小牛肠磷酸酶处理后,LAR与Liprin α1的相互作用可减弱。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    Liprin α1 抗体 (A-6) 参考文献:

    1. 果蝇脂蛋白-α和受体磷酸酶Dlar控制突触的形态发生  |  Kaufmann, N., et al. 2002. Neuron. 34: 27-38. PMID: 11931739
    2. AMPA 受体靶向需要脂蛋白-α和 GIT1 之间的相互作用。  |  Ko, J., et al. 2003. J Neurosci. 23: 1667-77. PMID: 12629171
    3. 由突触前 MALS/脂蛋白-α 蛋白复合物调节的突触传递  |  Olsen, O., et al. 2006. Curr Opin Cell Biol. 18: 223-7. PMID: 16504495
    4. 脂蛋白-α在R7光感受器轴突靶向中具有不依赖于LAR的功能。  |  Hofmeyer, K., et al. 2006. Proc Natl Acad Sci U S A. 103: 11595-600. PMID: 16864797
    5. 果蝇光感受器目标选择需要脂蛋白-α。  |  Choe, KM., et al. 2006. Proc Natl Acad Sci U S A. 103: 11601-6. PMID: 16864799
    6. ING4的新型剪接变体及其在细胞生长和运动调控中可能发挥的作用。  |  Unoki, M., et al. 2006. J Biol Chem. 281: 34677-86. PMID: 16973615
    7. 在确定的秀丽隐杆线虫突触中突触前成分的分层组装。  |  Patel, MR., et al. 2006. Nat Neurosci. 9: 1488-98. PMID: 17115039
    8. 生长阻抑剂 4 通过与新型结合伙伴脂蛋白 alpha1 相互作用,抑制细胞扩散和细胞迁移。  |  Shen, JC., et al. 2007. Cancer Res. 67: 2552-8. PMID: 17363573
    9. Liprins 是 LAR 跨膜蛋白-酪氨酸磷酸酶相互作用蛋白家族。  |  Serra-Pagès, C., et al. 1998. J Biol Chem. 273: 15611-20. PMID: 9624153

    订购信息

    产品名称产品编号规格价格数量收藏夹

    Liprin α1 抗体 (A-6)

    sc-398030
    200 µg/ml
    RMB2377.00

    Liprin α1 (A-6) 中和勝肽

    sc-398030 P
    100 µg/0.5 ml
    RMB511.00

    Is it known whether this antibody would also recognize liprin-alpha 1 of murine origin?

    Asked by: 1235486312
    Thank you for your question. Yes, this antibody is recommended for detection of Liprin α1 of mouse, rat and human origin.
    Answered by: Technical Support
    Date published: 2018-11-21

    What application is the blocking peptide sc-398030 P appropriate for?

    Asked by: DefinitelyNotMatt
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-25
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    Rated 5 out of 5 by from Very good Western blot data of Liprin 1Very good Western blot data of Liprin 1 expression in BT-20, MDA-MB-468, Jurkat, HeLa and MDA-MB-231 whole cell lysates. -SCBT QC
    Date published: 2013-06-21
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    Liprin α1 抗体 (A-6) is rated 5.0 out of 5 by 1.
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