Date published: 2025-9-7

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Lefty 抗体 (D-6): sc-365845

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说明书
  • Lefty 抗体 D-6 是小鼠单克隆 IgG1 κ,Lefty抗体, 在2篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于mouse物种的Lefty的C-terminus的氨基酸327-352之间
  • Lefty 抗体 (D-6) 推荐用于 WB, IP, IF 和 ELISA,检测 Lefty-A and Lefty-B of human origin and precursor and mature Lefty-1 and Lefty-2 of mouse and rat
  • 抗Lefty抗体(D-6)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Lefty (D-6): sc-365845免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP是Lefty Antibody (D-6) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与Lefty Antibody (D-6) 搭配使用(请参阅下面的订购信息)。

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関連項目

Lefty抗体(D-6)是一种IgG1 κ小鼠单克隆Lefty抗体(也称为Lefty抗体),可通过WB、IP、IF和ELISA检测小鼠、大鼠和人类来源的Lefty蛋白。Lefty抗体(D-6)既有非偶联抗Lefty抗体形式,也有多种偶联形式的抗Lefty抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。TGFβ超家族由众多生长和分化因子组成,包括转化生长因子(TGF) 1、2和3;生长/分化因子(GDF) 1-9;Mullerian抑制物质(MIS);骨形态发生蛋白(BMP) 2-8;胶质细胞源性神经营养因子(GDNF);抑制素α, β-A, β-B和β-C;Lefty和Nodal。TGF超家族成员参与胚胎发育和成人组织稳态。Lefty-A和Lefty-B是小鼠Lefty-1和Lefty-2的同源物。Lefty-1作为Lefty-2和Nodal的调节因子,对左右轴的决定是必需的。它是一种在发育中的胚胎左侧表达的分泌蛋白。Lefty-1的表达主要在预期的底板(PFP)中,尽管在侧板中胚层(LPM)中可以看到微弱的表达。它参与建立哺乳动物器官系统的左右不对称性。Lefty-A在子宫内膜出血中起作用。该基因的突变与左右轴畸形有关,特别是在心脏和肺部。某些类型的不孕症与子宫内膜中该基因的表达失调有关。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Lefty 抗体 (D-6) 参考文献:

  1. 转化生长因子-β 家族。  |  Massagué, J. 1990. Annu Rev Cell Biol. 6: 597-641. PMID: 2177343
  2. 多种乙型转化生长因子及其受体。  |  Massagué, J., et al. 1987. J Cell Physiol Suppl. Suppl 5: 43-7. PMID: 2890647
  3. 小鼠胚胎中 TGF β 家族成员 lefty 的左右不对称表达。  |  Meno, C., et al. 1996. Nature. 381: 151-5. PMID: 8610011
  4. 一种新的 TGF-beta 超家族成员对小鼠骨骼肌质量的调节。  |  McPherron, AC., et al. 1997. Nature. 387: 83-90. PMID: 9139826
  5. 检测转化生长因子β超家族的新型人类基因 ebaf 基因表达与子宫内膜出血的缔合作用。  |  Kothapalli, R., et al. 1997. J Clin Invest. 99: 2342-50. PMID: 9153275
  6. 左右决定需要 lefty-1,它是 lefty-2 和 nodal 的调节器。  |  Meno, C., et al. 1998. Cell. 94: 287-97. PMID: 9708731

订购信息

产品名称产品编号规格价格数量收藏夹

Lefty 抗体 (D-6)

sc-365845
200 µg/ml
RMB2377.00

Lefty (D-6): m-IgG Fc BP-HRP 套装

sc-525901
200 µg Ab; 10 µg BP
RMB2662.00

Lefty 抗体 (D-6) AC

sc-365845 AC
500 µg/ml, 25% agarose
RMB3129.00

Lefty 抗体 (D-6) HRP

sc-365845 HRP
200 µg/ml
RMB2377.00

Lefty 抗体 (D-6) FITC

sc-365845 FITC
200 µg/ml
RMB2482.00

Lefty 抗体 (D-6) PE

sc-365845 PE
200 µg/ml
RMB2580.00

Lefty 抗体 (D-6) Alexa Fluor® 488

sc-365845 AF488
200 µg/ml
RMB2685.00

Lefty 抗体 (D-6) Alexa Fluor® 546

sc-365845 AF546
200 µg/ml
RMB2685.00

Lefty 抗体 (D-6) Alexa Fluor® 594

sc-365845 AF594
200 µg/ml
RMB2685.00

Lefty 抗体 (D-6) Alexa Fluor® 647

sc-365845 AF647
200 µg/ml
RMB2685.00

Lefty 抗体 (D-6) Alexa Fluor® 680

sc-365845 AF680
200 µg/ml
RMB2685.00

Lefty 抗体 (D-6) Alexa Fluor® 790

sc-365845 AF790
200 µg/ml
RMB2685.00

Lefty (D-6) 中和勝肽

sc-365845 P
100 µg/0.5 ml
RMB511.00

What application is the blocking peptide sc-365845 P appropriate for?

Asked by: Germaine
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-27
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Rated 4 out of 5 by from Lefty (IF)I tested this antibody in IHC (1:100) and I am very satisfied.
Date published: 2024-01-11
Rated 5 out of 5 by from Great for Western of Lefty in mouse ES cellsGood antibody for detecting Lefty in mouse ES cells. Dilution: 1:1000, perfect outcome!
Date published: 2017-09-08
Rated 5 out of 5 by from Great Western Blot data of Lefty expression in nonGreat Western Blot data of Lefty expression in non-transfected and human Lefty transfected 293T whole cell lysates. -SCBT QC
Date published: 2015-04-02
Rated 5 out of 5 by from Good Western Blot data of Lefty expressionGood Western Blot data of Lefty expression in F9 whole cell lysate. -SCBT QC
Date published: 2013-04-23
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Lefty 抗体 (D-6) is rated 4.8 out of 5 by 4.
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