Date published: 2025-9-8

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Latrophilin-3 抗体 (B-6): sc-393576

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说明书
  • Latrophilin-3 抗体 B-6 是小鼠单克隆 IgG2a κ,Latrophilin-3抗体, 在4篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列547-623位于human物种的Latrophilin-3的内部区域内
  • Latrophilin-3 抗体 (B-6) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 all Latrophilin-3 isoforms; 也和以下物种反应,包括: 和 equine, canine, bovine and porcine
  • 抗Latrophilin-3抗体(B-6)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Latrophilin-3 (B-6): sc-393576免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP2a BP-HRP">m-IgG2a BP-HRPm-IgGκ BP-HRP是Latrophilin-3 Antibody (B-6) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Latrophilin-3 Antibody (B-6) 打包提供(请参阅下面的订购信息)。

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関連項目

Latrophilin-3抗体(B-6)是一种IgG2a κ小鼠单克隆Latrophilin-3抗体(也称为Latrophilin-3抗体),可通过WB, IP, IF 和 ELISA检测来自小鼠、大鼠和人类的Latrophilin-3蛋白。Latrophilin-3抗体(B-6)既有非偶联的抗Latrophilin-3抗体形式,也有多种偶联形式的抗Latrophilin-3抗体,包括琼脂糖、辣根过氧化物酶、藻红蛋白、异硫氰酸荧光素和多种Alexa Fluor®偶联物。Latrophilin家族的G蛋白偶联受体由三个成员组成,即latrophilin-1、2和3,每个成员都显示出独特的组织分布和功能。Latrophilin-1是这个家族中特征最明显的成员,作为α-latrotoxin的受体,α-latrotoxin是黑寡妇蜘蛛毒液的一种成分。α-latrotoxin与latrophilin-1的结合通过依赖和不依赖钙离子的机制触发突触囊泡的胞吐作用,导致囊泡耗竭。Latrophilin-1在大脑中含量丰富,并存在于内分泌细胞中。Latrophilin-3也具有脑组织特异性,而latrophilin-2的表达则无处不在。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Latrophilin-3 抗体 (B-6) 参考文献:

  1. latrophilin家族:具有不同组织分布的多重剪接G蛋白偶联受体。  |  Matsushita, H., et al. 1999. FEBS Lett. 443: 348-52. PMID: 10025961
  2. α-拉特罗毒素及其受体 CIRL(拉特罗蛋白)和神经毒素 1 alpha 通过多种机制介导对分泌的影响。  |  Bittner, MA. 2000. Biochimie. 82: 447-52. PMID: 10865131
  3. alpha-latrotoxin 通过与 latrophilin 或 neurexin 相互作用形成钙渗透膜孔。  |  Van Renterghem, C., et al. 2000. Eur J Neurosci. 12: 3953-62. PMID: 11069591
  4. α-Latrotoxin 及其受体:神经毒素和 CIRL/latrophilins。  |  Südhof, TC. 2001. Annu Rev Neurosci. 24: 933-62. PMID: 11520923
  5. 亚太地区具有重要医疗价值的蜘蛛:梭毒素, 拉特罗毒素和相关的蜘蛛神经毒素。  |  Nicholson, GM. and Graudins, A. 2002. Clin Exp Pharmacol Physiol. 29: 785-94. PMID: 12165044
  6. 黑寡妇蜘蛛毒素的多重作用及其在神经分泌研究中的选择性应用。  |  Ushkaryov, YA., et al. 2004. Toxicon. 43: 527-42. PMID: 15066411
  7. Latrophilin GPCRs通过FLRT和teneurins的共价结合来指导突触的特异性。  |  Sando, R., et al. 2019. Science. 363: PMID: 30792275
  8. Latrophilin-2和latrophilin-3在小脑平行纤维突触功能中是必不可少的。  |  Zhang, RS., et al. 2020. Elife. 9: PMID: 32202499
  9. Latrophilin-3的破坏:对大脑和行为的影响。  |  Regan, SL., et al. 2021. Neurosci Biobehav Rev. 127: 619-629. PMID: 34022279
  10. latrophilin-3的替代性剪接控制突触的形成。  |  Wang, S., et al. 2024. Nature. 626: 128-135. PMID: 38233523

订购信息

产品名称产品编号规格价格数量收藏夹

Latrophilin-3 抗体 (B-6)

sc-393576
200 µg/ml
RMB2377.00

Latrophilin-3 (B-6): m-IgG Fc BP-HRP 套装

sc-530505
200 µg Ab; 10 µg BP
RMB2662.00

Latrophilin-3 (B-6): m-IgGκ BP-HRP 套装

sc-524007
200 µg Ab, 40 µg BP
RMB2662.00

Latrophilin-3 (B-6): m-IgG2a BP-HRP 套装

sc-547513
200 µg Ab; 10 µg BP
RMB2662.00

Latrophilin-3 抗体 (B-6) AC

sc-393576 AC
500 µg/ml, 25% agarose
RMB3129.00

Latrophilin-3 抗体 (B-6) HRP

sc-393576 HRP
200 µg/ml
RMB2377.00

Latrophilin-3 抗体 (B-6) FITC

sc-393576 FITC
200 µg/ml
RMB2482.00

Latrophilin-3 抗体 (B-6) PE

sc-393576 PE
200 µg/ml
RMB2580.00

Latrophilin-3 抗体 (B-6) Alexa Fluor® 488

sc-393576 AF488
200 µg/ml
RMB2685.00

Latrophilin-3 抗体 (B-6) Alexa Fluor® 546

sc-393576 AF546
200 µg/ml
RMB2685.00

Latrophilin-3 抗体 (B-6) Alexa Fluor® 594

sc-393576 AF594
200 µg/ml
RMB2685.00

Latrophilin-3 抗体 (B-6) Alexa Fluor® 647

sc-393576 AF647
200 µg/ml
RMB2685.00

Latrophilin-3 抗体 (B-6) Alexa Fluor® 680

sc-393576 AF680
200 µg/ml
RMB2685.00

Latrophilin-3 抗体 (B-6) Alexa Fluor® 790

sc-393576 AF790
200 µg/ml
RMB2685.00

What is the epitope for this antibody?

Asked by: NAPH
Thank you for your question. Anti-Latrophilin-3 Antibody (B-6): sc-393576 was raised against amino acids 547-623 mapping within an internal region of Latrophilin-3 of human origin.
Answered by: Tech Support Europe
Date published: 2022-02-17

For Western Blot, is it recommended to use denatured or non-denatured conditions with Latrophilin-3 (B-6): sc-393576 monoclonal antibody?

Asked by: jenniferc
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Answered by: Technical Support
Date published: 2017-02-27
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Rated 5 out of 5 by from Strong antibodyWorks very well for WB in human neural stem cells. Sharp band observed when freshly diltued.
Date published: 2017-12-14
Rated 5 out of 5 by from Great Western Blot data of LatrophilinGreat Western Blot data of Latrophilin-3 expression in Hep G2 whole cell lysate. -SCBT QC
Date published: 2015-03-22
Rated 5 out of 5 by from Produced positive Western Blot data of LatrophilinProduced positive Western Blot data of Latrophilin-3 expression in COLO 320DM whole cell lysate. -SCBT QC
Date published: 2014-10-30
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Latrophilin-3 抗体 (B-6) is rated 5.0 out of 5 by 3.
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