Date published: 2025-9-8
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LASS6 Antibody (L-18) - Western Blotting - Image 368265
LASS6 抗体 (L-18): sc-100554. Jurkat (A), IMR-32 (B), Hep G2 (C), NIH/3T3 (D) 和 NRK (E) 全细胞裂解液及小鼠肾组织提取物 (F) 中 LASS6 表达的 Western 印迹分析.
LASS6 抗体 (L-18): sc-100554. Jurkat (A), IMR-32 (B), Hep G2 (C), NIH/3T3 (D) 和 NRK (E) 全细胞裂解液及小鼠肾组织提取物 (F) 中 LASS6 表达的 Western 印迹分析.

LASS6 抗体 (L-18): sc-100554

5.0(6)
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说明书
  • LASS6 抗体 L-18 是小鼠单克隆 IgG2a κ，LASS6抗体, 在11篇文献中引用，规格为100 µg/ml
  • 免疫human物种的重组LASS6
  • 推荐用于 mouse, rat 和 human 来源的LASS6 WB, IP, IF, IHC(P) 和 ELISA检测
  • 关于如何获取LASS6 (L-18): sc-100554的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP 和 m-IgG2a BP-HRP 是 LASS6 抗体 (L-18) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与LASS6 抗体 (L-18) 组合成套装提供。 (请参阅下面的订购信息)。

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描述
基因信息
说明书与实验方案
研究信息

関連項目

此外 LASS 抗体 包括 LASS1, LASS2, LASS4和LASS6

LASS6抗体（L-18）是一种IgG2a κ小鼠单克隆LASS6抗体（也称为LASS6抗体），可通过WB、IP、IF、IHC(P)和ELISA检测到小鼠、大鼠和人类来源的LASS6蛋白。LASS6抗体（L-18）为非偶联形式的抗LASS6抗体。从酵母到哺乳动物，LASS（长寿保证同源物）家族成员都高度保守。该蛋白质家族已有六个成员被鉴定出来（LASS1、LASS2、LASS3、LASS4、LASS5和LASS6），它们都参与鞘脂的合成。LASS6是一种广泛表达的384个氨基酸内质网多通道膜蛋白。在内质网膜的腔侧，N端的天冬酰胺残基被糖基化。在CLN9缺陷的细胞中，LASS6可以纠正生长和凋亡，并增加短神经酰胺种类（如C14:0-和C16:0-神经酰胺）的水平。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

LASS6 抗体 (L-18) 参考文献:

  1. 哺乳动物 Lass6 及其相关家族成员调控特定神经酰胺的合成。  |  Mizutani, Y., et al. 2005. Biochem J. 390: 263-71. PMID: 15823095
  2. LASS6，长寿保证基因家族的另一个成员。  |  Weinmann, A., et al. 2005. Int J Mol Med. 16: 905-10. PMID: 16211262
  3. 二氢甘油酰胺合成酶的调节因子 CLN9 蛋白。  |  Schulz, A., et al. 2006. J Biol Chem. 281: 2784-94. PMID: 16303764
  4. LASS3（长寿保证同源物 3）主要是一种睾丸特异性（二氢）神经酰胺合成酶，具有相对广泛的底物特异性。  |  Mizutani, Y., et al. 2006. Biochem J. 398: 531-8. PMID: 16753040

订购信息

产品名称产品编号规格价格数量收藏夹

LASS6 抗体 (L-18)

sc-100554
100 µg/ml
RMB2504.00

LASS6 (L-18): m-IgG Fc BP-HRP 套装

sc-539697
100 µg Ab; 10 µg BP
RMB2662.00

LASS6 (L-18): m-IgG2a BP-HRP 套装

sc-546759
100 µg Ab; 10 µg BP
RMB2662.00

To which part of the protein does the enzyme attach? I am doing many mutations and chimeras and I need to know if this could detect them.

Asked by: Idzr
Thank you for your question. It would be helpful if you could call us directly at 800-457-3801ext.1, allowing for a more interactive discussion of this and other related questions.
Answered by: Blake J
Date published: 2021-11-23

Can sc-100554: LASS6 (L-18) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: Randy McDonald
Thank you for your question. Yes, sc-100554: LASS6 (L-18) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-03-24
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Rated 5 out of 5 by from Great antibodyWe used this antibody in 1:300 diluition at room temperature for 2 hours and it performed very well. Cell extracts tested with this antibody originates fron primary effusion lymphoma cell line BC3
Date published: 2024-11-14
Rated 5 out of 5 by from Great Western BlotWestern Blot analysis in A549s revealed a clear, strong band for CerS6
Date published: 2018-07-10
Rated 5 out of 5 by from great antibodyI tried this antibody with mouse RAW 264.7 cells, the western blot result shown a clean and strong band.
Date published: 2017-07-20
Rated 5 out of 5 by from Good western blotWe used this antibody for western blot and got a positive band for the correct molecular weight in HeLa cells
Date published: 2017-01-17
Rated 5 out of 5 by from Produced exceptional immunoperoxidase membraneProduced exceptional immunoperoxidase membrane and cytoplasmic staining in formalin-fixed, paraffin-embedded human colon tissue. -SCBT QC
Date published: 2015-04-16
Rated 5 out of 5 by from Worked well for western blot analysis ofWorked well for western blot analysis of LASS6 expression in HL-60, MOLT-4, Jurkat, HeLa and COLO 205 whole cell lysates. -SCBT QC
Date published: 2015-04-16
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LASS6 抗体 (L-18) is rated 5.0 out of 5 by 6.
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