Date published: 2025-9-7
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Laminin-R Antibody (MLuC5) - Immunofluorescence - Image 142923
层粘连蛋白-R 抗体 (MLuC5): sc-59732. 甲醇固定的 HeLa 细胞免疫荧光染色, 显示膜定位.
Laminin-R Antibody (MLuC5) - Immunofluorescence - Image 142923
层粘连蛋白-R 抗体 (MLuC5): sc-59732. 甲醇固定的 HeLa 细胞免疫荧光染色, 显示膜定位.
Laminin-R Antibody (MLuC5) - Western Blotting - Image 129503
层粘蛋白-R 抗体 (MLuC5): sc-59732. MCF7 (A) 和 PC-3 (B) 全细胞裂解液中 Laminin-R 表达的 Western 印迹分析.
Laminin-R Antibody (MLuC5) - Western Blotting - Image 33114
层粘蛋白-R 抗体 (MLuC5): sc-59732. 未转染: sc-117752 (A) 和转染: sc-116343 (B) 293T 全细胞裂解液中 Laminin-R 表达的 Western 印迹分析.
层粘连蛋白-R 抗体 (MLuC5): sc-59732. 甲醇固定的 HeLa 细胞免疫荧光染色, 显示膜定位.

Laminin-R 抗体 (MLuC5): sc-59732

4.4(5)
寫評論提問

说明书
  • Laminin-R抗体(MLuC5)是小鼠单克隆IgM κ, 在11篇文献中引用，规格为200 µg/ml
  • 针对human活体N592小细胞肺癌细胞系
  • 推荐用于 mouse, rat 和 human 来源的Laminin-R WB, IP, IF, IHC(P) 和 FCM检测
  • 还可偶联藻红蛋白 以及 FITC 用于IF, IHC(P) 和 FCM
  • 看 Laminin-R (H-2): sc-74515，可查看有标记的 Laminin-R 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前，我们还没有完成Laminin-R 抗体 (MLuC5)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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描述
基因信息
说明书与实验方案
研究信息

関連項目

层粘连蛋白受体（Laminin-R）具有与纤维连接蛋白和玻连蛋白等其他细胞外基质蛋白受体相似的异二聚体结构。层粘连蛋白-R结合到溶酶体膜上，使溶酶体能够附着在涂有层粘连蛋白的表面。这种和其他特性将层粘连蛋白-R鉴定为细胞粘附受体整联蛋白家族的成员。层粘连蛋白R前体是一种多肽，在侵袭性癌中的表达始终上调。前体也被鉴定为p40核糖体相关蛋白，似乎是一种参与翻译机制的多功能蛋白。层粘连蛋白-R（也称为结肠癌层粘连蛋白结合蛋白），在结肠癌中的含量是邻近正常结肠上皮的9倍。此外，肺癌症细胞系中的层粘连蛋白-R水平高于肺细胞系。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Laminin-R 抗体 (MLuC5) 参考文献:

  1. 碳水化合物结合蛋白35是结肠癌中主要的细胞表面层粘连蛋白结合蛋白。  |  Lee, EC., et al. 1991. Arch Surg. 126: 1498-502. PMID: 1842179
  2. dCas9-VP160可增加层粘连蛋白亚基α1链的表达。  |  Perrin, A., et al. 2017. Mol Ther Nucleic Acids. 6: 68-79. PMID: 28325301
  3. 慢性阻塞性肺病中LABA/LAMA联合治疗与LAMA单药治疗或LABA/ICS治疗的比较：系统评价和荟萃分析。  |  Rodrigo, GJ., et al. 2017. Int J Chron Obstruct Pulmon Dis. 12: 907-922. PMID: 28360514
  4. 慢性阻塞性肺病患者使用LABA/LAMA固定剂量组合：系统综述。  |  Rogliani, P., et al. 2018. Int J Chron Obstruct Pulmon Dis. 13: 3115-3130. PMID: 30323582
  5. COPD患者使用单一吸入器LABA/LAMA。  |  Malerba, M., et al. 2019. Front Pharmacol. 10: 390. PMID: 31105560
  6. 在初级保健哮喘管理中，比较LAMA、LABA和LTRA作为附加疗法的疗效。  |  Kaplan, A., et al. 2020. NPJ Prim Care Respir Med. 30: 50. PMID: 33177503
  7. 长效抗胆碱药（LAMA）加长效β-受体激动剂（LABA）对比LABA加吸入性皮质类固醇（ICS）治疗慢性阻塞性肺疾病。  |  Fukuda, N., et al. 2023. Cochrane Database Syst Rev. 6: CD012066. PMID: 37276335
  8. 哮喘的基线特征和ICS/LAMA/LABA反应：CAPTAIN研究分析。  |  Boulet, LP., et al. 2024. J Allergy Clin Immunol Pract. 12: 1244-1253.e8. PMID: 38309696
  9. LAMA比LABA更能改善慢性阻塞性肺病患者的组织氧合。  |  Perez-Bogerd, S., et al. 2024. J Appl Physiol (1985). 137: 154-165. PMID: 38722752
  10. 在现有ICS治疗基础上添加LABA或LAMA治疗不受控制的哮喘。  |  Fletke, KJ. and Trasybule, N. 2024. Am Fam Physician. 110: 346-347. PMID: 39418565

订购信息

产品名称产品编号规格价格数量收藏夹

Laminin-R 抗体 (MLuC5)

sc-59732
200 µg/ml
RMB2377.00

Laminin-R 抗体 (MLuC5) FITC

sc-59732 FITC
200 µg/ml
RMB2482.00

Laminin-R 抗体 (MLuC5) PE

sc-59732 PE
200 µg/ml
RMB2580.00

Hello, Is there azide or other type of preservative mixed with MLuC5 (sc-59732)? Thanks.

Asked by: Rutdol
Thank you for your question. Yes, each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin.
Answered by: Tech Service
Date published: 2020-03-04

Can Laminin-R (MLuC5): sc-59732 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: DefinitelyNotMatt
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, Laminin-R (MLuC5): sc-59732 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from High Quality ProductThe Laminin-R Antibody (MLuC5): sc-59732 works very well for immunofluorescence applications showing staining pattern with membrane localization.
Date published: 2017-02-09
Rated 5 out of 5 by from using antibdoy blockinglaminin r antibody 5μg/ml in macrophage have good result.
Date published: 2016-11-20
Rated 4 out of 5 by from Worked well with transfected lysate by WBWorked well with transfected lysate by WB. -SCBT QC
Date published: 2015-05-14
Rated 4 out of 5 by from Produced robust immunofluorescence membraneProduced robust immunofluorescence membrane staining in methanol-fixed HeLa cells. -SCBT QC
Date published: 2015-04-02
Rated 4 out of 5 by from Bands seen in WB using MCF7 and PCBands seen in WB using MCF7 and PC-3 whole cell lysates. -SCBT QC
Date published: 2015-01-03
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Laminin-R 抗体 (MLuC5) is rated 4.4 out of 5 by 5.
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