Date published: 2025-9-7

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L-type Ca++ CP β1 抗体 (Y-2D68): sc-134377

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  • L-type Ca++ CP beta 1 抗体 Y-2D68 是小鼠单克隆 IgG2a (kappa轻链),L-type Ca++ CP β1抗体,规格为100 µg/ml
  • 针对human重组L-type Ca++ CP β1蛋白的抗原性氨基酸
  • 推荐用于 human 来源的L-type Ca++ CP β1 WB, IP 和 ELISA检测
  • 关于如何获取L-type Ca++ CP β1 (Y-2D68): sc-134377免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前,我们还没有完成L-type Ca++ CP β1 抗体 (Y-2D68)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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    L-型Ca++ CP β1抗体(Y-2D68)是一种IgG2a κ小鼠单克隆L-型Ca++ CP beta 1抗体(也称为L-型Ca++ CP β1抗体),可通过蛋白质印迹、免疫沉淀和酶联免疫吸附试验检测人类来源的L-型Ca++ CP beta 1蛋白。L-型Ca++ CP β1抗体(Y-2D68)以非偶联形式的抗L-型Ca++ CP beta 1抗体形式提供。电压依赖性Ca2+通道在膜去极化时介导Ca2+进入可兴奋细胞,并参与各种Ca2+依赖过程,包括肌肉收缩、激素或神经递质释放以及基因表达。钙通道是由α-1亚基、细胞内β亚基、二硫键连接的α-2/δ亚基和跨膜γ亚基组成的高度多样化的多聚体复合物。根据Ca2+电流的生物物理和药理特性,可将其分为L-、N-、T-、P-、Q-和R-型。L-型Ca2+电流可引发肌肉收缩、内分泌分泌和基因转录,并可通过第二信使激活的蛋白质磷酸化途径进行调节。L-型钙通道可与G蛋白偶联受体形成大分子信号复合物,从而提高调节特定靶标的选择性。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    L-type Ca++ CP β1 抗体 (Y-2D68) 参考文献:

    1. 电压门控 Ca2+ 通道的结构和调节。  |  Catterall, WA. 2000. Annu Rev Cell Dev Biol. 16: 521-55. PMID: 11031246
    2. 与 Ca2+ 通道 Cav1.2 组装在一起的 beta2 肾上腺素能受体信号复合体。  |  Davare, MA., et al. 2001. Science. 293: 98-101. PMID: 11441182
    3. 钙通道的分子生物学。  |  Perez-Reyes, E. and Schneider, T. 1995. Kidney Int. 48: 1111-24. PMID: 8569073
    4. 电压门控 Ca2+ 通道多样性的分子基础:现在是 T 的时候了吗?  |  Randall, AD. 1998. J Membr Biol. 161: 207-13. PMID: 9493126

    订购信息

    产品名称产品编号规格价格数量收藏夹

    L-type Ca++ CP β1 抗体 (Y-2D68)

    sc-134377
    100 µg/ml
    RMB2504.00

    Do you know the amino-acidic sequence corresponding to the epitope recognized by the antibody L-type Ca++ CP β1 (Y-2D68): sc-134377? Is it possible to have a trial sample? Thank you in advance Regards Sestina Falcone

    Asked by: Sesti
    Thank you for your question. This mouse monoclonal antibody, L-type Ca++ CP β1 (Y-2D68): sc-134377, is raised against a recombinant protein with an epitope mapping between amino acids 500-600 of L-type Ca++ CP β1 protein of human origin. The exact epitope recognized by the antibody has not been determined. Unfortunately, we do not offer a sample size of this antibody at this time. If you purchase the antibody, and it does not work for you in any of the recommended applications, we will warranty it and provide you with a free replacement or refund if we can not successfully troubleshoot the antibody.
    Answered by: Technical Support
    Date published: 2017-05-17

    For Western Blot, is it recommended to use denatured or non-denatured conditions with L-type Ca++ CP β1 (Y-2D68): sc-134377 antibody?

    Asked by: jerojero
    Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
    Answered by: Technical Support
    Date published: 2017-03-27
    • y_2025, m_8, d_31, h_8CST
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    Rated 5 out of 5 by from bandas especificasPara ensayos de Western blot se detectan bandas especificas, lamentablemente para ensayos de IP se observan bandas inespecíficas en los carriles de control negativo
    Date published: 2024-12-06
    Rated 5 out of 5 by from Good for Western BlotAntibody detects L-type Ca++ CP β1 in human L-type Ca++ CP β1 transfected cell lysates by Western blot. -SCBT QC
    Date published: 2023-09-14
    Rated 3 out of 5 by from Positive bands of interest observed in WBPositive bands of interest observed in WB in human L-type Ca++ CP 1 transfected 293T whole cell lysate. -SCBT QC
    Date published: 2015-03-22
    Rated 3 out of 5 by from Worked well in WB in human LWorked well in WB in human L-type Ca++ CP 1 transfected 293T whole cell lysate. -SCBT QC
    Date published: 2013-03-05
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    L-type Ca ++ CP β1 抗体 (Y-2D68) is rated 4.0 out of 5 by 4.
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