Date published: 2025-9-8

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L-Selectin/CD62L/SELL 抗体 (DREG56): sc-18851

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说明书
  • L-Selectin/CD62L/SELL抗体(DREG56)是小鼠单克隆IgG1 κ, 在13篇文献中引用,规格为200 µg/ml
  • 针对PHA激活的human外周血白细胞
  • 推荐用于 human 来源的L-Selectin IF 和 FCM检测
  • 可提供偶联藻红蛋白, FITC, Alexa Fluor® 488 或者Alexa Fluor® 647 的产品, 应用于IF, IHC(P)和FCM
  • m-IgGκ BP-HRP是L-Selectin/CD62L/SELL Antibody (DREG56). 的首选辅助检测试剂。该试剂现可与L-Selectin/CD62L/SELL Antibody (DREG56) 搭配使用(请参阅下面的订购信息)。有关其它 m-IgGκ BP 结合物,请参阅我们完整的小鼠 IgG 结合蛋白列表。

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选择素,又称CD62抗原,是一类与糖类结合的蛋白质,参与细胞与白细胞间的相互作用。L-Selectin(又称LECAM-1或CD62L)表达于大多数B细胞和未分化的T细胞以及大多数单核细胞、中性粒细胞和嗜酸性粒细胞上。L-Selectin与激活的内皮细胞表达的特定糖类相互作用。P-Selectin(又称GMP-140或CD62P)表达于激活的血小板和内皮细胞,E-Selectin(又称ELMA-1或CD62E)表达于内皮细胞,它们具有重叠的配体特异性。它们均能识别唾液基肽酸为配体,并结合中性粒细胞和单核细胞上的特定糖类。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

L-Selectin/CD62L/SELL 抗体 (DREG56) 参考文献:

  1. 调节L-选择素依赖性白细胞粘附和迁移的信号。  |  Ivetic, A. 2013. Int J Biochem Cell Biol. 45: 550-5. PMID: 23299028
  2. L-选择素缺乏会减少主动脉B1a和Breg亚群并促进动脉粥样硬化。  |  Gjurich, BN., et al. 2014. Thromb Haemost. 112: 803-11. PMID: 24989887
  3. L-选择素的易超分子适配体抑制剂。  |  Chang, EK., et al. 2015. PLoS One. 10: e0123034. PMID: 25826688
  4. L-选择素通过上调体外TLR4的表达促进树突状细胞成熟。  |  Ye, Z., et al. 2017. Ann Clin Lab Sci. 47: 389-394. PMID: 28801363
  5. 慢性淋巴细胞白血病中L-选择素表达受磷酸酶活性影响。  |  Beke Debreceni, I., et al. 2019. Cytometry B Clin Cytom. 96: 149-157. PMID: 30729673
  6. L-Selectin增强T细胞可提高癌症免疫疗法的有效性。  |  Watson, HA., et al. 2019. Front Immunol. 10: 1321. PMID: 31249570
  7. L-选择素表达与乳腺癌的炎性微环境和良好预后相关。  |  Kumari, S., et al. 2021. 3 Biotech. 11: 38. PMID: 33479593
  8. 对IAV感染的免疫反应以及L-选择素和ADAM17在淋巴细胞归巢中的作用。  |  Reed, SG. and Ager, A. 2022. Pathogens. 11: PMID: 35215094
  9. 在淋巴结中靶向L-选择素淋巴细胞以递送免疫抑制药物,从而实现持久的多发性硬化症治疗。  |  Zhao, Y., et al. 2023. Adv Sci (Weinh). 10: e2300738. PMID: 37170724
  10. 慢性髓细胞白血病中CD34阳性细胞的L-选择素表达。  |  Kimura, A., et al. 1998. Leuk Lymphoma. 28: 399-404. PMID: 9517512

订购信息

产品名称产品编号规格价格数量收藏夹

L-Selectin/CD62L/SELL 抗体 (DREG56)

sc-18851
200 µg/ml
RMB2377.00

L-Selectin/CD62L/SELL (DREG56): m-IgGκ BP-HRP 套装

sc-533754
200 µg Ab; 40 µg BP
RMB2662.00

L-Selectin/CD62L/SELL 抗体 (DREG56) Alexa Fluor® 488

sc-18851 AF488
200 µg/ml
RMB2685.00

L-Selectin/CD62L/SELL 抗体 (DREG56) Alexa Fluor® 647

sc-18851 AF647
200 µg/ml
RMB2685.00

L-Selectin/CD62L/SELL 抗体 (DREG56) FITC

sc-18851 FITC
200 µg/ml
RMB2482.00

L-Selectin/CD62L/SELL 抗体 (DREG56) PE

sc-18851 PE
200 µg/ml
RMB2580.00

How can L-Selectin (DREG56): sc-18851 mouse monoclonal antibody be used for double or triple staining, if the other primary antibodies are also raised in mouse?

Asked by: Professor Griffin
In this case, we recommend using a directly conjugated mouse monoclonal primary antibody. This antibody is available conjugated to phycoerythrin (sc-18851 PE) or fluoroscein (sc-18851 FITC).
Answered by: Technical Support
Date published: 2017-02-27
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Rated 5 out of 5 by from IF publication with paraformaldehyde fixedIF publication with paraformaldehyde fixed human neutrophil samples. -SCBT Publication Review
Date published: 2015-05-04
Rated 5 out of 5 by from Published good quality flow cytometry dataPublished good quality flow cytometry data in human peripheral blood. -SCBT Publication Review
Date published: 2015-03-19
Rated 5 out of 5 by from Fantastic Western blot and IP data gatheredFantastic Western blot and IP data gathered using Jurkat T cells. -SCBT Publication Review
Date published: 2015-03-17
Rated 5 out of 5 by from Great FCM analysis of SUPGreat FCM analysis of SUP-T1 cells. -SCBT QC
Date published: 2013-05-24
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L-Selectin/CD62L/SELL 抗体 (DREG56) is rated 5.0 out of 5 by 4.
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