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L-Selectin/CD62L/SELL 抗体 (DREG55): sc-18905

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说明书
  • L-Selectin/CD62L/SELL抗体(DREG55)是小鼠单克隆IgG1 κ, 在1篇文献中引用,规格为200 µg/ml
  • 针对human外周血白细胞,用PMA诱导
  • 推荐用于 human 来源的L-Selectin IF 和 FCM检测
  • 还可偶联藻红蛋白 以及 FITC 用于IF, IHC(P) 和 FCM
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是L-Selectin/CD62L/SELL Antibody (DREG55). 的首选辅助检测试剂。这些试剂现与L-Selectin/CD62L/SELL Antibody (DREG55) 打包提供(请参阅下面的订购信息)。

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関連項目

选择素,又称CD62抗原,是一类与糖类结合的蛋白质,参与细胞与白细胞间的相互作用。L-Selectin(又称LECAM-1或CD62L)表达于大多数B细胞和未分化的T细胞以及大多数单核细胞、中性粒细胞和嗜酸性粒细胞上。L-Selectin与激活的内皮细胞表达的特定糖类相互作用。P-Selectin(又称GMP-140或CD62P)表达于激活的血小板和内皮细胞,E-Selectin(又称ELMA-1或CD62E)表达于内皮细胞,它们具有重叠的配体特异性。它们均能识别唾液基肽酸为配体,并结合中性粒细胞和单核细胞上的特定糖类。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

L-Selectin/CD62L/SELL 抗体 (DREG55) 参考文献:

  1. L-选择素和E-选择素在过敏性肺炎中的上调。  |  Navarro, C., et al. 2002. Chest. 121: 354-60. PMID: 11834643
  2. L-选择素:趋化因子功能的新兴参与者。  |  Khan, AI. and Kubes, P. 2003. Microcirculation. 10: 351-8. PMID: 12851651
  3. L-选择素与系统性硬化症的皮肤损伤。  |  Dunne, JV., et al. 2012. PLoS One. 7: e44814. PMID: 23028631
  4. 输卵管妊娠中人类输卵管上皮细胞中的L-选择素配体表达。  |  Li, S., et al. 2014. Biol Reprod. 90: 133. PMID: 24829027
  5. L-选择素脱落仅在单核细胞迁移的假足内激活,以调节细胞极性。  |  Rzeniewicz, K., et al. 2015. Proc Natl Acad Sci U S A. 112: E1461-70. PMID: 25775539
  6. HIV-1 以 L 选择素为粘附目标,并诱导其脱落以释放病毒。  |  Kononchik, J., et al. 2018. Nat Commun. 9: 2825. PMID: 30026537
  7. 实时脱落对膜残留L-选择素与PSGL-1结合动力学的影响。  |  Peng, S., et al. 2019. Am J Physiol Cell Physiol. 316: C678-C689. PMID: 30726114
  8. ADAM17依赖性L-选择素的蛋白水解促进细胞毒性T细胞的早期克隆扩增。  |  Mohammed, RN., et al. 2019. Sci Rep. 9: 5487. PMID: 30940840
  9. L-Selectin/CD62L是导致小鼠和人类非酒精性脂肪性肝炎的关键因素。  |  Drescher, HK., et al. 2020. Cells. 9: PMID: 32365632
  10. L-选择素介导的淋巴细胞在MAdCAM-1上的滚动。  |  Berg, EL., et al. 1993. Nature. 366: 695-8. PMID: 7505053

订购信息

产品名称产品编号规格价格数量收藏夹

L-Selectin/CD62L/SELL 抗体 (DREG55)

sc-18905
200 µg/ml
RMB2377.00

L-Selectin/CD62L/SELL (DREG55): m-IgG Fc BP-HRP 套装

sc-536613
200 µg Ab; 10 µg BP
RMB2662.00

L-Selectin/CD62L/SELL (DREG55): m-IgGκ BP-HRP 套装

sc-533769
200 µg Ab; 40 µg BP
RMB2662.00

L-Selectin/CD62L/SELL (DREG55): m-IgG1 BP-HRP 套装

sc-544708
200 µg Ab; 20 µg BP
RMB2662.00

L-Selectin/CD62L/SELL 抗体 (DREG55) FITC

sc-18905 FITC
200 µg/ml
RMB2482.00

L-Selectin/CD62L/SELL 抗体 (DREG55) PE

sc-18905 PE
200 µg/ml
RMB2580.00

How can L-Selectin (DREG55): sc-18905 mouse monoclonal antibody be used for double or triple staining, if the other primary antibodies are also raised in mouse?

Asked by: Randy McDonald
In this case, we recommend using a directly conjugated mouse monoclonal primary antibody. This antibody is available conjugated to phycoerythrin (sc-18905 PE) or fluoroscein (sc-18905 FITC).
Answered by: Technical Support
Date published: 2017-03-01
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Rated 5 out of 5 by from Superb FCM analysis of human peripheral bloodSuperb FCM analysis of human peripheral blood leukocytes. -SCBT QC
Date published: 2013-06-24
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L-Selectin/CD62L/SELL 抗体 (DREG55) is rated 5.0 out of 5 by 1.
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