Date published: 2025-9-8

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Ku86 抗体 (Ku15): sc-33653

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说明书
  • Ku86抗体(Ku15)是小鼠单克隆IgG1 κ, 在1篇文献中引用,规格为200 µg/ml
  • 针对431 human表皮样癌细胞系
  • 推荐用于 human 来源的Ku86 WB, IP, IF 和 IHC(P)检测
  • 看 Ku86 (B-1): sc-5280,可查看有标记的 Ku86 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRPm-IgGκ BP-HRP 是 Ku86 抗体 (Ku15) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与Ku86 抗体 (Ku15) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

Ku蛋白定位于核内,由Ku70(p70)和Ku86(p86)两个亚基组成,也被称为Ku80或(p80)。Ku最初被描述为一种抗原,在硬皮病多肌炎重叠综合征患者体内产生抗体,后来又在其他风湿病患者血清中发现。Ku蛋白的两个亚基已被克隆,并且已提出了许多功能,包括细胞信号传导、DNA复制和转录激活。Ku参与Pol II导向的转录,凭借其DNA结合能力,作为与DNA相关的蛋白激酶的调节组分,对Pol II和转录因子Sp进行磷酸化。Ku蛋白还能激活U1小核RNA和人转铁蛋白受体基因启动子的转录。一种被称为增强子1结合因子(E1BF)的Ku相关蛋白,由两个亚基组成,被识别为RNA聚合酶I转录启动的正调节因子。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

Ku86 抗体 (Ku15)

sc-33653
200 µg/ml
$316.00

Ku86 (Ku15): m-IgG Fc BP-HRP 套装

sc-536769
200 µg Ab; 10 µg BP
$354.00

Ku86 (Ku15): m-IgGκ BP-HRP 套装

sc-533933
200 µg Ab; 40 µg BP
$354.00

Ku86 (Ku15): m-IgG1 BP-HRP 套装

sc-544810
200 µg Ab; 20 µg BP
$354.00

Is there a trial size available for this antibody?

Asked by: AndyP
Thank you for your question. Unfortunately we do not offer samples of this monoclonal antibody. For Ku86 we offer samples of sc-5280 and sc-515736.
Answered by: Tech Service
Date published: 2019-02-22

What is the recommended fixation method for immunofluorescence staining with Ku-86 (Ku15): sc-33653 monoclonal antibody?

Asked by: jenniferc
Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10°C methanol and allowing to air dry. The full protocol can be viewed here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
Answered by: Technical Support
Date published: 2017-03-01
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Rated 4 out of 5 by from Positive detection of the KuPositive detection of the Ku-86 protein observed by WB using A-431, HeLa and C32 whole cell lysates. -SCBT QC
Date published: 2015-02-11
Rated 4 out of 5 by from Published WB and IF data with human M059K cellsPublished WB and IF data with human M059K cells - SCBT Publication Review
Date published: 2015-01-29
Rated 4 out of 5 by from Wonderful immunofluorescence nuclear stainingWonderful immunofluorescence nuclear staining in methanol-fixed HeLa cells. -SCBT QC
Date published: 2013-08-11
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Ku86 抗体 (Ku15) is rated 4.0 out of 5 by 3.
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