Date published: 2025-9-8

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Ku86 抗体 (5D5.8): sc-53021

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说明书
  • Ku86抗体(5D5.8)是小鼠单克隆IgG1 κ, 在1篇文献中引用,规格为200 µg/ml
  • 针对HeLa细胞提取物
  • 推荐用于 human 来源的Ku86 WB, IP 和 IF检测
  • 看 Ku86 (B-1): sc-5280,可查看有标记的 Ku86 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是Ku86 Antibody (5D5.8) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Ku86 Antibody (5D5.8) 打包提供(请参阅下面的订购信息)。

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Ku86抗体(5D5.8)是一种小鼠单克隆IgG1抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)和免疫荧光(IF)等方法检测人体样本中的Ku86。Ku86,也称为Ku80或p80,是Ku蛋白复合物的重要组成部分,主要位于细胞核中,由两个亚基组成:Ku70(p70)和Ku86(p86)。抗Ku86抗体(5D5.8)可识别一种在DNA修复和维护中发挥关键作用的蛋白质,特别是在非同源末端连接(NHEJ)途径中,该途径对于修复DNA双链断裂至关重要。Ku86可维持基因组的稳定性,因为基因组缺陷会导致癌症和其他遗传疾病的易感性增加。此外,Ku86通过与各种转录因子和RNA聚合酶相互作用来调节转录,从而影响基因表达。Ku86能够与DNA结合并促进修复蛋白的募集,这凸显了其在细胞对DNA损伤的反应中的重要性,使得抗Ku86抗体(5D5.8)成为研究DNA修复机制和相关途径的研究人员的重要工具。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

Ku86 抗体 (5D5.8)

sc-53021
200 µg/ml
RMB2377.00

Ku86 (5D5.8): m-IgG Fc BP-HRP 套装

sc-536870
200 µg Ab; 10 µg BP
RMB2662.00

Ku86 (5D5.8): m-IgGκ BP-HRP 套装

sc-534038
200 µg Ab; 40 µg BP
RMB2662.00

Ku86 (5D5.8): m-IgG1 BP-HRP 套装

sc-544870
200 µg Ab; 20 µg BP
RMB2662.00

I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with Ku-86 (5D5.8): sc-53021?

Asked by: TinTin
We recommend using one of our our exclusive Mouse IgG Binding Proteins conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support
Date published: 2017-02-27
  • y_2025, m_9, d_7, h_4CST
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Rated 4 out of 5 by from Crisp strong bands observed by WB using ACrisp strong bands observed by WB using A-431, HeLa and K-562 whole cell lysates. -SCBT QC
Date published: 2015-02-11
Rated 4 out of 5 by from Positive detection of endogenous expressionPositive detection of endogenous expression levels of the Ku-86 protein by WB using A-431, HeLa and C32 nuclear extracts and whole cell lysates. -SCBT QC
Date published: 2014-05-19
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Ku86 抗体 (5D5.8) is rated 4.0 out of 5 by 2.
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