Date published: 2025-9-7

021-6093-6350

SCBT Portrait Logo
Seach Input

KLF16 抗体 (F-4): sc-377519

5.0(1)
寫評論提問

说明书
  • KLF16 抗体 F-4 是小鼠单克隆 IgG1 κ,KLF16抗体, 在4篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列207-252位于human物种的KLF16的C-terminus
  • KLF16 抗体 (F-4) 推荐用于WB, IP, IF 和 ELISA,检测human 来源的 KLF16
  • 抗KLF16抗体(F-4)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取KLF16 (F-4): sc-377519免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是KLF16 Antibody (F-4) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与KLF16 Antibody (F-4) 打包提供(请参阅下面的订购信息)。

快捷链接

関連項目

KLF16抗体(F-4)是一种IgG1 κ型小鼠单克隆KLF16抗体,可通过WB、IP、IF和ELISA检测人源KLF16蛋白。KLF16抗体(F-4)既可以是非偶联型抗KLF16抗体形式,也可以是多种偶联型抗KLF16抗体形式,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。Krüppel样因子(KLFs)是一个进化上保守的含锌指转录因子家族,在细胞生长、增殖、分化和胚胎发育中具有多种调控功能。Sp1样/KLF家族的单个成员可以根据其结合的启动子和与之相互作用的核心调控因子,发挥激活或抑制作用。KLF16(Krüppel样因子16),也称为BTEB4、DRRF(多巴胺受体调节因子)或NSLP2,是一个由252个氨基酸组成的蛋白质,含有三个C2H2型锌指,属于KLF转录因子家族。KLF16定位于细胞核,在大脑中高水平表达,作为转录因子,特异性结合GT和GC盒,取代转录因子Sp1和Sp3,有效调节大脑中的多巴胺能传递。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

KLF16 抗体 (F-4) 参考文献:

  1. 多巴胺受体调节因子 DRRF:一种锌指转录因子。  |  Hwang, CK., et al. 2001. Proc Natl Acad Sci U S A. 98: 7558-63. PMID: 11390978
  2. 一个保守的α-螺旋结构介导了 Sp1 样转录抑制因子与核心抑制因子 mSin3A 的相互作用。  |  Zhang, JS., et al. 2001. Mol Cell Biol. 21: 5041-9. PMID: 11438660
  3. 锌指转录因子 DRRF(多巴胺受体调节因子)的发育表达。  |  D'Souza, UM., et al. 2002. Mech Dev. 110: 197-201. PMID: 11744383
  4. 对基本转录元件(BTE)结合蛋白(BTEB)3和新型 Sp1 样蛋白 BTEB4 的功能分析揭示了细胞色素 P4501A1 基因启动子 BTE 位点的转录抑制亚家族。  |  Kaczynski, JA., et al. 2002. Biochem J. 366: 873-82. PMID: 12036432
  5. 小鼠多巴胺受体调节因子(DRRF)基因的基因组结构和启动子特征。  |  Lee, SH., et al. 2003. Gene. 304: 193-9. PMID: 12568728
  6. 人眼表面细胞和组织特异性表达的人 Krüppel 样转录因子。  |  Chiambaretta, F., et al. 2004. Mol Vis. 10: 901-9. PMID: 15570219
  7. 鉴定正在经历人类特异性加速进化的印记 KLF14 转录因子。  |  Parker-Katiraee, L., et al. 2007. PLoS Genet. 3: e65. PMID: 17480121
  8. 分析 2 型糖尿病中的 KLF 转录因子家族基因变异。  |  Gutiérrez-Aguilar, R., et al. 2007. BMC Med Genet. 8: 53. PMID: 17688680
  9. F-box/LRR-repeat蛋白7与阿尔茨海默病存在遗传关联。  |  Tosto, G., et al. 2015. Ann Clin Transl Neurol. 2: 810-20. PMID: 26339675
  10. F-Box蛋白与癌症。  |  Yumimoto, K., et al. 2020. Cancers (Basel). 12: PMID: 32429232
  11. 仅F盒蛋白9及其在癌症中的作用。  |  Hussain, S., et al. 2022. Mol Biol Rep. 49: 1537-1544. PMID: 35025031
  12. 针对F盒蛋白的抑制剂。  |  Naseem, Y., et al. 2023. Cell Biochem Biophys. 81: 577-597. PMID: 37624574

订购信息

产品名称产品编号规格价格数量收藏夹

KLF16 抗体 (F-4)

sc-377519
200 µg/ml
RMB2377.00

KLF16 (F-4): m-IgG Fc BP-HRP 套装

sc-530033
200 µg Ab; 10 µg BP
RMB2662.00

KLF16 (F-4): m-IgGκ BP-HRP 套装

sc-523354
200 µg Ab, 40 µg BP
RMB2662.00

KLF16 (F-4): m-IgG1 BP-HRP 套装

sc-543829
200 µg Ab; 20 µg BP
RMB2662.00

KLF16 抗体 (F-4) AC

sc-377519 AC
500 µg/ml, 25% agarose
RMB3129.00

KLF16 抗体 (F-4) HRP

sc-377519 HRP
200 µg/ml
RMB2377.00

KLF16 抗体 (F-4) FITC

sc-377519 FITC
200 µg/ml
RMB2482.00

KLF16 抗体 (F-4) PE

sc-377519 PE
200 µg/ml
RMB2580.00

KLF16 抗体 (F-4) Alexa Fluor® 488

sc-377519 AF488
200 µg/ml
RMB2685.00

KLF16 抗体 (F-4) Alexa Fluor® 546

sc-377519 AF546
200 µg/ml
RMB2685.00

KLF16 抗体 (F-4) Alexa Fluor® 594

sc-377519 AF594
200 µg/ml
RMB2685.00

KLF16 抗体 (F-4) Alexa Fluor® 647

sc-377519 AF647
200 µg/ml
RMB2685.00

KLF16 抗体 (F-4) Alexa Fluor® 680

sc-377519 AF680
200 µg/ml
RMB2685.00

KLF16 抗体 (F-4) Alexa Fluor® 790

sc-377519 AF790
200 µg/ml
RMB2685.00

Will this antibody (sc-377519) work on mouse tissue samples? Have you checked whether it works?

Asked by: takk
Thank you for your question. We have not yet tested this antibody, KLF16 (F-4): sc-377519, on mouse samples, so it is not currently recommended for this species. For a limited time, we are offering a free 10 µg sample of this antibody if you would like to test it in your samples. Please contact our Technical Service Department to request a sample. Please call our Asian Support office toll-free at 800-820-8626, email [email protected], or contact us by live chat.
Answered by: Technical Support
Date published: 2017-07-20

I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with KLF16 (F-4): sc-377519?

Asked by: AbPolly
We recommend using one of our our exclusive Mouse IgG Binding Proteins conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support
Date published: 2017-02-27
  • y_2025, m_9, d_7, h_4CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_377519, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 104ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Satisfactory Western Blot data of KLF16 expressionSatisfactory Western Blot data of KLF16 expression in non-transfected and human KLF16 transfected 293T whole cell lysates. -SCBT QC
Date published: 2013-04-15
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_zh_CN, sid_377519, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 10ms
  • REVIEWS, PRODUCT
KLF16 抗体 (F-4) is rated 5.0 out of 5 by 1.
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_zh_CN, sid_377519, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 97ms
  • REVIEWS, PRODUCT