Kanamycin B sulfate CAS: 29701-07-3
MF: C18H37N5O10•H2SO4
MW: 581.59
Highly potent antibiotic against Gram-negative bacteria often used in cell culture.

Kanamycin B sulfate (CAS 29701-07-3)

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Alternate Names: Bekanamycinsulfate salt
Application: Kanamycin B sulfate is highly potent antibiotic against Gram-negative bacteria often used in cell culture
CAS Number: 29701-07-3
Purity: ≥95%
Molecular Weight: 581.59
Molecular Formula: C18H37N5O10•H2SO4
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).
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Kanamycin B is an aminoglycoside with antibiotic properties that associates with bacterial ribosomal RNA. The compound is highly potent against gram-negative bacteria. Other members of the aminoglycoside group include Kanamycin A (sc-205358) and Amikacin (sc-202457). Kanamycin B has five amino groups and has a stronger association with acidic phospholipids in comparison to Kanamycin A. Studies have shown that the Kcat value of the kanamycin group is higher compared to the neomycin group.


参考文献

1. Basak, K. and Majumdar, S.K. 1973. Antimicrob. Agents Chemother. 4: 6-10. PMID: 4791483
2. Yung, M.W. and Green, C. 1987. J. Antibiot. 40: 862-867. PMID: 3610836
3. Carrier, D., et al. 1997. Biochem. Pharmacol. 53: 401-408. PMID: 9065744
4. Kwon, M., et al. 2001. Mol. Cells. 11: 303-311. PMID: 11459219
5. Norris, A.L., et al. 2010. Biochemistry. 49: 4027-4035. PMID: 20387903

Appearance :
Crystalline powder
Physical State :
Solid
Derived From :
Streptomyces kanamyceticus
Solubility :
Soluble in water (50 mg/ml), and aqueous solution (92.3 mg/ml).
Storage :
Store at -20° C
Boiling Point :
807.7° C at 760 mmHg (Predicted)
Refractive Index :
n20D 1.67 (Predicted)
IC50 :
Bacillus subtilis: IC50 = 0.39 ug.mL-1; Staphylococcus aureus: IC50 = 1.56 ug.mL-1; Mycobacterium tuberculosis: IC50 = 2.5 ug.mL-1; Escherichia coli: IC50 = 3.13 ug.mL-1; Pseudomonas aeruginosa: IC50 = 3.13 ug.mL-1
仅供科研使用。不可用于诊断或治疗。
RTECS :
WK1976500
PubChem CID :
169075
Merck Index :
14: 5281
EC Number :
225-170-5

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