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IRF3 抗体 (D-3): sc-376455

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说明书
  • IRF3抗体(D-3)是小鼠单克隆IgG1 κ, 在17篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的IRF-3的C-terminus附近的氨基酸389-427之间
  • 抗-IRF3 抗体 (D-3) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 IRF-3
  • 抗IRF3抗体(D-3)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 可用于ChIP的TransCruz试剂(sc-376455 X, 200 µg/0.1 ml)
  • 关于如何获取IRF3 (D-3): sc-376455免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP 是 IRF3 抗体 (D-3) 在 WB and IHC(P) 应用中的首选二抗检测试剂。该试剂现与IRF3 抗体 (D-3) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

IRF-3抗体(D-3)是一种IgG1κ小鼠单克隆IRF-3抗体,可通过WB、IP、IF、IHC(P)和ELISA检测小鼠、大鼠和人源的IRF-3。IRF-3抗体(D-3)可作为非偶联抗IRF-3抗体形式,以及多种偶联形式的抗IRF-3抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。干扰素调节因子-1(IRF-1)和IRF-2已被鉴定为新型DNA结合因子,它们是I型干扰素(干扰素α和β)和干扰素诱导基因的调节因子。这两个因子在结构上相关,特别是在它们的N末端区域,这赋予了DNA结合特异性。此外,它们都与干扰素α和干扰素β基因启动子中的相同序列结合。IRF-1作为干扰素转录的激活剂,而IRF-2与相同的顺式元件结合并抑制IRF-1的作用。据报道,IRF-1和IRF-2在调节细胞生长方面相互拮抗;过渡表达抑制因子IRF-2的过表达导致细胞转化,而同时过表达IRF-1则导致逆转。IRF-1和IRF-2是更大的DNA结合蛋白家族的成员,包括IRF-3、IRF-4、IRF-5、IRF-6、IRF-7、ISGF-3γp48和干扰素共定位序列结合蛋白(ICSBP)。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

IRF3 抗体 (D-3) 参考文献:

  1. 干扰素调节因子:下一代。  |  Mamane, Y., et al. 1999. Gene. 237: 1-14. PMID: 10524230
  2. 证明核因子 IRF-1 对人类 IFN-beta 基因调控元件具有诱导和沉默特性。  |  Fujita, T., et al. 1988. EMBO J. 7: 3397-405. PMID: 2850164
  3. 干扰素调节因子 1(IRF-1)和 IRF-2 的识别 DNA 序列,它们是细胞生长和干扰素系统的调节因子。  |  Tanaka, N., et al. 1993. Mol Cell Biol. 13: 4531-8. PMID: 7687740
  4. Jak-STAT 通路和转录激活对 IFNs 及其他细胞外信号蛋白的反应。  |  Darnell, JE., et al. 1994. Science. 264: 1415-21. PMID: 8197455
  5. 鉴定干扰素调节因子家族的一个成员,它能与干扰素刺激反应元件结合并激活干扰素诱导基因的表达。  |  Au, WC., et al. 1995. Proc Natl Acad Sci U S A. 92: 11657-61. PMID: 8524823

订购信息

产品名称产品编号规格价格数量收藏夹

IRF3 抗体 (D-3)

sc-376455
200 µg/ml
RMB2377.00

IRF3 (D-3): m-IgG Fc BP-HRP 套装

sc-526034
200 µg Ab; 10 µg BP
RMB2662.00

IRF3 抗体 (D-3) X

sc-376455 X
200 µg/0.1 ml
RMB2377.00

IRF3 抗体 (D-3) AC

sc-376455 AC
500 µg/ml, 25% agarose
RMB3129.00

IRF3 抗体 (D-3) HRP

sc-376455 HRP
200 µg/ml
RMB2377.00

IRF3 抗体 (D-3) FITC

sc-376455 FITC
200 µg/ml
RMB2482.00

IRF3 抗体 (D-3) PE

sc-376455 PE
200 µg/ml
RMB2580.00

IRF3 抗体 (D-3) Alexa Fluor® 488

sc-376455 AF488
200 µg/ml
RMB2685.00

IRF3 抗体 (D-3) Alexa Fluor® 546

sc-376455 AF546
200 µg/ml
RMB2685.00

IRF3 抗体 (D-3) Alexa Fluor® 594

sc-376455 AF594
200 µg/ml
RMB2685.00

IRF3 抗体 (D-3) Alexa Fluor® 647

sc-376455 AF647
200 µg/ml
RMB2685.00

IRF3 抗体 (D-3) Alexa Fluor® 680

sc-376455 AF680
200 µg/ml
RMB2685.00

IRF3 抗体 (D-3) Alexa Fluor® 790

sc-376455 AF790
200 µg/ml
RMB2685.00

IRF3 (D-3) 中和勝肽

sc-376455 P
100 µg/0.5 ml
RMB511.00

Does IRF-3 Antibody (D-3): sc-376455 react with Porcine samples?

Asked by: Trav11
Thank you for your question. For additional species reactivity not listed on our website, please contact our Technical Service department by calling 800-457-3801 option 2, emailing [email protected], or by using the Live Chat function on our website and we will be more than happy to run sequence analysis for your species of interest.
Answered by: Technical Support 7
Date published: 2017-01-24
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Rated 4 out of 5 by from It works for IF on cellsThis Ab worked at a dil 1:100 in IF on cells (LLC-MK2)
Date published: 2023-06-29
Rated 5 out of 5 by from Good antibodyThis antibody works well in western blot of whole cell extracts prepared from several human cell lines.
Date published: 2021-05-31
Rated 4 out of 5 by from Good antibodyThis antibody worked very well with fixed frozen mouse tissue sections for IF
Date published: 2018-10-03
Rated 5 out of 5 by from good for ChIPI bought this antibody for ChIP assay, and I got the enrichment signal!!!
Date published: 2018-01-30
Rated 5 out of 5 by from Excellent choice for IHC(P)IRF-3 clone D-3 is an excellent choice for IHC(P).
Date published: 2016-12-23
Rated 5 out of 5 by from Clean blot and single band for WB in human IRFClean blot and single band for WB in human IRF-3 transfected 293T whole cell lysates. -SCBT QC
Date published: 2015-02-25
Rated 5 out of 5 by from Worked formalin fixedWorked formalin fixed, paraffin-embedded human testis tissue, cytoplasmic staining of cells in seminiferous ducts and Leydig cells was showed. -SCBT QC
Date published: 2014-04-26
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IRF3抗体 (D-3) is rated 4.8 out of 5 by 8.
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