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INSR/Insulin Receptor β 抗体 (29B4): sc-09

4.8(4)
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说明书
  • INSR/Insulin Receptor β 抗体 29B4 是小鼠单克隆 IgG1, 在60篇文献中引用,提供 100 µg/ml
  • 表位定位到95 kDa β链的细胞内区域,该链来自human胰岛素受体
  • 推荐用于 mouse, rat 和 human 来源的insulin Rβ chain WB, IP 和 KA检测; 不建议用于WB
  • 目前,我们还没有完成INSR/Insulin Receptor β 抗体 (29B4)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

胰岛素Rβ抗体(29B4)是一种小鼠单克隆IgG1抗体,用于识别人类胰岛素受体95 kDa β链上的细胞内表位。胰岛素受体是一种重要的跨膜蛋白复合物,位于细胞表面,通过结合胰岛素并触发重要的信号通路,在调节葡萄糖摄取和代谢方面发挥着关键作用。胰岛素受体的β亚基位于细胞质内,其固有的酪氨酸激酶活性对于磷酸化细胞内底物和传播胰岛素信号至关重要,从而促进葡萄糖转运和糖原合成等过程。了解β亚基的定位和功能对于阐明胰岛素的作用机制和代谢紊乱中胰岛素抵抗的发展至关重要。胰岛素Rβ(29B4)单克隆抗体适用于多种物种(包括小鼠、大鼠和人类)的免疫沉淀(IP)和激酶检测(KA),是各种模型系统研究的多功能工具。胰岛素Rβ(29B4)抗体支持胰岛素信号通路的研究,为1型和2型糖尿病等疾病的分子基础提供了见解。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

INSR/Insulin Receptor β 抗体 (29B4)

sc-09
100 µg/ml
RMB2504.00

I am considering using this antibody for structural studies and would like to know more about the epitope, so if you can give me as much information as possible it would be highly appreciated.

Asked by: JN20
Thank you for your question. The exact epitope recognized by this mouse monoclonal antibody has not yet been determined.
Answered by: Technical Support
Date published: 2019-01-31

What is the recommended storage condition for insulin Rβ (29B4): sc-09?

Asked by: Trav11
Thank you for your question. We recommend storing the antibody at 4° C.
Answered by: Technical Support
Date published: 2017-03-27
  • y_2025, m_9, d_7, h_4CST
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Rated 5 out of 5 by from Shows good IP of transfected rat HTC cellsShows good IP of transfected rat HTC cells labeled with Met-s35. The antibody will also detect a bond at 190 kDa, aside from the 95 kDa b chain, which represents the precursor form of the receptor.
Date published: 2015-04-20
Rated 4 out of 5 by from Worked well for IP/WB on human peripheralWorked well for IP/WB on human peripheral blood mononuclear cells (PBMC). -SCBT Publication Review
Date published: 2015-02-14
Rated 5 out of 5 by from Positive results using 29B4 to immunoprecipitatePositive results using 29B4 to immunoprecipitate insulin R . -SCBT QC
Date published: 2015-01-23
Rated 5 out of 5 by from WB: works with rat liver lysateWB: works with rat liver lysate. -SCBT Publication Review
Date published: 2013-02-17
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INSR/Insulin Receptor β 抗体 (29B4) is rated 4.8 out of 5 by 4.
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