Date published: 2025-9-11
访问圣克鲁斯动物健康

021-6093-6350

SCBT Portrait Logo
Seach Input
联系我们
登陆账户
快速订购
购物车 (0)
Influenza A m2 Antibody (14C2) - Western Blotting - Image 11590
甲型流感 m2 抗体 (14C2): sc-32238. 甲型流感病毒 m2 蛋白的 Western 印迹分析.
Influenza A m2 Antibody (14C2) - Western Blotting - Image 11590
甲型流感 m2 抗体 (14C2): sc-32238. 甲型流感病毒 m2 蛋白的 Western 印迹分析.
甲型流感 m2 抗体 (14C2): sc-32238. 甲型流感病毒 m2 蛋白的 Western 印迹分析.

Influenza A m2 抗体 (14C2): sc-32238

4.1(12)
寫評論提問

说明书
  • Influenza A m2 抗体 14C2 是小鼠单克隆 IgG1 κ，Influenza A m2抗体, 在49篇文献中引用，规格为200 µg/ml
  • 针对从感染WSN/33的CV1细胞裂解液中纯化的M2蛋白
  • Influenza A m2 抗体 (14C2) 推荐用于WB, IP, IF 和 IHC(P)，检测Influenza A protein m2 来源的 Influenza A m2
  • 抗Influenza A m2抗体（14C2）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Influenza A m2 (14C2): sc-32238的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG1 BP-HRP 是 Influenza A m2 抗体 (14C2) 在 WB and IHC(P) 应用中的首选二抗检测试剂。该试剂现与Influenza A m2 抗体 (14C2) 组合成套装提供。 (请参阅下面的订购信息)。

快捷链接

相关产品
描述
说明书与实验方案
研究信息

関連項目

此外 Influenza 抗体 包括 Influenza A m1, Influenza A m2, Influenza A NP, Influenza A ns1, Influenza A Virus Hemagglutinin, Influenza B, Influenza B M1, Influenza B NA和Influenza B NP

甲型流感病毒m2抗体（14C2）是一种小鼠单克隆IgG1 kappa轻链抗体，可通过蛋白质印迹（WB）、免疫沉淀（IP）、免疫荧光（IF）和免疫组织化学检测甲型流感病毒m2蛋白。抗甲型流感病毒m2抗体（14C2）有非结合型和多种结合型，包括琼脂糖、辣根过氧化物酶（HRP）、藻红蛋白（PE）、异硫氰酸荧光素（FITC）和多种Alexa Fluor®结合物。甲型流感病毒M2蛋白在病毒生命周期中起着至关重要的作用，它充当质子通道，促进病毒内部的酸化，这对感染过程中的解包膜过程至关重要。甲型流感病毒M2蛋白能够形成高度选择性、pH值调节通道，使质子进入病毒，导致pH值降低，从而破坏基质蛋白M1与核糖核蛋白复合物之间的相互作用。这种破坏对于将病毒RNA释放到宿主细胞中至关重要，最终实现病毒复制。了解甲型流感病毒M2蛋白的功能对于制定抗病毒策略非常重要，因为该靶标为治疗流感感染提供了机会。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Influenza A m2 抗体 (14C2) 参考文献:

  1. 基于实验的膜蛋白模型定向细化：甲型流感 M2 H+ 通道的结构。  |  Kukol, A., et al. 1999. J Mol Biol. 286: 951-62. PMID: 10024461
  2. 甲型流感病毒 M（2）离子通道的质子传导机制。  |  Mould, JA., et al. 2000. J Biol Chem. 275: 8592-9. PMID: 10722698
  3. 流感病毒组装：流感病毒糖蛋白对 M1 蛋白膜缔合作用的影响。  |  Ali, A., et al. 2000. J Virol. 74: 8709-19. PMID: 10954572
  4. 流感和其他病毒性肺炎的最新情况。  |  Fleming, DM. and Zambon, M. 2001. Curr Opin Infect Dis. 14: 199-204. PMID: 11979133
  5. 甲型流感 M2 蛋白的构象取决于模型膜的选择。  |  Saotome, K., et al. 2015. Biopolymers. 104: 405-11. PMID: 25652904
  6. 六亚甲基氨苯蝶啶衍生的新型甲型/乙型流感病毒抑制剂的作用机制。  |  Jalily, PH., et al. 2016. Mol Pharmacol. 90: 80-95. PMID: 27193582
  7. 作为甲型流感 M2 抑制剂的二价铜复合物。  |  Gordon, NA., et al. 2017. Antiviral Res. 147: 100-106. PMID: 29032206
  8. 甲型流感 M2 蛋白的远端细胞质尾部从膜上动态延伸出来。  |  Kim, G., et al. 2019. Biochim Biophys Acta Biomembr. 1861: 1421-1427. PMID: 31153909
  9. 阻断甲型流感 M2 野生型和 S31N 通道的化学探针。  |  Tzitzoglaki, C., et al. 2020. ACS Chem Biol. 15: 2331-2337. PMID: 32786258
  10. 通过过量质子稳定和通道动力学机制了解甲型流感 M2 抑制剂的结合。  |  Watkins, LC., et al. 2020. J Am Chem Soc. 142: 17425-17433. PMID: 32933245
  11. 甲型流感 M2 将 M1 募集到质膜上：荧光波动显微镜研究。  |  Petrich, A., et al. 2021. Biophys J. 120: 5478-5490. PMID: 34808098
  12. 甲型流感病毒 M2 质子通道的功能定义模型表明了其离子选择性的机制。  |  Pinto, LH., et al. 1997. Proc Natl Acad Sci U S A. 94: 11301-6. PMID: 9326604

订购信息

产品名称产品编号规格价格数量收藏夹

Influenza A m2 抗体 (14C2)

sc-32238
200 µg/ml
RMB2377.00

Influenza A m2 (14C2): m-IgG1 BP-HRP 套装

sc-531642
200 µg Ab; 20 µg BP
RMB2662.00

Influenza A m2 抗体 (14C2) AC

sc-32238 AC
500 µg/ml, 25% agarose
RMB3129.00

Influenza A m2 抗体 (14C2) HRP

sc-32238 HRP
200 µg/ml
RMB2377.00

Influenza A m2 抗体 (14C2) FITC

sc-32238 FITC
200 µg/ml
RMB2482.00

Influenza A m2 抗体 (14C2) PE

sc-32238 PE
200 µg/ml
RMB2580.00

Influenza A m2 抗体 (14C2) Alexa Fluor® 488

sc-32238 AF488
200 µg/ml
RMB2685.00

Influenza A m2 抗体 (14C2) Alexa Fluor® 546

sc-32238 AF546
200 µg/ml
RMB2685.00

Influenza A m2 抗体 (14C2) Alexa Fluor® 594

sc-32238 AF594
200 µg/ml
RMB2685.00

Influenza A m2 抗体 (14C2) Alexa Fluor® 647

sc-32238 AF647
200 µg/ml
RMB2685.00

Influenza A m2 抗体 (14C2) Alexa Fluor® 680

sc-32238 AF680
200 µg/ml
RMB2685.00

Influenza A m2 抗体 (14C2) Alexa Fluor® 790

sc-32238 AF790
200 µg/ml
RMB2685.00

Is the antibody generated by using the whole M2 protein as immunogen? Because I need to detect the bat flu H17N10 and H18N11 M2, but the bat flu M2 share only 50% identity with conventional flu A M2. Thus, whole M2 protein as immunogen give me more chance

Asked by: Rebecca Livia
Thank you for your question. It would be helpful if you could call 800-457-3801, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Service
Date published: 2022-04-29

What secondary is best to use with Influenza A m2 Antibody (14C2): sc-32238?

Asked by: jenni
Thank you for your question. While most anti-mouse IgG secondary antibodies are appropriate for use with our Influenza A m2 (14C2): sc-32238, we recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support 10
Date published: 2024-02-06
  • y_2025, m_9, d_7, h_4CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_32238, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 107ms
  • QUESTIONS, PRODUCT
Rated 4 out of 5 by from Gute Ergebnisse in IFA und Flow CytometryErkennt WSN wie versprochen. Der Antikörper ist zu empfehlen
Date published: 2018-04-10
Rated 4 out of 5 by from Works for Immunofluorescence in A549 cellsWorked for Immunofluorescence in A549 cells. Infected the cells with Cal2009 H1N1 strain. Dilution 1:100
Date published: 2017-09-11
Rated 5 out of 5 by from strong bandsWhen diluted 1:500 signal is strong, we are very satisfied with his ability to work
Date published: 2017-05-14
Rated 5 out of 5 by from Robust bandWe are happy to use this antibody for western blot, showed a clear band of diluted 1:500.
Date published: 2017-04-25
Rated 5 out of 5 by from clean resultsClean WB data. Direct conjugates great--no need for secondary antibodies.
Date published: 2017-01-11
Rated 4 out of 5 by from Got strong band at 1:200 in WBGot strong band at 1:200 in WB.
Date published: 2015-09-21
Rated 5 out of 5 by from Good IP in canine infected MDCK cellsGood IP in canine infected MDCK cells.
Date published: 2015-07-20
Rated 5 out of 5 by from Very good signal by WB in canine infectedVery good signal by WB in canine infected MDCK cells.
Date published: 2015-07-20
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_12
  • loc_zh_CN, sid_32238, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 19ms
  • REVIEWS, PRODUCT
Influenza A m2 抗体 (14C2) is rated 4.1 out of 5 by 12.
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_12
  • loc_zh_CN, sid_32238, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 108ms
  • REVIEWS, PRODUCT
021-6093-6350
访问 Santa Cruz Animal Health|访问 San Juan Ranch
Santa Cruz Biotechnology, Inc. 是生物医学研究市场产品开发的世界领导者。请拨打0086-021-60936350联系我们。
版权所有© 2007-2025 Santa Cruz Biotechnology, Inc. 保留所有权利。”Santa Cruz Biotechnology” 和Santa Cruz Biotechnology, Inc.的商标，”Santa Cruz Animal Health”, “San Juan Ranch”, “Supplement of Champions”, San Juan Ranch的商标，”UltraCruz”, “ChemCruz”, “ImmunoCruz”, “ExactaCruz”, 和 “EZ Touch”是Santa Cruz Biotechnology, Inc.的注册商标。所有商标均为其各自所有者的财产。