INCB024360 (CAS 914471-09-3)

物理状态 :

Solid

保存 :

Store at room temperature

熔点 :

154.74° C (Predicted)

沸点 :

~318.6° C at 760 mmHg (Predicted)

密度 :

~1.8 g/cm³ (Predicted)

折射率 :

n²⁰_D 1.72 (Predicted)

IC50 :

IDO: IC₅₀ = 19 nM (human); Indoleamine 2,3-dioxygenase 1: IC₅₀ = 46 nM (mouse); TDO2: IC₅₀ >10 µM (human); Tryptophan 2,3-dioxygenase: IC₅₀ = 60 µM (mouse)

pK值 :

pK_a: 12.05 (Predicted)

PubChem CID :

SMILES :

C1=CC(=C(C=C1N/C(=C\\2/C(=NON2)N)/N=O)Cl)F