Date published: 2025-9-7

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IL-8RA 抗体 (B-1): sc-7303

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说明书
  • IL-8RA 抗体 B-1 是小鼠单克隆 IgG1 κ,IL-8RA抗体, 在10篇文献中引用,规格为200 µg/ml
  • 抗原表位位于human物种的IL-8RA的N-terminus
  • IL-8RA 抗体 (B-1) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测human 和hamster 来源的 IL-8RA
  • 抗IL-8RA抗体(B-1)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取IL-8RA (B-1): sc-7303免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRPm-IgGκ BP-HRP 是 IL-8RA 抗体 (B-1) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与IL-8RA 抗体 (B-1) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

IL-8RA抗体(B-1)是一种小鼠单克隆IgG1 kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)、石蜡包埋切片免疫组织化学(IHCP)和酶联免疫吸附测定(ELISA)检测人类和仓鼠来源的IL-8RA。IL-8RA 单克隆抗体(B-1)有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和多种 Alexa Fluor® 结合物。IL-8RA在调节炎症反应中起着至关重要的作用,它作为白细胞介素-8(IL-8)的高亲和力受体,而IL-8是一种对中性粒细胞有强烈趋化作用的因子。这种相互作用对于在炎症部位募集和激活中性粒细胞至关重要,这使得IL-8RA成为免疫反应的关键参与者,也是治疗炎症性疾病的潜在靶点。值得注意的是,IL-8RA是IL-8RB等受体家族的一员,这两种受体都具有7个跨膜结构域,这对于它们在G蛋白偶联信号转导中的作用至关重要。IL-8RA在嗜中性粒细胞上的高表达,以及其在Jurkat细胞系等T细胞中的存在,凸显了其在先天性和适应性免疫反应中的重要性。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

IL-8RA 抗体 (B-1) 参考文献:

  1. 缺氧/复氧对多形核白细胞中 IL-8RA (CXCR1) 表达的调控。  |  Grutkoski, PS., et al. 1999. J Leukoc Biol. 65: 171-8. PMID: 10088599
  2. 白细胞介素-8 是血管生成的巨噬细胞衍生介质。  |  Koch, AE., et al. 1992. Science. 258: 1798-801. PMID: 1281554
  3. 两种高亲和力人类白细胞介素-8受体的特征。  |  Lee, J., et al. 1992. J Biol Chem. 267: 16283-7. PMID: 1379593
  4. 白细胞介素 8 及相关细胞因子对人中性粒细胞质膜中 G 蛋白的激活作用  |  Kupper, RW., et al. 1992. Biochem J. 282 (Pt 2): 429-34. PMID: 1546956
  5. 白细胞介素-8 及其受体 IL-8RA 在慢性增生性念珠菌病中的表达。  |  Ali, A., et al. 2006. Oral Microbiol Immunol. 21: 223-30. PMID: 16842506
  6. 克隆编码功能性人白细胞介素-8 受体的互补 DNA。  |  Murphy, PM. and Tiffany, HL. 1991. Science. 253: 1280-3. PMID: 1891716
  7. 人类白细胞介素-8 受体的结构和功能表达。Science.1991.253: 1278-1280.  |  Holmes, WE., et al. 2009. J Immunol. 183: 2895-7. PMID: 19696428
  8. 毛细胞瘤中的IL-8、IL-8RA(CXCR1)和IL-8RB(CXCR2)表达。  |  Cianga, CM., et al. 2016. Rom J Morphol Embryol. 57: 59-64. PMID: 27151689
  9. 单克隆抗体检测人体外周血白细胞中 IL-8 受体 A 和 IL-8 受体 B 的不同分布模式。  |  Chuntharapai, A., et al. 1994. J Immunol. 153: 5682-8. PMID: 7527448
  10. 白细胞介素-8:综述。  |  Hébert, CA. and Baker, JB. 1993. Cancer Invest. 11: 743-50. PMID: 8221207
  11. 人中性粒细胞膜上白细胞介素-8受体的特征:鸟嘌呤核苷酸的调控。  |  Barnett, ML., et al. 1993. Biochim Biophys Acta. 1177: 275-82. PMID: 8323978
  12. 人类吞噬细胞, 淋巴细胞和黑色素瘤细胞中两种白细胞介素 8 受体转录本的表达。  |  Moser, B., et al. 1993. Biochem J. 294 (Pt 1): 285-92. PMID: 8363581

订购信息

产品名称产品编号规格价格数量收藏夹

IL-8RA 抗体 (B-1)

sc-7303
200 µg/ml
RMB2377.00

IL-8RA (B-1): m-IgG Fc BP-HRP 套装

sc-528172
200 µg Ab; 10 µg BP
RMB2662.00

IL-8RA (B-1): m-IgGκ BP-HRP 套装

sc-520489
200 µg Ab, 40 µg BP
RMB2662.00

IL-8RA (B-1): m-IgG1 BP-HRP 套装

sc-542798
200 µg Ab; 20 µg BP
RMB2662.00

IL-8RA 抗体 (B-1) AC

sc-7303 AC
500 µg/ml, 25% agarose
RMB3129.00

IL-8RA 抗体 (B-1) HRP

sc-7303 HRP
200 µg/ml
RMB2377.00

IL-8RA 抗体 (B-1) FITC

sc-7303 FITC
200 µg/ml
RMB2482.00

IL-8RA 抗体 (B-1) PE

sc-7303 PE
200 µg/ml
RMB2580.00

IL-8RA 抗体 (B-1) Alexa Fluor® 488

sc-7303 AF488
200 µg/ml
RMB2685.00

IL-8RA 抗体 (B-1) Alexa Fluor® 546

sc-7303 AF546
200 µg/ml
RMB2685.00

IL-8RA 抗体 (B-1) Alexa Fluor® 594

sc-7303 AF594
200 µg/ml
RMB2685.00

IL-8RA 抗体 (B-1) Alexa Fluor® 647

sc-7303 AF647
200 µg/ml
RMB2685.00

IL-8RA 抗体 (B-1) Alexa Fluor® 680

sc-7303 AF680
200 µg/ml
RMB2685.00

IL-8RA 抗体 (B-1) Alexa Fluor® 790

sc-7303 AF790
200 µg/ml
RMB2685.00

I need to use an antibody to detect the protein in samples of avian origin. Do you know if this mouse monoclonal antibody will work?

Asked by: jerojero
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support 14
Date published: 2017-02-10
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Rated 4 out of 5 by from IL8-RA For WBI do the WB in MCF7 cells and diluted it at 1:1000, a specifec band was abserved but there ara some nonspecific bands too.
Date published: 2018-04-12
Rated 4 out of 5 by from can not be used for pig tissueThis product can be used for immunohistochemistry of human tissue, can not be used for pig tissue, the positive signal in cytoplasm.
Date published: 2017-09-09
Rated 5 out of 5 by from Good dataThis antibody is reactive with human and hamster samples and will provide great data for both. Clear bands in WB and specific staining signal. It even works for FCM and has been published with before.
Date published: 2017-01-27
Rated 5 out of 5 by from Published data for IF and Flow CytometryPublished data for IF and Flow Cytometry in human LIM 1863 cells (colon carcinoma). -SCBT Publication Review
Date published: 2015-07-06
Rated 5 out of 5 by from Produced great immunoperoxidase cytoplasmicProduced great immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human skeletal muscle tissue. -SCBT QC
Date published: 2015-04-08
Rated 4 out of 5 by from Band of interest observed in WB in human ILBand of interest observed in WB in human IL-8RA transfected 293T whole cell lysate. -SCBT QC
Date published: 2015-03-27
Rated 4 out of 5 by from Positive signal observed in WB in CHO cellsPositive signal observed in WB in CHO cells transfected with IL-8RA. -SCBT QC
Date published: 2015-03-06
Rated 5 out of 5 by from Produced nice FCM data for human peripheralProduced nice FCM data for human peripheral blood leukocytes. -SCBT QC
Date published: 2013-04-23
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IL-8RA 抗体 (B-1) is rated 4.5 out of 5 by 8.
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