Date published: 2025-9-7

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IL-15Rα 抗体 (G-3): sc-374023

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说明书
  • IL-15R alpha 抗体 G-3 是小鼠单克隆 IgG2a κ,IL-15Rα抗体, 在4篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的IL-15Rα的N-terminus附近的氨基酸21-54之间
  • IL-15R alpha 抗体 (G-3) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 IL-15Rα
  • 抗IL-15R alpha抗体(G-3)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取IL-15Rα (G-3): sc-374023免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP2a BP-HRP">m-IgG2a BP-HRPm-IgGκ BP-HRP是IL-15Rα Antibody (G-3) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与IL-15Rα Antibody (G-3) 打包提供(请参阅下面的订购信息)。

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関連項目

IL-15Rα抗体(G-3)是一种IgG2a κ小鼠单克隆IL-15R alpha抗体(也称为IL-15Rα抗体),可通过WB、IP、IF和ELISA检测小鼠、大鼠和人源的IL-15R alpha蛋白。IL-15Rα抗体(G-3)既可以是非偶联的抗IL-15R alpha抗体形式,也可以是多种偶联形式的抗IL-15R alpha抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。白细胞介素-15(IL-15),也称为IL-T,是一种克隆的细胞因子,与IL-2具有多种生物学活性,但没有序列同源性。人、小鼠和猴的IL-15 cDNA克隆已被分离和表征。这三种物种都编码一个含有48个氨基酸前导序列的162个氨基酸残基前体蛋白,该前导序列被切割以生成成熟的IL-15形式。IL-15刺激T细胞和NK细胞的增殖,同时增强B细胞扩张和抗体产生。与IL-2不同,IL-15不是由淋巴细胞产生的,而是由巨噬细胞、上皮细胞、肌肉和胎盘产生的。研究还表明,IL-15是人血液T淋巴细胞的趋化因子,能够诱导NK细胞中的淋巴因子激活的杀伤细胞(LAK)活性,并能够诱导细胞溶解效应细胞的生成。研究表明,IL-15是唯一与IL-2R的β信号亚基共享的其他细胞因子。证据还表明,与IL-2、IL-4和IL-7类似,IL-15利用共同的IL-2Rγ亚基。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

IL-15Rα 抗体 (G-3) 参考文献:

  1. 白介素-15及其受体(IL-15Rα)对白塞氏病具有新的治疗意义。  |  He, Y., et al. 2014. Rheumatol Int. 34: 1173-4. PMID: 24046145
  2. 肝星状细胞上的白细胞介素-15受体α可调控小鼠的肝纤维化。  |  Jiao, J., et al. 2016. J Hepatol. 65: 344-353. PMID: 27154062
  3. IL-15和IL-15Rα基因与乳糜泻的关系。  |  Escudero-Hernández, C., et al. 2017. Cytokine. 99: 73-79. PMID: 28738233
  4. 非NK细胞来源的IFNγ驱动的利斯特菌单核细胞增生李斯特菌的IL-15Rα独立IL-15信号传导。  |  Nandi, M., et al. 2021. Front Immunol. 12: 793918. PMID: 34956227
  5. CAR-IL-15/IL-15Rα-T细胞和GLIPR1敲除在癌细胞中的联合治疗增强了胃癌的抗肿瘤作用。  |  Ye, J., et al. 2024. J Transl Med. 22: 171. PMID: 38368374
  6. 紫外线 B 辐射可上调人体皮肤中 IL-15 的表达。  |  Mohamadzadeh, M., et al. 1995. J Immunol. 155: 4492-6. PMID: 7594612
  7. Il15 的染色体分配和基因组结构。  |  Anderson, DM., et al. 1995. Genomics. 25: 701-6. PMID: 7759105
  8. IL-15 具有诱导 B 细胞增殖和分化的刺激活性。  |  Armitage, RJ., et al. 1995. J Immunol. 154: 483-90. PMID: 7814861
  9. 新型细胞因子 IL-15 对 IL-2 受体 beta 和 gamma 链的利用。  |  Giri, JG., et al. 1994. EMBO J. 13: 2822-30. PMID: 8026467
  10. 克隆出一种与白细胞介素-2 受体 beta 链相互作用的 T 细胞生长因子。  |  Grabstein, KH., et al. 1994. Science. 264: 965-8. PMID: 8178155
  11. 一种淋巴因子,暂定名为白细胞介素 T,由人类成人 T 细胞白血病系产生,可刺激 T 细胞增殖并诱导淋巴因子激活的杀伤细胞。  |  Burton, JD., et al. 1994. Proc Natl Acad Sci U S A. 91: 4935-9. PMID: 8197160
  12. 诱导和调节小鼠巨噬细胞中 IL-15 的表达。  |  Doherty, TM., et al. 1996. J Immunol. 156: 735-41. PMID: 8543827

订购信息

产品名称产品编号规格价格数量收藏夹

IL-15Rα 抗体 (G-3)

sc-374023
200 µg/ml
RMB2377.00

IL-15Rα (G-3): m-IgG Fc BP-HRP 套装

sc-529639
200 µg Ab; 10 µg BP
RMB2662.00

IL-15Rα (G-3): m-IgGκ BP-HRP 套装

sc-522593
200 µg Ab, 40 µg BP
RMB2662.00

IL-15Rα (G-3): m-IgG2a BP-HRP 套装

sc-547349
200 µg Ab; 10 µg BP
RMB2662.00

IL-15Rα 抗体 (G-3) AC

sc-374023 AC
500 µg/ml, 25% agarose
RMB3129.00

IL-15Rα 抗体 (G-3) HRP

sc-374023 HRP
200 µg/ml
RMB2377.00

IL-15Rα 抗体 (G-3) FITC

sc-374023 FITC
200 µg/ml
RMB2482.00

IL-15Rα 抗体 (G-3) PE

sc-374023 PE
200 µg/ml
RMB2580.00

IL-15Rα 抗体 (G-3) Alexa Fluor® 488

sc-374023 AF488
200 µg/ml
RMB2685.00

IL-15Rα 抗体 (G-3) Alexa Fluor® 546

sc-374023 AF546
200 µg/ml
RMB2685.00

IL-15Rα 抗体 (G-3) Alexa Fluor® 594

sc-374023 AF594
200 µg/ml
RMB2685.00

IL-15Rα 抗体 (G-3) Alexa Fluor® 647

sc-374023 AF647
200 µg/ml
RMB2685.00

IL-15Rα 抗体 (G-3) Alexa Fluor® 680

sc-374023 AF680
200 µg/ml
RMB2685.00

IL-15Rα 抗体 (G-3) Alexa Fluor® 790

sc-374023 AF790
200 µg/ml
RMB2685.00

IL-15Rα 抗体 (G-3) B

sc-374023 B
200 µg/ml
RMB2407.00

IL-15Rα (G-3) 中和勝肽

sc-374023 P
100 µg/0.5 ml
RMB511.00

Hello, could you please share with me the epitope range, or sequence of neutralizing peptide? Description says the "between amino acids 21-54", but until 30 is usually described as signal peptide, I am a bit confused. Thanks

Asked by: EvaVonPrague
Thank you for your question. It would be helpful if you could call 800-457-3801, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Service
Date published: 2023-04-19

Hi! I would like to obtain a copy of the CofA for Anti-IL-15Rα Antibody (G-3) product #sc-374023, Lot #G1421. Thanks very much! Trang

Asked by: Anonymous
Thank you for your question. It would be helpful if you could call us, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Support
Date published: 2021-07-22

What is the appropriate isotype control for IL-15Rα Antibody (G-3) FITC (sc-374023) ? Could you please provide the catalog number? Thanks.

Asked by: Joanna_W
Thank you for your question. IL-15Rα Antibody (G-3) is a mouse monoclonal IgG2a. The recommended isotype control conjugated to FITC is our normal mouse IgG2a-FITC: sc-2856.
Answered by: Technical Support
Date published: 2019-08-17

What application is the blocking peptide sc-374023 P appropriate for?

Asked by: Randy McDonald
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-25
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Rated 3 out of 5 by from Tested on HFFF by FACSThis antibody was tested on HFFF cells by FACS and gave a mild signal, even at dilution 1:25
Date published: 2018-11-16
Rated 5 out of 5 by from Produced nice Western blot data of ILProduced nice Western blot data of IL-15R expression in Raji whole cell lysate. -SCBT QC
Date published: 2014-01-15
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IL-15Rα抗体 (G-3) is rated 4.0 out of 5 by 2.
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