Date published: 2025-9-8

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IK1 抗体 (D-5): sc-365265

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说明书
  • IK1 抗体 D-5 是小鼠单克隆 IgG1 κ,IK1抗体, 在23篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列308-427位于human物种的IK1的C-terminus
  • IK1 抗体 (D-5) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 IK1
  • 抗IK1抗体(D-5)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取IK1 (D-5): sc-365265免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是IK1 Antibody (D-5) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与IK1 Antibody (D-5) 打包提供(请参阅下面的订购信息)。

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関連項目

IK1抗体(D-5)是一种IgG1 κ小鼠单克隆IK1抗体(也称为钾钙激活通道亚家族N成员4抗体、KCa3.1抗体、钾通道钙激活中间/小电导亚家族N α成员4抗体、HIKCa1抗体、SKCa 4抗体、IKCA1抗体、HKCa4抗体、SKCa4抗体、KCA4抗体、HSK4抗体、IK1抗体、SK4抗体、IK抗体、假定的红细胞中间电导钙激活钾加德纳通道抗体或中间电导钙激活钾通道抗体),可通过WB、IP、IF和ELISA检测小鼠、大鼠和人源的IK1蛋白。IK1抗体(D-5)既有非偶联抗IK1抗体形式,也有多种偶联形式的抗IK1抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。中间电导钙激活钾通道蛋白4(SK4或IK1)是KCNN钾通道家族的一个成员。IK1是一种整体膜蛋白,具有多种生理功能。IK1通道的激活由细胞内钙水平诱导,并受钙调蛋白的调节。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

IK1 抗体 (D-5) 参考文献:

  1. 结肠隐窝小型钙(2+)调节 K+ 通道(rSK4)的分子和功能特征。  |  Warth, R., et al. 1999. Pflugers Arch. 438: 437-44. PMID: 10519135
  2. 钙调蛋白调节 SK4/IK1 Ca2+ 激活的 K+ 通道的组装和运输  |  Joiner, WJ., et al. 2001. J Biol Chem. 276: 37980-5. PMID: 11495911
  3. 大鼠 SK4/IK1 K(+)通道的特征。  |  von Hahn, T., et al. 2001. Cell Physiol Biochem. 11: 219-30. PMID: 11509830
  4. SK4/IK1样通道介导牛腮腺尖锐湿疣细胞中对TEA不敏感, 由Ca2+激活的K+电流  |  Takahata, T., et al. 2003. Am J Physiol Cell Physiol. 284: C127-44. PMID: 12388063
  5. 小传导钙激活 K+ 通道在胰岛中表达并调节葡萄糖反应。  |  Tamarina, NA., et al. 2003. Diabetes. 52: 2000-6. PMID: 12882916
  6. 大鼠下颌下腺吖丙腺细胞 SK4/IK1 类电流的 ATP 依赖性调节:cAMP 依赖性蛋白激酶的可能作用  |  Hayashi, M., et al. 2004. Am J Physiol Cell Physiol. 286: C635-46. PMID: 14602578
  7. 一氧化氮通过亚硝基化 Kir2.1 通道的半胱氨酸 76 增加心脏 IK1。  |  Gómez, R., et al. 2009. Circ Res. 105: 383-92. PMID: 19608980
  8. 缺血再灌注期间醛固酮对 IK1 的快速和 MR 依赖性激活  |  Alexandre, J., et al. 2015. PLoS One. 10: e0132592. PMID: 26222262
  9. IK1 通道对锥体神经元的缓慢后超极化没有贡献。  |  Wang, K., et al. 2016. Elife. 5: e11206. PMID: 26765773
  10. IK1增强的人类诱导多能干细胞衍生心肌细胞:研究遗传性心律失常综合征的改良心肌细胞模型。  |  Vaidyanathan, R., et al. 2016. Am J Physiol Heart Circ Physiol. 310: H1611-21. PMID: 27059077
  11. IK1/Kir2.1通道激动剂扎科必利可预防和治疗大鼠急性缺血性心律失常。  |  Zhai, XW., et al. 2017. PLoS One. 12: e0177600. PMID: 28542320
  12. 利用硅学 IK1 电流的动态钳夹方法来区分心室特异性 hiPsc 衍生心肌细胞。  |  Altomare, C., et al. 2023. Commun Biol. 6: 291. PMID: 36934210

订购信息

产品名称产品编号规格价格数量收藏夹

IK1 抗体 (D-5)

sc-365265
200 µg/ml
RMB2377.00

IK1 (D-5): m-IgG Fc BP-HRP 套装

sc-529340
200 µg Ab; 10 µg BP
RMB2662.00

IK1 (D-5): m-IgGκ BP-HRP 套装

sc-522186
200 µg Ab, 40 µg BP
RMB2662.00

IK1 (D-5): m-IgG1 BP-HRP 套装

sc-543466
200 µg Ab; 20 µg BP
RMB2662.00

IK1 抗体 (D-5) AC

sc-365265 AC
500 µg/ml, 25% agarose
RMB3129.00

IK1 抗体 (D-5) HRP

sc-365265 HRP
200 µg/ml
RMB2377.00

IK1 抗体 (D-5) FITC

sc-365265 FITC
200 µg/ml
RMB2482.00

IK1 抗体 (D-5) PE

sc-365265 PE
200 µg/ml
RMB2580.00

IK1 抗体 (D-5) Alexa Fluor® 488

sc-365265 AF488
200 µg/ml
RMB2685.00

IK1 抗体 (D-5) Alexa Fluor® 546

sc-365265 AF546
200 µg/ml
RMB2685.00

IK1 抗体 (D-5) Alexa Fluor® 594

sc-365265 AF594
200 µg/ml
RMB2685.00

IK1 抗体 (D-5) Alexa Fluor® 647

sc-365265 AF647
200 µg/ml
RMB2685.00

IK1 抗体 (D-5) Alexa Fluor® 680

sc-365265 AF680
200 µg/ml
RMB2685.00

IK1 抗体 (D-5) Alexa Fluor® 790

sc-365265 AF790
200 µg/ml
RMB2685.00

I need to use an antibody to detect the protein in samples of bovine origin. Do you know if sc-365265: IK1 (D-5) mouse monoclonal antibody will work?

Asked by: Trav11
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support
Date published: 2017-03-06
  • y_2025, m_8, d_30, h_9CST
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Rated 5 out of 5 by from western以及IF效果很好western蛋白条带很清晰,没有杂带,组织荧光效果也很不错,特异性很好,Santa抗体购买很划算,强烈推荐。
Date published: 2017-12-19
Rated 5 out of 5 by from Good antibodyWestern blot works in HeLa whole cell lysates and we dilute the antibody with 1:500 get the right band.
Date published: 2017-10-28
Rated 5 out of 5 by from good for westernI failed to test IK1 protein in THP1, NB4 and HL60, but I can test them at RNA level
Date published: 2017-07-26
Rated 5 out of 5 by from high specity and affinityI got it 2 months ago, used it for several round. It gives me stable output
Date published: 2017-03-08
Rated 5 out of 5 by from RecommendedThis antibody gave strong signal of IK1 with minimal background in Western blot (WB). Recommended starting dilution of 1:800.
Date published: 2017-02-25
Rated 5 out of 5 by from Great antibody for WesternsThis antibody is well-cited for a variety of applications including WB, IP, IF, and even ELISA. Strong, clear signal with little to no background. Great in WB.
Date published: 2017-01-17
Rated 5 out of 5 by from perfect antibodyI used this antibody to decet IK1 in mouse brain,the blot is quite clear.
Date published: 2016-12-17
Rated 5 out of 5 by from Produced nice Western blot data of IK1 expressionProduced nice Western blot data of IK1 expression in HCT 116, HeLa and DU 145 whole cell lysates. -SCBT QC
Date published: 2013-07-05
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IK1 抗体 (D-5) is rated 5.0 out of 5 by 8.
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