Date published: 2025-9-8

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Ig κ light chain 抗体 (2G5-14): sc-69921

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说明书
  • Ig kappa light chain 抗体 2G5-14 是小鼠单克隆 IgG1Ig κ light chain抗体,规格为100 µg/ml
  • 免疫human物种的Ig κ light chain
  • 推荐用于 human 来源的Ig κ light chain WB, IP 和 ELISA检测; 不会与 Ig λ light chain产生交联反应
  • 关于如何获取Ig κ light chain (2G5-14): sc-69921免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前,我们还没有完成Ig κ light chain 抗体 (2G5-14)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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    抗 Ig κ 轻链抗体(2G5-14)是一种小鼠单克隆 IgG1 kappa 轻链抗体,可通过免疫印迹(WB)、免疫沉淀(IP)和酶联免疫吸附试验(ELISA)检测人源 Ig κ 轻链蛋白。抗 Ig κ 轻链抗体 (2G5-14) 以非结合形式提供,为研究人员提供了研究免疫系统中这一关键成分的可靠工具。Ig κ 轻链在形成免疫球蛋白方面起着至关重要的作用,而免疫球蛋白是适应性免疫反应所必需的。这些免疫球蛋白由两条完全相同的重链和两条完全相同的轻链组成,形成 Y 型结构,能够识别和结合抗原。Kappa 轻链的存在有助于 B 细胞产生多样化的抗体,从而有效应对各种病原体。编码κ轻链的基因位于 2 号染色体上,它们在 B 细胞发育过程中的重排产生了多样化的抗体库。了解 Ig κ 轻链的功能和意义有助于免疫学研究和针对免疫反应的治疗策略。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    Ig κ light chain 抗体 (2G5-14) 参考文献:

    1. 神秘的免疫球蛋白轻链  |  Pilström, L. 2002. Dev Comp Immunol. 26: 207-15. PMID: 11696386
    2. 异常人类宫颈上皮细胞中免疫球蛋白 kappa 轻链恒定区的表达。  |  Li, M., et al. 2004. Int J Biochem Cell Biol. 36: 2250-7. PMID: 15313470
    3. 针对人类白细胞抗原的单克隆抗体。I. 抗 beta-2-微球蛋白, 免疫球蛋白卡帕轻链, HLA-DR 样抗原, T8 抗原, T1 抗原, 一种单核细胞抗原和一种泛白细胞抗原的抗体。  |  Horejsí, V., et al. 1986. Folia Biol (Praha). 32: 12-25. PMID: 2422063
    4. 人类免疫球蛋白 kappa J 区基因的进化。  |  Hieter, PA., et al. 1982. J Biol Chem. 257: 1516-22. PMID: 6276389
    5. 小鼠产生λ轻链的B淋巴细胞中的新型卡帕轻链基因重排。  |  Durdik, J., et al. Nature. 307: 749-52. PMID: 6422305
    6. 大鼠混合淋巴细胞反应:树突状细胞在肠道淋巴中的作用以及由单克隆抗体定义的 T 细胞亚群。  |  Mason, DW., et al. 1981. Immunology. 44: 75-87. PMID: 6456222
    7. 克隆的人类和小鼠卡帕免疫球蛋白恒定区和 J 区基因在功能片段上保持同源性。  |  Hieter, PA., et al. 1980. Cell. 22: 197-207. PMID: 6775818
    8. 大鼠的固定 T 淋巴细胞干细胞。通过表面 W3/13 抗原和放射敏感性确定其特征。  |  Dyer, MJ. and Hunt, SV. 1981. J Exp Med. 154: 1164-77. PMID: 6974759

    订购信息

    产品名称产品编号规格价格数量收藏夹

    Ig κ light chain 抗体 (2G5-14)

    sc-69921
    100 µg/ml
    RMB2377.00

    Does this antibody recognize the CH1 or the variable region (VL) of the human kappa chain?

    Asked by: Alma123
    Thank you for your question. It would be helpful if you could call 800-457-3801, allowing for a more interactive discussion of this and other related questions.
    Answered by: Technical Service
    Date published: 2022-08-10

    For Western Blot, is it recommended to use denatured or non-denatured conditions with Ig κ light chain (2G5-14): sc-69921 antibody?

    Asked by: AbPolly
    Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
    Answered by: Technical Support
    Date published: 2017-03-27
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    Rated 5 out of 5 by from Good for Western BlotAntibody detects over-expressed human Ig κ light chain in transfected lysate sc-114846 and endogenous human Ig κ light chain in U-698-M cell lysate.. -SCBT QC
    Date published: 2023-09-14
    Rated 5 out of 5 by from Positive detection of endogenous human IgPositive detection of endogenous human Ig light chain protein in U-698-M whole cell lysate.
    Date published: 2015-03-11
    Rated 5 out of 5 by from Good specificity shown by using transfectedGood specificity shown by using transfected and non-transfected 293T cells for over-expression of the human Ig light chain protein via Western Blot analysis. -SCBT QC
    Date published: 2014-02-11
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    Ig κ light chain 抗体 (2G5-14) is rated 5.0 out of 5 by 3.
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