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HSV-1 ICP4 Immediate Early Protein 抗体 (10F1): sc-56986

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说明书
  • HSV-1 ICP4 Immediate Early Protein 抗体 10F1 是小鼠单克隆 IgG1，HSV-1 ICP4 Immediate Early Protein抗体, 在15篇文献中引用，规格为100 µg/ml
  • 针对herpes simplex virus type 1
  • 推荐用于 HSV-1 来源的ICP4 Immediate Early Protein WB 和 IF检测
  • 关于如何获取HSV-1 ICP4 Immediate Early Protein (10F1): sc-56986的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP是HSV-1 ICP4 Immediate Early Protein Antibody (10F1) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与HSV-1 ICP4 Immediate Early Protein Antibody (10F1) 搭配使用（请参阅下面的订购信息）。

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関連項目

附加HSV Protein抗体，包括HSV-1 gD, HSV-1, HSV-1 Envelope Protein, HSV-1 gB, HSV-1 gC, HSV-1 gC Envelope Protein, HSV-1 gE, HSV-1 gE Envelope Protein, HSV-1 gG, HSV-1 gG Envelope Protein, HSV-1 Glycoprotein B, HSV-1 ICP0, HSV-1 ICP27, HSV-1 ICP35, HSV-1 ICP4和HSV-1 ICP4 Immediate Early Protein

HSV-1 ICP4立即早期蛋白抗体（10F1）是一种IgG1小鼠单克隆HSV-1 ICP4立即早期蛋白抗体（也称为HSV-1 ICP4立即早期蛋白抗体），可通过WB和IF检测HSV-1来源的HSV-1 ICP4立即早期蛋白。HSV-1 ICP4立即早期蛋白抗体（10F1）可作为非偶联抗HSV-1 ICP4立即早期蛋白抗体使用。单纯疱疹病毒1型（HSV-1）的感染细胞多肽4（ICP4）是感染后立即产生的五种立即早期转录调控蛋白之一。ICP4对于早期和晚期病毒基因的充分转录是必需的。ICP4立即早期蛋白是病毒生长所必需的，它通过激活基因表达在病毒感染期间放大病毒基因的转录速率。ICP4立即早期蛋白还在重构的转录反应中启动转录。通过增加或减少由RNA聚合酶II介导的转录起始复合物的形成速率，转录通过一组通用转录因子（GTFs）被激活。ICP4立即早期蛋白通过增加TFIID与TATA盒的结合，特异性地促进转录PIC（预起始复合物）的形成。数据表明，在感染过程中，ICP4蛋白在指导HSV-1基因组的无尽环状构象方面也起着关键作用。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

HSV-1 ICP4 Immediate Early Protein 抗体 (10F1) 参考文献:

  1. 单纯疱疹病毒 1 型 ICP4 通过增强 TFIID 与 DNA 的结合促进转录前启动复合物的形成。  |  Grondin, B. and DeLuca, N. 2000. J Virol. 74: 11504-10. PMID: 11090147
  2. 病毒生命中的前 30 分钟：在细胞核中不安宁。  |  Roizman, B., et al. 2005. Cell Cycle. 4: 1019-21. PMID: 16082207
  3. ICP27 依赖性 1 型单纯疱疹病毒对 Leptomycin B 的抗性与 ICP4 和 ICP0 的核定域增强缔合作用有关。  |  Lengyel, J., et al. 2006. Virology. 352: 368-79. PMID: 16780914
  4. 有证据表明，1 型单纯疱疹病毒 ICP4 基因缺失突变株 d120 的基因组在感染细胞中循环所必需的即时早期基因产物 ICP4。  |  Su, YH., et al. 2006. J Virol. 80: 11589-97. PMID: 16987974
  5. 特立尼达同性恋男子中 HTLV-I 和艾滋病毒的传播。  |  Bartholomew, C., et al. 1987. JAMA. 257: 2604-8. PMID: 2883330
  6. 单纯疱疹病毒 ICP4 通过与基础转录因子 TATA 结合蛋白和 TFIIB 的相互作用机制抑制激活因子介导的转录。  |  Gu, B., et al. 1995. Mol Cell Biol. 15: 3618-26. PMID: 7791769
  7. ICP4 是 1 型单纯疱疹病毒的主要转录调控蛋白，与 TATA 结合蛋白和 TFIIB 形成三方复合物。  |  Smith, CA., et al. 1993. J Virol. 67: 4676-87. PMID: 8392607

订购信息

产品名称产品编号规格价格数量收藏夹

HSV-1 ICP4 Immediate Early Protein 抗体 (10F1)

sc-56986
100 µg/ml
RMB2377.00

HSV-1 ICP4 Immediate Early Protein (10F1): m-IgG Fc BP-HRP 套装

sc-539046
100 µg Ab; 10 µg BP
RMB2662.00

Will this antibody recognize HSV-2 as well?

Asked by: angry virome
Thank you for your question. We do not have any references or data indicating that this antibody would also recognize HSV-2.
Answered by: Technical Support
Date published: 2019-05-07

What is the total volume provided of HSV-1 ICP4 Immediate Early Protein (10F1): sc-56986 monoclonal antibody?

Asked by: Professor Griffin
Thank you for your question. This antibody is provided as 100 µg in 1 ml total volume.
Answered by: Technical Support
Date published: 2017-03-07
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Rated 5 out of 5 by from Good choice for immunofluorescenceAntibody has been used for Immunofluorescence in published research. -SCBT QC
Date published: 2023-09-14
Rated 4 out of 5 by from Produced publishable WB data with human samplesProduced publishable WB data with human samples - SCBT Publication Review
Date published: 2015-03-20
Rated 4 out of 5 by from Working very wellWorking very well.
Date published: 2015-03-19
Rated 4 out of 5 by from Antibody used for IHC (pfa) with porcine neuronsAntibody used for IHC (pfa) with porcine neurons - SCBT Publication Review
Date published: 2015-02-09
Rated 4 out of 5 by from Used in IF with Virus infected CellsUsed in IF with Virus infected Cells - SCBT Publication Review
Date published: 2015-02-02
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HSV-1 ICP4 Immediate Early Protein 抗体 (10F1) is rated 4.2 out of 5 by 5.
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