Date published: 2025-9-10

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HoxB13 抗体 (F-9): sc-28333

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说明书
  • HoxB13 抗体 F-9 是小鼠单克隆 IgG1 κ,HoxB13抗体, 在40篇文献中引用,规格为200 µg/ml
  • 免疫human物种的HoxB13的氨基酸1-284
  • HoxB13 抗体 (F-9) 推荐用于WB, IP, IF, IHC(P) 和 ELISA,检测human 来源的 HoxB13
  • 抗HoxB13抗体(F-9)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 可用于凝胶迁移和ChIP的TransCruz试剂(sc-28333 X, 200 µg/0.1 ml)
  • 关于如何获取HoxB13 (F-9): sc-28333免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgGκ BP-HRP 是 HoxB13 抗体 (F-9) 在 WB and IHC(P) 应用中的首选二抗检测试剂。该试剂现与HoxB13 抗体 (F-9) 组合成套装提供。 (请参阅下面的订购信息)。其他m-IgGκ BP 偶联产品,请参阅我们的小鼠 IgG 结合蛋白完整列表。

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関連項目

HoxB13抗体(F-9)是一种小鼠单克隆IgG1 kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)、石蜡包埋切片免疫组织化学(IHCP)和酶联免疫吸附测定(ELISA)检测人类HoxB13蛋白。(ELISA)。抗HoxB13抗体(F-9)有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和多种Alexa Fluor®结合物。HoxB13蛋白在Hox基因家族中作为序列特异性转录因子发挥着关键作用,对于脊椎动物各种结构的正常发育至关重要,包括中枢神经系统、四肢和泌尿生殖道。HoxB13主要表达于前列腺,对于正常分化与分泌功能至关重要,这凸显了HoxB13在前列腺健康与疾病中的重要性。HoxB13蛋白主要定位于细胞核,负责调节基因表达,但在胎儿皮肤发育和某些皮肤增生性疾病中,HoxB13也会定位于细胞质,这表明HoxB13在细胞过程中发挥着动态作用。HoxB13 单克隆抗体(F-9)是研究发育生物学、前列腺癌及相关领域研究人员的宝贵工具,有助于深入了解这些关键生物学过程的分子机制。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

HoxB13 抗体 (F-9) 参考文献:

  1. 腹侧前列腺的正常分化和分泌功能需要 Hoxb13。  |  Economides, KD. and Capecchi, MR. 2003. Development. 130: 2061-9. PMID: 12668621
  2. HOXB13 同源域蛋白在整个胎儿皮肤发育过程中都处于细胞质中。  |  Kömüves, LG., et al. 2003. Dev Dyn. 227: 192-202. PMID: 12761847
  3. HOXB13 同源结构域蛋白通过负向调节 T 细胞因子 4 抑制前列腺癌细胞的生长。  |  Jung, C., et al. 2004. Cancer Res. 64: 3046-51. PMID: 15126340
  4. 两个基因的表达比值可预测接受他莫昔芬治疗的乳腺癌患者的临床结果。  |  Ma, XJ., et al. 2004. Cancer Cell. 5: 607-16. PMID: 15193263
  5. 人类前列腺组织的分子图谱分析:对青春期前列腺发育基因表达模式的见解。  |  Dhanasekaran, SM., et al. 2005. FASEB J. 19: 243-5. PMID: 15548588
  6. HOXB13 作为激素激活的雄激素受体信号传导的抑制因子,可诱导前列腺癌细胞的生长抑制。  |  Jung, C., et al. 2004. Cancer Res. 64: 9185-92. PMID: 15604291
  7. 由赤曲霉引起的过敏性支气管肺曲霉病,表现为肺叶塌陷。  |  Nakahara, Y., et al. 1992. Intern Med. 31: 140-2. PMID: 1568035
  8. 人子宫内膜癌中过量表达的 HOXB13 基因对肿瘤侵袭的调控。  |  Zhao, Y., et al. 2005. Oncol Rep. 13: 721-6. PMID: 15756448
  9. Hoxb-13:HOXB 群遥远区域的新 Hox 基因保持共线性。  |  Zeltser, L., et al. 1996. Development. 122: 2475-84. PMID: 8756292
  10. 无疤痕胎儿伤口中人类同源基因 PRX-2 和 HOXB13 的调控。  |  Stelnicki, EJ., et al. 1998. J Invest Dermatol. 111: 57-63. PMID: 9665387

订购信息

产品名称产品编号规格价格数量收藏夹

HoxB13 抗体 (F-9)

sc-28333
200 µg/ml
RMB2377.00

HoxB13 (F-9): m-IgGκ BP-HRP 套装

sc-520802
200 µg Ab, 40 µg BP
RMB2662.00

HoxB13 抗体 (F-9) X

sc-28333 X
200 µg/0.1 ml
RMB2377.00

HoxB13 抗体 (F-9) AC

sc-28333 AC
500 µg/ml, 25% agarose
RMB3129.00

HoxB13 抗体 (F-9) HRP

sc-28333 HRP
200 µg/ml
RMB2377.00

HoxB13 抗体 (F-9) FITC

sc-28333 FITC
200 µg/ml
RMB2482.00

HoxB13 抗体 (F-9) PE

sc-28333 PE
200 µg/ml
RMB2580.00

HoxB13 抗体 (F-9) Alexa Fluor® 488

sc-28333 AF488
200 µg/ml
RMB2685.00

HoxB13 抗体 (F-9) Alexa Fluor® 546

sc-28333 AF546
200 µg/ml
RMB2685.00

HoxB13 抗体 (F-9) Alexa Fluor® 594

sc-28333 AF594
200 µg/ml
RMB2685.00

HoxB13 抗体 (F-9) Alexa Fluor® 647

sc-28333 AF647
200 µg/ml
RMB2685.00

HoxB13 抗体 (F-9) Alexa Fluor® 680

sc-28333 AF680
200 µg/ml
RMB2685.00

HoxB13 抗体 (F-9) Alexa Fluor® 790

sc-28333 AF790
200 µg/ml
RMB2685.00

What do you suggest I use for visualizing my Western blot?

Asked by: Cweed
We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support 7
Date published: 2017-01-13

I want to use sc-28333 for IHC in my mouse samples. How can I do it with a mouse monoclonal?

Asked by: Cweed
We recommend using a directly conjugated primary antibodies. This product, sc-28333, is available conjugated to FITC, AF488, and AF647.
Answered by: Technical Support 7
Date published: 2018-09-27
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Rated 5 out of 5 by from Good for Co-immunoprecipitationI bought it for my CoIP assay in LNCaP cells. It worked nicely and gave me a really good shape band.
Date published: 2017-04-18
Rated 5 out of 5 by from Simply outstanding !!Superb IHC staining data;strong signal with low background; also great western
Date published: 2017-01-20
Rated 5 out of 5 by from great staining resultsThis HoxB13 antibody shows great results for staining in IHC and IF.
Date published: 2017-01-12
Rated 5 out of 5 by from This is a great WB antibodyThis is a great WB antibody, we use it routinely and works great.
Date published: 2015-09-22
Rated 5 out of 5 by from StrongStrong, clean band present in WB analysis in LNCaP whole cell lysate. -SCBT QC
Date published: 2015-05-18
Rated 5 out of 5 by from Produced excellent immunoperoxidase nuclearProduced excellent immunoperoxidase nuclear staining in formalin fixed, paraffin-embedded human rectum tissue. -SCBT QC
Date published: 2015-05-05
Rated 5 out of 5 by from Paraffin embedded human phyllodes tumor sectionsParaffin embedded human phyllodes tumor sections were stained with the HOXB13 antibody at a 1:20 dilution. -SCBT Publication Review
Date published: 2015-05-05
Rated 5 out of 5 by from Published immunohistochemical analysis ofPublished immunohistochemical analysis of human MEPNs using a 1:200 dilution. -SCBT Publication Review
Date published: 2015-04-16
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HoxB13 抗体 (F-9) is rated 5.0 out of 5 by 9.
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