Date published: 2025-9-6

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hnRNP L 抗体 (4D11): sc-32317

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说明书
  • hnRNP L 抗体 4D11 是小鼠单克隆 IgG1 κ,hnRNP L抗体, 在51篇文献中引用,规格为200 µg/ml
  • 针对humanhnRNP蛋白(来自HeLa细胞)通过亲和层析法纯化,在ssDNA琼脂糖上
  • hnRNP L 抗体 (4D11) 推荐用于 WB, IP, IF 和 IHC(P),检测mouse, rat 和human 来源的 hnRNP L
  • 抗hnRNP L抗体(4D11)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取hnRNP L (4D11): sc-32317免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRPm-IgGκ BP-HRP 是 hnRNP L 抗体 (4D11) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与hnRNP L 抗体 (4D11) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

hnRNP L 抗体(4D11)是一种小鼠单克隆 IgG1 kappa 轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和免疫组织化学检测小鼠、大鼠和人类来源的 hnRNP L 蛋白。抗 hnRN P L抗体(4D11)有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和多种Alexa Fluor®结合物。异质核糖核蛋白L(hnRNP L)在调节基因表达方面发挥着至关重要的作用,特别是在mRNA转录、前mRNA处理以及将成熟mRNA转运至细胞质进行翻译方面。hnRNP L主要位于核质中,与RNA和其他蛋白质相互作用,影响可变剪接机制,这对于产生蛋白质多样性和调节细胞反应至关重要。hnRNP L与hnRN P I同源物结合到内含子的3'端,从而调节可影响各种基因表达的剪接事件,包括与丙型肝炎病毒(HCV)等病毒感染相关的基因。hnRNP L能够在细胞核和细胞质之间穿梭,这进一步凸显了其在转录后调控中的重要性,使其成为基因表达和病毒发病机理相关研究的重要靶标。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

hnRNP L 抗体 (4D11) 参考文献:

  1. 核前 mRNA 区隔:将释放的转录本运送到剪接因子库。  |  Melcák, I., et al. 2000. Mol Biol Cell. 11: 497-510. PMID: 10679009
  2. 在细胞核和细胞质之间穿梭的 hnRNPs 之间的蛋白质相互作用。  |  Kim, JH., et al. 2000. J Mol Biol. 298: 395-405. PMID: 10772858
  3. 编码异质核核糖核蛋白 I 型(hnRNP I)的人类基因的组织和 hnRNP I 相关假基因的特征。  |  Romanelli, MG., et al. 2000. Gene. 255: 267-72. PMID: 11024286
  4. hnRNP A1 蛋白的核定位结构域。  |  Siomi, H. and Dreyfuss, G. 1995. J Cell Biol. 129: 551-60. PMID: 7730395
  5. 新型人类 RNA 结合蛋白的鉴定和特性分析。  |  Badolato, J., et al. 1995. Gene. 166: 323-7. PMID: 8543184
  6. 多个 RRM 有助于提高 RNA 结合的特异性和多嘧啶束结合蛋白的亲和力。  |  Pérez, I., et al. 1997. Biochemistry. 36: 11881-90. PMID: 9305981
  7. 多嘧啶束结合蛋白与 HnRNP L 相互作用  |  Hahm, B., et al. 1998. FEBS Lett. 425: 401-6. PMID: 9563502
  8. 异质核糖核蛋白 L 与丙型肝炎病毒内部核糖体入口位点的 3' 边界相互作用。  |  Hahm, B., et al. 1998. J Virol. 72: 8782-8. PMID: 9765422
  9. 多嘧啶束结合蛋白与小鼠肝炎病毒的领导 RNA 结合,是病毒转录的调节因子。  |  Li, HP., et al. 1999. J Virol. 73: 772-7. PMID: 9847386

订购信息

产品名称产品编号规格价格数量收藏夹

hnRNP L 抗体 (4D11)

sc-32317
200 µg/ml
RMB2377.00

hnRNP L (4D11): m-IgG Fc BP-HRP 套装

sc-528461
200 µg Ab; 10 µg BP
RMB2662.00

hnRNP L (4D11): m-IgGκ BP-HRP 套装

sc-520844
200 µg Ab, 40 µg BP
RMB2662.00

hnRNP L (4D11): m-IgG1 BP-HRP 套装

sc-542941
200 µg Ab; 20 µg BP
RMB2662.00

hnRNP L 抗体 (4D11) AC

sc-32317 AC
500 µg/ml, 25% agarose
RMB3129.00

hnRNP L 抗体 (4D11) HRP

sc-32317 HRP
200 µg/ml
RMB2377.00

hnRNP L 抗体 (4D11) FITC

sc-32317 FITC
200 µg/ml
RMB2482.00

hnRNP L 抗体 (4D11) PE

sc-32317 PE
200 µg/ml
RMB2580.00

hnRNP L 抗体 (4D11) Alexa Fluor® 488

sc-32317 AF488
200 µg/ml
RMB2685.00

hnRNP L 抗体 (4D11) Alexa Fluor® 546

sc-32317 AF546
200 µg/ml
RMB2685.00

hnRNP L 抗体 (4D11) Alexa Fluor® 594

sc-32317 AF594
200 µg/ml
RMB2685.00

hnRNP L 抗体 (4D11) Alexa Fluor® 647

sc-32317 AF647
200 µg/ml
RMB2685.00

hnRNP L 抗体 (4D11) Alexa Fluor® 680

sc-32317 AF680
200 µg/ml
RMB2685.00

hnRNP L 抗体 (4D11) Alexa Fluor® 790

sc-32317 AF790
200 µg/ml
RMB2685.00

I need to use an antibody to detect the protein in samples of equine origin. Do you know if this mouse monoclonal antibody will work?

Asked by: jerojero
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support 15
Date published: 2017-01-25
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Rated 5 out of 5 by from Strong bands for WBWorked well for nuclear extract western blots. Strong bands were detected for hnRNPL.
Date published: 2017-07-05
Rated 5 out of 5 by from Great antibody!Highly recommended for IHC on paraffin sections, as well as IF on fresh frozen tissues, specific and strong staining seen in both. Also gives nice single bands in WB experiments.
Date published: 2017-01-09
Rated 5 out of 5 by from work well in WB and IPwork well in WB(1:1000) and Immunoprecipitation in 293T cell
Date published: 2016-11-11
Rated 5 out of 5 by from Published data for IP and WB in human HEKPublished data for IP and WB in human HEK 293T cell line. -SCBT Publication Review
Date published: 2015-03-31
Rated 5 out of 5 by from Strong signal in WB in HeLa and SHPStrong signal in WB in HeLa and SHP-77 whole cell lysates and MEG-01 , Jurkat, HeLa and RAW 264.7 nuclear extracts. -SCBT QC
Date published: 2015-03-08
Rated 5 out of 5 by from Robust signal in WB in Sol8Robust signal in WB in Sol8, Jurkat and HeLa nuclear extracts. -SCBT QC
Date published: 2015-02-21
Rated 5 out of 5 by from Published data for WB and EMSA in human MCFPublished data for WB and EMSA in human MCF-7 human breast carcinoma cells. -SCBT Publication Review
Date published: 2015-02-12
Rated 5 out of 5 by from Produced great immunoperoxidase nuclear stainingProduced great immunoperoxidase nuclear staining in formalin fixed, paraffin-embedded human ovary tissue. -SCBT QC
Date published: 2015-02-03
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hnRNP L 抗体 (4D11) is rated 4.9 out of 5 by 10.
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