Date published: 2025-9-6

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HLA-C 抗体 (H-5): sc-166134

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说明书
  • HLA-C抗体(H-5)是小鼠单克隆IgG3 κ, 在1篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的HLA-C的内部区域内的氨基酸91-123之间
  • 推荐用于 human 来源的HLA-C WB, IP, IF, IHC(P) 和 ELISA检测
  • 看 MHC class I (W6/32): sc-32235,可查看有标记的 HLA-C 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 关于如何获取HLA-C (H-5): sc-166134免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG3 BP-HRPm-IgGκ BP-HRP是HLA-C抗体(H-5)在WB and IHC(P)应用中的首选二次检测试剂。这些试剂现在与HLA-C 抗体(H-5)捆绑销售(见下文订购信息)。

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関連項目

HLA-C抗体(H-5)是一种IgG3 κ小鼠单克隆HLA-C抗体(也称为HLA-C抗体或HLAC抗体),可通过WB、IP、IF、IHC(P)和ELISA检测人源HLA-C。HLA-C抗体(H-5)为非偶联抗HLA-C抗体形式。主要组织相容性复合体(MHC)II类分子向CD4+辅助T细胞的呈递由两个关键事件决定。这些事件包括通过MHC分子HLA-DM和-DO的活性,从MHC IIa/b二聚体的抗原结合凹槽中解离与II类相关的恒定链肽(CLIP),以及随后的肽抗原结合。HLA-DM、-DO分子在内体/溶酶体区室和B细胞表面积累,通过维持有利于肽交换的构象,调节CLIP的解离以及随后外源性肽与HLA II类分子(HLA-DR、-DQ和-DP)的结合。对类风湿性关节炎(RA)患者HLA-DM基因的RFLP分析表明,某些多态性是RA易感性的遗传因素。HLA-B属于HLA I类重链旁系同源物。I类分子在免疫系统中通过呈递来自内质网腔的肽发挥核心作用。HLA-B和-C可以形成由膜锚定重链和轻链(β-2-微球蛋白)组成的异二聚体。多态性产生数百个HLA-B和-C等位基因。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

HLA-C 抗体 (H-5)

sc-166134
200 µg/ml
RMB2377.00

HLA-C (H-5): m-IgGκ BP-HRP 套装

sc-521519
200 µg Ab, 40 µg BP
RMB2662.00

HLA-C (H-5): m-IgG3 BP-HRP 套装

sc-551262
200 µg Ab; 40 µg BP
RMB2662.00

HLA-C (H-5) 中和勝肽

sc-166134 P
100 µg/0.5 ml
RMB511.00

What application is the blocking peptide sc-166134 P appropriate for?

Asked by: AbPolly
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
  • y_2025, m_8, d_30, h_9CST
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Rated 1 out of 5 by from Tested on HFFF by FACSThis antibody was tested on HFFF cells by FACS and did not give a signal, even at dilution 1:25
Date published: 2018-11-19
Rated 5 out of 5 by from Good stainingNo problem on human brain IHC, pH 9 demasking, 1:50 dilution.
Date published: 2017-11-08
Rated 5 out of 5 by from Great monoclonal for HLA-CStrong and specific, this is a very reliable antibody for both IHC and WB. Smart choice!
Date published: 2017-02-07
Rated 5 out of 5 by from Produced excellent immunoperoxidase cytoplasmicProduced excellent immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human cervix tissue. -SCBT QC
Date published: 2015-05-02
Rated 5 out of 5 by from Strong band seen in WB in CCRFStrong band seen in WB in CCRF-HSB-2 whole cell lysate. -SCBT QC
Date published: 2015-04-06
Rated 5 out of 5 by from Good antibody for WB in nonGood antibody for WB in non-transfected 293, human HLA-C transfected 293 and HeLa whole cell lysates. -SCBT QC
Date published: 2015-01-09
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HLA-C 抗体 (H-5) is rated 4.3 out of 5 by 6.
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