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GSTP1 抗体 (F-6): sc-376481

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说明书
  • GSTP1抗体(F-6)是小鼠单克隆IgG2a κ, 在4篇文献中引用,规格为200 µg/ml
  • 与氨基酸1-210结合,代表全长谷胱甘肽S-转移酶Pi,源自human
  • 推荐用于 human 来源的GSTP1 WB, IP, IF 和 ELISA检测
  • m-IgG Fc BP-HRP和 2a BP-HRP">m-IgG2a BP-HRP是GSTP1 Antibody (F-6) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与GSTP1 Antibody (F-6) 打包提供(请参阅下面的订购信息)。
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関連項目

谷胱甘肽S-转移酶(GSTs)在各种环境致癌物和脂质氢过氧化物的代谢解毒中发挥作用。在对氧化应激的反应中,GST家族成员GSTP1发生上调,这与该功能一致。此外,GSTP1基因经历CpG岛超甲基化,这种状态与人类前列腺癌发生有关。GSTP1基因高甲基化可以在患有前列腺癌症的男性的尿液、精液和血浆中检测到,这可能使GSTP1成为前列腺癌症筛查的有用生物标志物。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

GSTP1 抗体 (F-6) 参考文献:

  1. 用普鲁卡因胺治疗可逆转GSTP1 CpG岛高甲基化,并重新激活人前列腺癌细胞中pi类谷胱甘肽S-转移酶(GSTP1)的表达。  |  Lin, X., et al. 2001. Cancer Res. 61: 8611-6. PMID: 11751372
  2. GSTM1、GSTT1和GSTP1基因型以及氢醌对人类淋巴细胞的遗传毒性。  |  Silva, Mdo C., et al. 2004. Environ Mol Mutagen. 43: 258-64. PMID: 15141365
  3. 谷胱甘肽S-转移酶(GSTP1)Pi异构体的鉴定和表征,作为人眼黄斑中的玉米黄质结合蛋白。  |  Bhosale, P., et al. 2004. J Biol Chem. 279: 49447-54. PMID: 15355982
  4. 候选膳食植物化学物质可调节人体肺细胞中II期酶GSTP1和NQO1的表达。  |  Tan, XL., et al. 2010. J Nutr. 140: 1404-10. PMID: 20554899
  5. GSTP1表达可预测ER阴性乳腺癌对新辅助化疗的不良病理完全反应。  |  Miyake, T., et al. 2012. Cancer Sci. 103: 913-20. PMID: 22320227
  6. miR-513a-3p 通过靶向 GSTP1 使人类肺腺癌细胞对化疗敏感。  |  Zhang, X., et al. 2012. Lung Cancer. 77: 488-94. PMID: 22749944
  7. 单剂量GSTP1可预防梗塞引发的心力衰竭。  |  Andrukhova, O., et al. 2014. J Card Fail. 20: 135-45. PMID: 24412522
  8. 乳腺癌中的CYP1A1和GSTP1基因变异:系统回顾和病例对照研究。  |  Akhtar, S., et al. 2016. Fam Cancer. 15: 201-14. PMID: 26545608
  9. GSTP1 rs1695多态性与哮喘发病和表型表现的关系分析。  |  Mukhammadiyeva, GF., et al. 2022. J Asthma. 59: 1065-1069. PMID: 33781157
  10. GSTP1-rs1695多态性与口腔癌风险的相关性分析:文献综述、更新荟萃分析和结构评估。  |  Baghaei, A., et al. 2022. Asian Pac J Cancer Prev. 23: 3859-3868. PMID: 36444599

订购信息

产品名称产品编号规格价格数量收藏夹

GSTP1 抗体 (F-6)

sc-376481
200 µg/ml
CNY2422.00

GSTP1 (F-6): m-IgG Fc BP-HRP 套装

sc-540582
200 µg Ab; 10 µg BP
CNY2715.00

GSTP1 (F-6): m-IgG2a BP-HRP 套装

sc-546930
200 µg Ab; 10 µg BP
CNY2715.00

Is it suitable for WB in rabbits?

Asked by: salah
Thank you for your question. GSTP1 Antibody (F-6): sc-376481 is only recommended for detection of GSTP1 of human origin by WB, IP, IF and ELISA. Our tests with this antibody indicate that it does not produce reliable results when used in other assays or species. Please contact our technical service if you require further information.
Answered by: SCBT Heidelberg Support
Date published: 2019-01-06

Does GSTP 1/2  SC-376481 can detect a GST protein  from a rabbit origin by western blot

Asked by: Reem Bakir
Thank you for your question. This mouse monoclonal antibody, GSTP1 (F-6): sc-376481, is recommended for detection of GSTP1 (Glutathione S-transferase Pi) of human origin. We have not tested the antibody in rabbit samples and do not know if it would work for this species. Please contact our Technical Service Department if you would like us to perform sequence analysis against the rabbit protein to predict whether or not the antibody may be able to cross-react with the rabbit protein.
Answered by: Technical Support
Date published: 2017-12-07

What is the recommended fixation method for immunofluorescence staining with GSTP1 (F-6): sc-376481 monoclonal antibody?

Asked by: TinTin
Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10°C methanol and allowing to air dry. The full protocol can be viewed here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by LR from WB publishable data with human HLWB publishable data with human HL-60 - SCBT Publication Review
Date published: 2015-01-02
Rated 5 out of 5 by NZ from Beautiful immunofluorescence nuclear andBeautiful immunofluorescence nuclear and cytoplasmic staining in methanol-fixed HeLa cells. -SCBT QC
Date published: 2013-07-29
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GSTP1 抗体 (F-6) is rated 5.0 out of 5 by 2.
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