Date published: 2025-9-7
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GSK3 beta Antibody (11B9) - Western Blotting - Image 54858
GSK-3β (11B9): sc-81462. 对 A-431 全细胞裂解液中 GSK-3β 的表达进行 Western 印迹分析.
GSK-3β (11B9): sc-81462. 对 A-431 全细胞裂解液中 GSK-3β 的表达进行 Western 印迹分析.

GSK3 beta 抗体 (11B9): sc-81462

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说明书
  • GSK3 beta 抗体 11B9 是小鼠单克隆 IgG1, 在83篇文献中引用，提供 50 µg/0.5 ml
  • 针对GSK-3β的human起源的N-terminus的
  • 推荐用于 mouse, rat 和 human 来源的GSK-3β WB 和 IP检测; 也和以下物种反应，包括： canine
  • 看 GSK3 alpha/beta (0011-A): sc-7291，可查看有标记的 GSK3 beta 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 关于如何获取GSK3 beta (11B9): sc-81462的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP和 1 BP-HRP">m-IgG1 BP-HRP是GSK3 beta Antibody (11B9) for WB applications. 的首选辅助检测试剂，这些试剂现与GSK3 beta Antibody (11B9) 打包提供（请参阅下面的订购信息）。

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描述
基因信息
说明书与实验方案
研究信息

関連項目

附加GSK抗体，包括GSK-3 α和GSK-3 β

GSK-3β抗体（11B9）是一种小鼠单克隆IgG1，可通过蛋白质印迹（WB）和免疫沉淀（IP）特异性检测小鼠、大鼠、人类和其他物种（包括犬）的糖原合酶激酶3β（GSK-3β）。GSK-3β是一种丝氨酸/苏氨酸激酶，在调节多种细胞过程（包括糖原代谢、细胞增殖和细胞凋亡）中发挥着关键作用。GSK-3β调节的一个关键方面是其翻译后修饰，特别是磷酸化。特定丝氨酸和酪氨酸残基的磷酸化可调节GSK-3β的活性，例如，Ser9的磷酸化可抑制其激酶活性，而Tyr216的磷酸化可增强其活性。这些修饰对于控制GSK-3β与底物的相互作用以及参与信号通路至关重要。GSK-3β翻译后修饰的失调与多种疾病有关，包括阿尔茨海默氏症等神经退行性疾病，其中GSK-3β靶标（如Tau蛋白）的异常磷酸化会导致病理状况。了解翻译后修饰如何影响GSK-3β的功能对于深入了解调节机制及其在疾病中的潜在作用至关重要，这使得抗GSK-3β抗体（11B9）成为研究人员在不同生物学背景下研究GSK-3β的宝贵工具。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

GSK3 beta 抗体 (11B9)

sc-81462
50 µg/0.5 ml
RMB2377.00

GSK3 beta (11B9): m-IgG Fc BP-HRP 套装

sc-539613
50 µg Ab; 10 µg BP
RMB2662.00

GSK3 beta (11B9): m-IgG1 BP-HRP 套装

sc-541600
50 µg Ab; 20 µg BP
RMB2662.00

What is the recommended dilution to use GSK-3β (11B9): sc-81462 monoclonal antibody in Western blot?

Asked by: cjMara
We recommend using GSK-3β (11B9): sc-81462 monoclonal antibody at a starting dilution of 1:200 (range 1:100-1:1,000) for Western blotting.
Answered by: Technical Support 9
Date published: 2017-01-26
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Rated 5 out of 5 by from Strong stainingThis antibody has a very strong signal used at 1:1000 dilution for western blot. Already tested in both differentiated SHSY-5Y and mice brain tissue samples
Date published: 2022-12-21
Rated 5 out of 5 by from Nice antibodySpecific for gsk3 beta at 1:500. May be even good to use at 1:1000 but we just never tried. This cell line is HEK293.
Date published: 2018-11-28
Rated 5 out of 5 by from strong signalStrong signal observed by WB with GSK-3 beta Antibody (11B9)
Date published: 2017-01-24
Rated 4 out of 5 by from Published data for WB in mouse R390A cPublished data for WB in mouse R390A c-src and D338N c-src cell lines. -SCBT Publication Review
Date published: 2015-05-19
Rated 4 out of 5 by from Worked well in WB in human GSKWorked well in WB in human GSK-3 transfected 293T whole cell lysate. -SCBT QC
Date published: 2015-05-18
Rated 4 out of 5 by from Published data for IP and WB in mouse kidneyPublished data for IP and WB in mouse kidney proximal tubular epithelial cells. -SCBT Publication Review
Date published: 2015-04-04
Rated 4 out of 5 by from Published data for WB in rat brainPublished data for WB in rat brain. -SCBT Publication Review
Date published: 2015-01-10
Rated 4 out of 5 by from Clear band in WB in mouse GSKClear band in WB in mouse GSK-3 transfected 293T and HeLa whole cell lysates. -SCBT QC
Date published: 2014-02-20
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GSK3 beta 抗体 (11B9) is rated 4.4 out of 5 by 8.
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