Date published: 2025-9-9

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GR/NR3C1/Glucocorticoid Receptor 抗体 (FiGR): sc-12763

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说明书
  • GR/NR3C1/Glucocorticoid Receptor抗体(FiGR)是小鼠单克隆IgG2b κ, 在21篇文献中引用,规格为200 µg/ml
  • 免疫mouse物种的GR α的氨基酸395-411
  • 抗-GR/NR3C1/Glucocorticoid Receptor 抗体 (FiGR) 推荐用于 WB 和 IP,检测mouse, rat 和human 来源的 GR α and GR β
  • 抗GR/NR3C1/Glucocorticoid Receptor抗体(FiGR)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 可用于凝胶迁移和ChIP的TransCruz试剂(sc-12763 X, 200 µg/0.1 ml)
  • 关于如何获取GR/NR3C1/Glucocorticoid Receptor (FiGR): sc-12763免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 2b BP-HRP">m-IgG2b BP-HRPm-IgGκ BP-HRP是GR/NR3C1/Glucocorticoid Receptor Antibody (FiGR) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与GR/NR3C1/Glucocorticoid Receptor Antibody (FiGR) 打包提供(请参阅下面的订购信息)。

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関連項目

GR抗体(FiGR)是一种小鼠单克隆IgG2b kappa轻链抗体,可通过蛋白质印迹(WB)和免疫沉淀(IP)检测小鼠、大鼠和人类来源的糖皮质激素受体(GR)蛋白。GR单克隆抗体(FiGR)有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶、藻红蛋白、异硫氰酸荧光素和多种Alexa Fluor®结合物。糖皮质激素受体是一种重要的转录因子,在调节糖皮质激素的生理效应方面发挥着至关重要的作用。糖皮质激素是类固醇激素,参与新陈代谢、免疫反应和应激调节等众多生物过程。糖皮质激素受体有两种主要的同工型,其中以α型最为常见,功能也最为重要。α型糖皮质激素受体在细胞质中处于非活性状态,直到与糖皮质激素结合,然后进入细胞核。GRα与细胞核中的特定DNA序列结合,调节细胞凋亡、细胞生长和分化等过程中必不可少的靶基因的转录。GR与各种协同调节因子和转录因子相互作用,包括AP-1复合物,后者对于调节激素信号引起的基因表达至关重要。了解GR的功能和动态对于阐明其在健康和疾病中的作用至关重要,特别是在与炎症、代谢紊乱和癌症相关的疾病中。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

订购信息

产品名称产品编号规格价格数量收藏夹

GR/NR3C1/Glucocorticoid Receptor 抗体 (FiGR)

sc-12763
200 µg/ml
RMB2377.00

GR/NR3C1/Glucocorticoid Receptor (FiGR): m-IgGκ BP-HRP 套装

sc-520590
200 µg Ab, 40 µg BP
RMB2662.00

GR/NR3C1/Glucocorticoid Receptor (FiGR): m-IgG2b BP-HRP 套装

sc-548840
200 µg Ab; 10 µg BP
RMB2662.00

GR/NR3C1/Glucocorticoid Receptor 抗体 (FiGR) X

sc-12763 X
200 µg/0.1 ml
RMB2377.00

GR/NR3C1/Glucocorticoid Receptor 抗体 (FiGR) AC

sc-12763 AC
500 µg/ml, 25% agarose
RMB3129.00

GR/NR3C1/Glucocorticoid Receptor 抗体 (FiGR) HRP

sc-12763 HRP
200 µg/ml
RMB2377.00

GR/NR3C1/Glucocorticoid Receptor 抗体 (FiGR) FITC

sc-12763 FITC
200 µg/ml
RMB2482.00

GR/NR3C1/Glucocorticoid Receptor 抗体 (FiGR) PE

sc-12763 PE
200 µg/ml
RMB2580.00

GR/NR3C1/Glucocorticoid Receptor 抗体 (FiGR) Alexa Fluor® 488

sc-12763 AF488
200 µg/ml
RMB2685.00

GR/NR3C1/Glucocorticoid Receptor 抗体 (FiGR) Alexa Fluor® 546

sc-12763 AF546
200 µg/ml
RMB2685.00

GR/NR3C1/Glucocorticoid Receptor 抗体 (FiGR) Alexa Fluor® 594

sc-12763 AF594
200 µg/ml
RMB2685.00

GR/NR3C1/Glucocorticoid Receptor 抗体 (FiGR) Alexa Fluor® 647

sc-12763 AF647
200 µg/ml
RMB2685.00

GR/NR3C1/Glucocorticoid Receptor 抗体 (FiGR) Alexa Fluor® 680

sc-12763 AF680
200 µg/ml
RMB2685.00

GR/NR3C1/Glucocorticoid Receptor 抗体 (FiGR) Alexa Fluor® 790

sc-12763 AF790
200 µg/ml
RMB2685.00

Hola, pertenezco al IDICER-CONICET Argentina, quisiera saber cuáles son las condiciones para solicitar una muestra de 10mg de anticuerpo, por ejemplo de GR/NR3C1/Glucocorticoid Receptor Anticuerpo (FiGR): sc-12763. Gracias

Asked by: Evangelina
Gracias por tu pregunta. Para obtener información sobre cómo recibir una muestra de 10 µg, comuníquese con nuestro Departamento de Servicio Técnico (o con su Distribuidor local).
Answered by: Tech Support Europe
Date published: 2021-12-01

When should the TransCruz reagent sc-12763 X be used instead of the standard form sc-12763?

Asked by: Trav11
Thank you for your question. We recommend using the TransCruz reagent form when performing ChIP or GelShift assays. This form can also be used in other applications such as Western Blot or IHC, but the dilution should be adjusted by a factor of 10 to account for the higher original concentration.
Answered by: Technical Support
Date published: 2017-02-24
  • y_2025, m_9, d_7, h_4CST
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Rated 5 out of 5 by from Western blotThis antibody work well in western blot (goat liver:dilute1:200)
Date published: 2018-03-11
Rated 5 out of 5 by from GR FiGRExcelent antibody for western blot. Detected GR at expected size in 15 ug total proteine lysate, wet transfer one hour at 450 mAmps on PVDF membrane, overnight blocking with 5% nonfat dry milk in PBS, one hour incubation at RT with 1:500 anti GR in 5% PBS with 0,2%Tween followed by one hour incubation with 1:10.000 anti mouse (sc-358919) HRP conjugated antibody and detection with ECL prime substrate followed by short film exposure (under 1 minute) and automatic processing.
Date published: 2017-09-25
Rated 4 out of 5 by from Worked well for Western with Jurkat samplesWorked well for Western with Jurkat samples. -SCBT Publication Review
Date published: 2015-04-22
Rated 4 out of 5 by from Western blot positive with transfected HeLaWestern blot positive with transfected HeLa and mouse embryonic fibroblasts. -SCBT QC
Date published: 2015-01-31
Rated 4 out of 5 by from Single strong band observed in KNRK nuclearSingle strong band observed in KNRK nuclear extract. -SCBT QC
Date published: 2013-08-29
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GR/NR3C1/Glucocorticoid Receptor 抗体 (FiGR) is rated 4.4 out of 5 by 5.
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